eff Cancer Research Results

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Power to enhance an anti cancer effect
Scientific Papers found: Click to Expand⟱
9261- Acai, EO,    Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich acai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers
- Study, Nor, NA
*Dose?, *BioAv↝, *eff↑,
3968- ACNs,    Enhanced Neuronal Activation with Blueberry Supplementation in Mild Cognitive Impairment
- Human, AD, NA
*BOLD↑, *cognitive?, *eff↑,
4549- AgNPs,    Silver nanoparticles: Synthesis, medical applications and biosafety
- Review, Var, NA - Review, Diabetic, NA
ROS↑, eff↑, other↝, DNAdam↑, EPR↑, eff↑, eff↑, TumMeta↓, angioG↓, *Bacteria↓, *eff↑, *AntiViral↑, *AntiFungal↑, eff↑, eff↑, TumCP↓, tumCV↓, P53↝, HIF-1↓, TumCCA↑, lipid-P↑, ATP↓, Cyt‑c↑, MMPs↓, PI3K↓, Akt↓, *Wound Healing↑, *Inflam↓, *Bone Healing↑, *glucose↓, *AntiDiabetic↑, *BBB↑,
4547- AgNPs,  GoldNP,  VitC,    Exploration of Biocompatible Ascorbic Acid Reduced and Stabilized Gold Nanoparticles, as Sensitive and Selective Detection Nanoplatform for Silver Ion in Solution
- Study, Var, NA
*eff↑,
4545- AgNPs,  VitC,  Citrate,    Ascorbic Acid-assisted Green Synthesis of Silver Nanoparticles: pH and Stability Study
- Study, Var, NA
*other↝, *other↝, *eff↑, *eff↑,
4544- AgNPs,  VitC,    Current Research on Silver Nanoparticles: Synthesis, Characterization, and Applications
- Review, Nor, NA
*Bacteria↓, *eff↑,
4423- AgNPs,    Pongamia pinnata seed extract-mediated green synthesis of silver nanoparticle loaded nanogel for estimation of their antipsoriatic properties
- in-vivo, PSA, NA
*eff↑, *other↑,
4360- AgNPs,    Silver Nanoparticles as Real Topical Bullets for Wound Healing
- Study, Nor, NA
*other↝, *toxicity↓, *eff↑, *eff↑, *Inflam↓, *IL6↓, *TGF-β↑, *MMP9↓, *eff↑,
4359- AgNPs,    Antimicrobial Silver Nanoparticles for Wound Healing Application: Progress and Future Trends
- Review, Wounds, NA
*Bacteria↓, *eff↑, *other↝, *toxicity↓,
4424- AgNPs,    Understanding the prospective of nano-formulations towards the treatment of psoriasis
- in-vivo, PSA, NA
*eff↑,
4447- AgNPs,    Anti-inflammatory action of silver nanoparticles in vivo: systematic review and meta-analysis
- Review, Nor, NA
*Inflam↓, *COX2/PTGS2↓, *ROS↓, *Dose↝, *eff↑, *toxicity↓, *IL4↑, *IL5↑, *IL10↑, *IL1↓, *IL6↓, *TNF-α↓, *NF-kB↓, *MDA↓, *GSH↑,
4365- AgNPs,    Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview
- Review, Var, NA
ROS↑, *toxicity↓, *Bacteria↓, *Inf↓, *Diff↑, *eff↑, RadioS↑, selectivity↑,
2286- AgNPs,    Short-term changes in intracellular ROS localisation after the silver nanoparticles exposure depending on particle size
