AST Cancer Research Results

AST, Aspartate Aminotransferase: Click to Expand ⟱
Source:
Type:
AST (Aspartate Aminotransferase) is an enzyme found in various tissues throughout the body, including the liver, heart, muscles, kidneys, and brain. Elevated levels of AST in the blood can be an indicator of tissue damage or disease.
AST levels can be elevated in certain types of cancer.
Used as a clinical biomarker for Liver function


Scientific Papers found: Click to Expand⟱
6781- EGCG,    Scientific opinion on the safety of green tea catechins
- Review, Nor, NA
*hepatoP↓, *Dose↝, *ALAT↑, *AST↑,
7803- IBC,    Isobavachalcone induces hepatotoxicity in zebrafish embryos and HepG2 cells via the System Xc--GSH-GPX4 signaling pathway in ferroptosis response
- in-vivo, Nor, NA - in-vitro, NA, HepG2
*hepatoP↓, *ALAT↑, *AST↑, *ROS↑, *MDA↑, *Catalase↓, *GSH↓, *GPx↓, *i-Iron↑,
8548- Matr,    The DHCR7 is the key target of lipotoxic liver injury caused by matrine through abnormal activation of the cholesterol synthesis pathway
- in-vitro, LiverDam, NA
*insect↑, *hepatoP↓, *ALAT↑, *AST↑, *CYP51/14LDM↑, *DHCR7↑, *toxicity↝,
8802- MT/VAE,    Pharmakokinetics of Mistletoe Lectins after Intravenous Application of a Mistletoe Product in Healthy Subjects
- Trial, Nor, NA
*Dose↝, *hepatoP↑, *Half-Life↝, *ALAT↑, *AST↑, toxicity↝, Dose↝,

Showing Research Papers: 1 to 4 of 4

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4

Pathway results for Effect on Cancer / Diseased Cells:


Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 1,  

Functional Outcomes(tgid=23) ⓘ

toxicity↝, 1,  
Total Targets: 2

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

Catalase↓, 1,   GPx↓, 1,   GSH↓, 1,   i-Iron↑, 1,   MDA↑, 1,   ROS↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↑, 4,   CYP51/14LDM↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

DHCR7↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 2,   Half-Life↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↑, 4,   AST↑, 4,  

Functional Outcomes(tgid=23) ⓘ

hepatoP↓, 3,   hepatoP↑, 1,   toxicity↝, 1,  

Infection & Microbiome(tgid=24) ⓘ

insect↑, 1,  
Total Targets: 17

Scientific Paper Hit Count for: AST, Aspartate Aminotransferase
1 EGCG (Epigallocatechin Gallate)
1 Isobavachalcone
1 Matrine
1 Mistletoe/Viscum album Extracts
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:691  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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