DNAdam Cancer Research Results

DNAdam, DNA damage: Click to Expand ⟱
Source: HalifaxProj(prevent)
Type:
DNA damage plays a crucial role in the development of cancer. The integrity of DNA is essential for the proper functioning of cells, and when DNA is damaged, it can lead to mutations that may contribute to cancer progression.


Scientific Papers found: Click to Expand⟱
5236- AgNPs,    Adaptive regulations of Nrf2 alleviates silver nanoparticles-induced oxidative stress-related liver cells injury
- in-vitro, Liver, HepG2 - in-vitro, Nor, L02
tumCV↓, ROS↑, *ROS↑, DNAdam↑, *DNAdam↑, eff↓, selectivity↑,
5144- AgNPs,    Differential effects of silver nanoparticles on DNA damage and DNA repair gene expression in Ogg1-deficient and wild type mice
- in-vivo, Nor, NA
*DNAdam↑, *toxicity↝, eff↝,
1764- PG,  Cu,    DNA strand break induction and enhanced cytotoxicity of propyl gallate in the presence of copper(II)
- in-vitro, Nor, GM05757
*DNAdam↑, *ROS↑, *Dose∅, *DNAdam∅,

Showing Research Papers: 1 to 3 of 3

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

ROS↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

tumCV↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

eff↓, 1,   eff↝, 1,   selectivity↑, 1,  
Total Targets: 6

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

ROS↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 3,   DNAdam∅, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose∅, 1,  

Functional Outcomes(tgid=23) ⓘ

toxicity↝, 1,  
Total Targets: 5

Scientific Paper Hit Count for: DNAdam, DNA damage
2 Silver-NanoParticles
1 Propyl gallate
1 Copper and Cu NanoParticles
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:82  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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