- in-vitro, Nor, 3T3
*eff↑, *mt-ROS↑, *eff↑,
2207- AgNPs,  TQ,    Protective effects of Nigella sativa L. seeds aqueous extract-based silver nanoparticles on sepsis-induced damages in rats
- in-vivo, Nor, NA
*eff↑, *RenoP↑, *hepatoP↑, *MDA↓, *SOD↑, *GSH↑, *TNF-α↓, *IL1β↓,
2205- AgNPs,    Potential protective efficacy of biogenic silver nanoparticles synthesised from earthworm extract in a septic mice model
- in-vivo, Nor, NA
*Dose↝, *eff↑, *RenoP↑, *antiOx↑, *MDA↓, *NO↓, *hepatoP↑, *toxicity↝, *GSH↑, *SOD↑, *GSTs↑, *Catalase↑,
1916- AL,    Allicin Bioavailability and Bioequivalence from Garlic Supplements and Garlic Foods
- Review, Nor, NA
*BioAv↝, *eff↓, *BioAv↝, *BioAv↝, *eff↑, *Half-Life∅, *eff↑, *eff↑, *Dose∅, *eff↑,
3439- ALA,    The effect of alpha lipoic acid on the developmental competence of mouse isolated preantral follicles
- in-vitro, Nor, NA
*ROS↓, *TAC↑, *eff↑, *SOD↑, *GPx↑, *Catalase↑, *GlucoseCon↑, *antiOx↑,
3456- ALA,    Renal-Protective Roles of Lipoic Acid in Kidney Disease
- Review, Nor, NA
*RenoP↑, *ROS↓, *antiOx↑, *Inflam↓, *Sepsis↓, *IronCh↑, *BUN↓, *creat↓, *TNF-α↓, *IL6↓, *IL1β↓, *MDA↓, *NRF2↑, *HO-1↑, *NQO1↑, *chemoP↑, *eff↑, *NF-kB↓,
3550- ALA,    Mitochondrial Dysfunction and Alpha-Lipoic Acid: Beneficial or Harmful in Alzheimer's Disease?
- Review, AD, NA
*antiOx↑, *Inflam↓, *PGE2↓, *COX2/PTGS2↓, *iNOS↓, *TNF-α↓, *IL1β↓, *IL6↓, *BioAv↓, *Ach↑, *ROS↓, *cognitive↑, *neuroP↑, *BBB↑, *Half-Life↓, *BioAv↑, *Casp3↓, *Casp9↓, *ChAT↑, *cognitive↑, *eff↑, *cAMP↑, *IL2↓, *INF-γ↓, *TNF-α↓, *SIRT1↑, *SOD↑, *GPx↑, *MDA↓, *NRF2↑,
1554- Api,    A Review on Flavonoid Apigenin: Dietary Intake, ADME, Antimicrobial Effects, and Interactions with Human Gut Microbiota
- Review, Nor, NA
*BioAv↑, *BioAv↑, *BioAv↑, *BioAv↓, *eff↑,
3817- Aroma,    Therapeutic potential of aromatic plant extracts in Alzheimer's disease: Comprehensive review of their underlying mechanisms
- Review, AD, NA
*BChE↓, *AChE↓, *other↓, *other?, *Ach?, *eff↑, *antiOx↑, *ROS↓, *cognitive↑, *Mood↑, *Sleep↑,
2461- ASA,    Aspirin and platelets: the antiplatelet action of aspirin and its role in thrombosis treatment and prophylaxis
- Review, Nor, NA
*AntiAg↑, *COX1↓, *eff↑,
5420- ASTX,    A New Tailored Nanodroplet Carrier of Astaxanthin Can Improve Its Pharmacokinetic Profile and Antioxidant and Anti-Inflammatory Efficacies
- in-vivo, Nor, NA
*eff↑, *SOD↑, *BioAv↑,
5371- AV,    effect_of_Aloe_vera_polysaccharides_extracts_on_macrophages_functions">Assessment of the immunomodulatory effect of Aloe vera polysaccharides extracts on macrophages functions
- Study, Nor, NA
*eff↑, *IL6↑, *toxicity↓, *Imm↑,
5574- B-Gluc,    Beta Glucan: Health Benefits in Obesity and Metabolic Syndrome
- Review, Obesity, NA
*BioAv↑, *toxicity↓, *Imm↑, *eff↑, *Risk↓, *Weight↓, *eff↝, *BP↓, *GutMicro↑, *eff↓,
1530- Ba,    Baicalein Decreases Hydrogen Peroxide‐Induced Damage to NG108‐15 Cells via Upregulation of Nrf2
- in-vitro, Nor, NG108-15
*12LOX↓, *ROS↓, *NRF2↑, *eff↑,
2482- Ba,    Modulation of Neuroinflammation in Poststroke Rehabilitation: The Role of 12/15-Lipoxygenase Inhibition and Baicalein
- Review, Stroke, NA
*12LOX↓, *neuroP↑, *eff↑,
2605- Ba,  BA,    Potential therapeutic effects of baicalin and baicalein
- Review, Var, NA - Review, Stroke, NA - Review, IBD, NA - Review, Arthritis, NA - Review, AD, NA - Review, Park, NA
cardioP↑, Inflam↓, cognitive↑, *hepatoP↑, *ROS?, *SOD↑, *GSH↑, *MMP↑, *GutMicro↑, ChemoSen↑, *TNF-α↓, *IL10↑, *IL6↓, *eff↑, *ROS↓, *COX2/PTGS2↓, *NF-kB↓, *STAT3↓, *PGE2↓, *MPO↓, *IL1β↓, *MMP2↓, *MMP9↓, *β-Amyloid↓, *neuroP↑, *Dose↝, *BioAv↝, *BioAv↝, *BBB↑, *BDNF↑,
2625- Ba,  LT,    Baicalein and luteolin inhibit ischemia/reperfusion-induced ferroptosis in rat cardiomyocyte
- in-vivo, Stroke, NA
*lipid-P↓, *ACSL4∅, *NRF2∅, *GPx4∅, *Ferroptosis↓, *ROS↓, *MDA↓, *eff↑, *HO-1∅,
2624- Ba,    Baicalein inhibition of hydrogen peroxide-induced apoptosis via ROS-dependent heme oxygenase 1 gene expression
- in-vitro, Nor, RAW264.7
*HO-1↑, *ERK↑, *ROS↓, *eff↑, *MMP↑, *Cyt‑c∅,
5552- BBM,    Effects of berbamine against myocardial ischemia/reperfusion injury: Activation of the 5' adenosine monophosphate‐activated protein kinase/nuclear factor erythroid 2‐related factor pathway and changes in the mitochondrial state
- in-vivo, Stroke, NA
*eff↑, *ROS↓, *mtDam↓, *AMPK↑, *NRF2↑, *NADPH↑, *HO-1↑, *cardioP↑,
2689- BBR,    Berberine protects against glutamate-induced oxidative stress and apoptosis in PC12 and N2a cells
- in-vitro, Nor, PC12 - in-vitro, AD, NA - in-vitro, Stroke, NA
*ROS↓, *lipid-P↓, *DNAdam↓, *GSH↑, *SOD↑, *eff↑, *cl‑Casp3↓, *BAX↓, *neuroP↑, *Dose↝, *Ca+2↓,
3754- BBR,  CUR,  EGCG,  Hup,    Traditional Chinese medicinal herbs as potential AChE inhibitors for anti-Alzheimer’s disease: A review
- Review, AD, NA
*AChE↓, *Aβ↓, *LDL↓, *RenoP↑, *BChE↓, *eff↑, *BACE/β-secretase↓, *AChE↓, *Synergy↑,
4275- BBR,    Pharmacological effects of berberine on mood disorders
- Review, AD, NA
*antiOx↑, *Inflam↓, *hepatoP↑, *eff↑, *5HT↑, *Mood↑, *BDNF↑,
6502- BCP,    Enhanced Oral Bioavailability of β-Caryophyllene in Healthy Subjects Using the VESIsorb® Formulation Technology, a Novel Self-Emulsifying Drug Delivery System (SEDDS)
- Study, Nor, NA
*BioAv↑, *BioAv↓, *BioAv↓, *eff↑,
5561- betaCar,    Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer’s Disease
- Review, AD, NA
*ROS↓, *cognitive↑, *BBB↑, *lipid-P↓, *eff↑,
5563- betaCar,    Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer's Disease
- Review, AD, NA
*BBB↑, *lipid-P↓, *eff↑, *cognitive↑,
3988- betaCar,  Lut,  Zeax,    Effects of egg consumption on carotenoid absorption from co-consumed, raw vegetables
- Trial, AD, NA
*eff↑, *Synergy↑, *Synergy↑,
9176- BITC,  Nast,    A 14-Day Double-Blind, Randomized, Controlled Crossover Intervention Study with Anti-Bacterial Benzyl Isothiocyanate from Nasturtium (Tropaeolum majus) on Human Gut Microbiome and Host Defense
- Study, UTI, NA
*AntiBio↑, *Dose?, *DEFB1↑, *GutMicro∅, *eff↑,
9174- BITC,    Benzyl isothiocyanate as an alternative to antibiotics? a comparative in vivo study using Pseudomonas aeruginosa
- in-vivo, Nor, NA
*AntiBio↑, *eff↑, *toxicity↝,
9175- BITC,  PEITC,  AITC,    Isothiocyanates in medicine: A comprehensive review on phenylethyl-, allyl-, and benzyl-isothiocyanates
- Review, Nor, NA
*Inflam↓, *antiOx↑, *AntiBio↑, *BioAv↝, *BioAv↑, *TNF-α↓, *IL10↓, *antiAll↑, *NRF2↑, *SOD↑, *GPx↑, *HO-1↑, *NQO1↑, *GSH↑, *GSTs↑, *hepatoP↑, *MDA↓, *Catalase↑, *ROS↓, *ROS⇅, *ROS↑, *IP-10/CXCL-10↓, *CD40↓, STAT1↓, iNOS↓, STAT3↓, IL6↓, *MPO↓, Casp3↑, Casp8↑, Casp9↑, mtDam↑, compIV↓, Cyt‑c↑, SDH↓, AIF↑, p‑Akt↓, PTEN↑, MMP2↓, MMP9↓, TumCCA↑, CDK1↓, CDC25↓, *eff↑, *toxicity↝, *eff↑, *eff↑, EMT↓, *AntiAg↑,
5656- BNL,    Role of borneol as enhancer in drug formulation: A review
- Review, Nor, NA - Review, Stroke, NA - Review, AD, NA
*eff↑, BBB↑, ChemoSen↑, *Inflam↓, *NO↓, *TNF-α↓, *IL6↓, *Bacteria↓, *Synergy↑, *Aβ↓, *SOD↑, *neuroP↑, *EPR↑, toxicity↓, P-gp/ABCB1↓, Synergy↑, other↝,
5666- BNL,    Exploring the potential to enhance drug distribution in the brain subregion via intranasal delivery of nanoemulsion in combination with borneol as a guider
- in-vivo, AD, NA
*BioAv↑, *eff↑, *Dose↝, *P-gp/ABCB1↓, *BBB↑, *NF-kB↓, *IL1β↓, *MMP9↓,
5667- BNL,    Preparation and evaluation of sustained-release solid dispersions co-loading gastrodin with borneol as an oral brain-targeting enhancer
- in-vivo, Nor, NA
*BioEnh↑, *eff↑, *BBB↑,
5669- BNL,    Comparison of pharmacological activity and safety of different stereochemical configurations of borneol: L-borneol, D-borneol, and synthetic borneol
- Review, Nor, NA - Review, AD, NA - Review, Stroke, NA
*eff↑, *eff↑, *toxicity↝, *Inflam↓, *Bacteria↓, *neuroP↑, *Half-Life↝, *BBB↑, *BioEnh↑, *P-gp/ABCB1↓, *CYP3A4↓, *ROS↓, *neuroP↑,
4625- Bor,    Boron and Inflammation
- Review, Arthritis, NA - Review, ostP, NA
*Risk↓, *eff↑, *SOD↑, *NF-kB↓, *Risk↓, *CRP↓, *TNF-α↓, *Wound Healing↑,
4624- Bor,  VitD3,    Boron as a Medicinal Ingredient in Oral Natural Health Products
- Review, Pca, NA
*Half-Life↝, *eff↑, PSA↓, TumVol↓, IGF-1↓, *memory↓, *motorD↓,
3868- Bos,    Enhanced absorption of boswellic acids by a lecithin delivery form (Phytosome(®)) of Boswellia extract
- in-vivo, Nor, NA
*Inflam↓, *BioAv↓, *BioAv↑, *eff↑,
3867- Bos,    Effect of food intake on the bioavailability of boswellic acids from a herbal preparation in healthy volunteers
- Human, Nor, NA
*eff↑, BioAv↝,
2775- Bos,    The journey of boswellic acids from synthesis to pharmacological activities
- Review, Var, NA - Review, AD, NA - Review, PSA, NA
ROS↑, ER Stress↑, TumCG↓, Apoptosis↑, Inflam↓, ChemoSen↑, Casp↑, ERK↓, cl‑PARP↑, AR↓, cycD1/CCND1↓, VEGFR2/KDR/Flk1↓, CXCR4↓, radioP↑, NF-kB↓, VEGF↓, P21↑, Wnt↓, β-catenin/ZEB1↓, Cyt‑c↑, MMP2↓, MMP1↓, MMP9↓, PI3K↓, MAPK↓, JNK↑, *5LO↓, *NRF2↑, *HO-1↑, *MDA↓, *SOD↑, *hepatoP↑, *ALAT↓, *AST↓, *LDH↑, *CRP↓, *COX2/PTGS2↓, *GSH↑, *ROS↓, *Imm↑, *Dose↝, *eff↑, *neuroP↑, *cognitive↑, *IL6↓, *TNF-α↓, *AntiArt↑, *AntiDiabetic↑, *antiAll↑,

Showing Research Papers: 1 to 50 of 267
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 267

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 4,   Catalase↓, 2,   Fenton↑, 1,   GPx↓, 1,   GPx↑, 1,   GPx4↓, 1,   GSH↓, 4,   GSR↓, 1,   GSTs↓, 1,   GSTs↑, 1,   H2O2↑, 1,   HO-1↓, 1,   HO-1↑, 1,   Iron↑, 1,   Iron↝, 1,   lipid-P↑, 4,   MDA↑, 2,   NQO1↓, 1,   NRF2↓, 1,   NRF2↑, 1,   ROS↓, 3,   ROS↑, 16,   i-ROS↑, 1,   SOD↓, 3,   SOD2↓, 1,   TAC↓, 1,   VitC↓, 1,   VitE↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

CDC25↓, 1,   compIV↓, 1,   mtDam↑, 1,   OXPHOS↓, 1,   PGC-1α↑, 1,   SDH↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ATP↓, 1,   GSK‐3β↑, 1,   SCD1↓, 1,   SIRT1↓, 1,   TCA↝, 1,  

Cell Death(tgid=5) ⓘ

AIF↑, 3,   APAF1↑, 1,   Apoptosis↓, 1,   Apoptosis↑, 12,   ASC↓, 1,   BAD↑, 1,   Bak↓, 1,   Bak↑, 1,   BAX↑, 8,   Bax:Bcl2↑, 2,   Bcl-2↓, 7,   Bcl-xL↓, 2,   BID↑, 2,   Casp↑, 1,   cl‑Casp↑, 1,   Casp1↓, 1,   Casp3↑, 9,   Casp8↑, 5,   Casp9↑, 4,   Cyt‑c↑, 9,   DR5↑, 3,   Fap1↓, 1,   Fas↑, 3,   FasL↑, 1,   Ferroptosis↑, 2,   GranB/GZMB↝, 1,   IAP2/BIRC3↓, 1,   iNOS↓, 2,   p‑MDM2↓, 1,   MOMP↑, 1,   necrosis↑, 1,   p‑p38↑, 1,   Perforin↝, 1,   survivin↓, 1,   XIAP↓, 4,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 9,   p‑Akt↓, 3,   EGFR↑, 2,   ERK↓, 3,   p‑ERK↓, 1,   HER2/EBBR2↓, 1,   HGF/c-Met↓, 1,   IKKα↓, 1,   JAK2↓, 2,   JNK↑, 2,   p‑JNK↑, 1,   MAPK↓, 3,   mTOR↓, 3,   P70S6K↓, 1,   PI3K↓, 7,   p‑PI3K↓, 1,   PKCδ↓, 1,   PTEN↓, 1,   PTEN↑, 2,   p‑Src↓, 1,   STAT3↓, 4,   p‑STAT3↑, 1,   p‑STAT6↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   cMyc↓, 1,   EZH2↓, 1,   FOXO4↑, 1,   H3↓, 1,   H4↓, 1,   HDAC↓, 2,   miR-124-3p↓, 1,   other↝, 2,   tumCV↓, 4,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1,   p‑eIF2α↑, 1,   ER Stress↑, 2,   HSP70/HSPA5↑, 1,   HSP90↓, 1,   HSPs∅, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   LC3II↑, 2,   p62↑, 1,   TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 8,   DNArepair↓, 1,   P53↑, 5,   P53↝, 1,   PARP↑, 2,   cl‑PARP↑, 3,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 2,   CDK4↓, 1,   CDK6↑, 1,   cycA1/CCNA1↓, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 2,   P21↑, 1,   p27/CDKN1B↑, 1,   TumCCA↑, 11,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 1,   CD34↓, 1,   cFos↑, 1,   CSCs↓, 1,   FGF↓, 2,   HH↓, 1,   IGF-1?, 1,   IGF-1↓, 1,   NOTCH1↓, 1,   STAT1↓, 1,   TumCG↓, 4,   TumCP↓, 9,   Wnt↓, 3,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   AXL↓, 1,   Ca+2↑, 4,   i-Ca+2?, 1,   Cdc42↓, 1,   E-cadherin↓, 2,   EMT↓, 3,   FAK↓, 1,   ITGB1↓, 1,   LRP1↓, 1,   MALAT1↓, 1,   MET↓, 1,   p‑MET↓, 1,   MMP1↓, 1,   MMP2↓, 8,   MMP9↓, 7,   MMPs↓, 2,   MTA1↓, 1,   N-cadherin↓, 1,   Rac1↓, 1,   Rho↓, 2,   Snail↓, 1,   TIMP1↑, 1,   TIMP2↓, 1,   TIMP2↑, 2,   TumCI↓, 4,   TumCMig↓, 6,   TumMeta↓, 2,   TumMeta↑, 1,   Tyro3↓, 1,   uPA↓, 1,   Vim↑, 1,   β-catenin/ZEB1↓, 4,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 8,   HIF-1↓, 1,   Hif1a↓, 2,   VEGF↓, 7,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,   CLDN1↓, 1,   EPR↑, 1,   MMP↓, 4,   OATPs↓, 1,   TRPV1↑, 1,   ZO-1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD47↓, 1,   CD8+↑, 2,   COX2/PTGS2↓, 3,   CXCR2↓, 1,   CXCR4↓, 2,   DR4↑, 1,   ICAM-1↓, 2,   IL1β↓, 2,   IL2↑, 1,   IL6↓, 4,   IL8↓, 1,   Imm↑, 2,   Inflam↓, 3,   NF-kB↓, 7,   NF-kB↑, 1,   NK cell↑, 1,   NLRP3↓, 1,   NLRP3↑, 1,   p‑p65↓, 1,   PD-1↓, 1,   PD-L1↓, 3,   PGE2↓, 1,   PSA↓, 2,   TLR4↓, 1,   TNF-α↓, 3,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 2,   ER(estro)↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 2,   BioAv↝, 2,   chemoR↓, 1,   ChemoSen↑, 16,   CYP1A1↓, 1,   DDS↑, 1,   Dose↑, 1,   Dose↝, 3,   eff↓, 4,   eff↑, 19,   eff↝, 3,   Half-Life↝, 1,   MDR1↓, 1,   MRP↓, 1,   P-gp/ABCB1↓, 3,   RadioS↑, 4,   selectivity↑, 10,   Synergy↑, 9,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 2,   CEA↓, 2,   EGFR↑, 2,   EZH2↓, 1,   HER2/EBBR2↓, 1,   IL6↓, 4,   NSE↓, 1,   PD-L1↓, 3,   PSA↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 6,   AntiTum↑, 3,   cachexia↓, 1,   cardioP↑, 2,   chemoP↑, 6,   chemoPv↑, 4,   ChemoSideEff↓, 1,   cognitive↑, 3,   hepatoP↑, 2,   memory↑, 1,   neuroP↑, 2,   NP/CIPN↓, 1,   OS↑, 2,   PFS↑, 1,   QoL↑, 2,   radioP↑, 5,   RenoP↑, 1,   Risk↓, 2,   toxicity↓, 1,   toxicity↝, 1,   TumVol↓, 5,   TumW↓, 2,  
Total Targets: 268

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 2,   antiOx↑, 50,   ARE↑, 1,   Bil↓, 1,   Catalase↑, 21,   DPPH↓, 1,   Fenton↓, 2,   GPx↑, 13,   GPx4↓, 1,   GPx4↑, 1,   GPx4∅, 1,   GSH↑, 31,   GSR↑, 2,   GSTs↑, 7,   H2O2↓, 3,   H2O2↑, 1,   HDL↑, 3,   HDL∅, 1,   HO-1↓, 1,   HO-1↑, 15,   HO-1↝, 1,   HO-1∅, 1,   hyperG↓, 1,   Iron↓, 2,   Iron↑, 1,   Keap1↓, 1,   Keap1↑, 1,   lipid-P↓, 22,   lipid-P↑, 1,   mt-lipid-P↓, 1,   MDA↓, 22,   MPO↓, 7,   NADH↓, 1,   NOX↓, 1,   NOX4↓, 1,   NQO1↑, 6,   NRF2↓, 2,   NRF2↑, 30,   NRF2⇅, 1,   NRF2∅, 1,   RNS↓, 3,   ROS?, 1,   ROS↓, 79,   ROS↑, 4,   ROS⇅, 2,   mt-ROS↑, 1,   selenoP↑, 1,   SOD↑, 39,   TAC↑, 6,   TBARS↓, 4,   Trx↑, 1,   TrxR↑, 1,   uricA↓, 3,   VitE↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   FPN↑, 1,   IronCh↑, 5,   Mets↝, 1,   NCOA4↝, 1,   selm↑, 1,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↓, 1,   compII↑, 1,   compIII↓, 1,   compIII↑, 1,   DRP1/DNM1L↑, 1,   ETC↓, 1,   FIS1↓, 1,   FIS1↑, 1,   Insulin↓, 1,   mitResp↑, 1,   mtDam↓, 4,   PGC-1α↑, 3,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 3,   5LO↓, 3,   ACSL4∅, 1,   adiP↑, 1,   ALAT↓, 8,   ALAT∅, 1,   AMPK↑, 5,   ATP↓, 1,   ATP↑, 5,   cAMP↑, 2,   glucose↓, 2,   GlucoseCon↑, 2,   GSK‐3β↓, 2,   GSK‐3β↑, 1,   GSK‐3β↝, 1,   KeyT↑, 3,   lactateProd↓, 1,   LDL↓, 9,   NAD↑, 1,   NADH:NAD↑, 1,   NADPH↓, 1,   NADPH↑, 2,   PKM2↓, 1,   SIRT1↑, 6,   SIRT2↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 12,   Apoptosis↑, 1,   BAX↓, 4,   Bax:Bcl2↓, 1,   Bcl-2↓, 1,   Bcl-2↑, 3,   Bcl-xL↑, 1,   Casp12↓, 1,   Casp3↓, 12,   Casp3∅, 1,   cl‑Casp3↓, 1,   Casp8↓, 1,   Casp9↓, 3,   Cyt‑c↓, 4,   Cyt‑c↑, 1,   Cyt‑c∅, 3,   Ferroptosis↓, 3,   GranB/GZMB↓, 1,   HEY1↑, 1,   iNOS↓, 9,   p38↓, 1,   p38↑, 1,   p‑p38↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   Akt↑, 5,   AKT1↓, 1,   CREB↑, 1,   ERK↓, 1,   ERK↑, 3,   JAK2↑, 1,   JNK↓, 3,   p‑JNK↓, 1,   MAPK↓, 4,   MAPK↑, 4,   mTOR↓, 4,   mTOR↑, 1,   mTOR↝, 1,   PI3K↓, 1,   PI3K↑, 3,   PKA↑, 2,   PKCδ↓, 1,   PP2A↑, 1,   PTEN↓, 1,   STAT↓, 1,   STAT3↓, 2,   STAT3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   ATF4↓, 1,   FOXO↑, 1,   HDAC?, 1,   HDAC↓, 1,   other?, 3,   other↓, 7,   other↑, 19,   other↝, 29,   SOX9↑, 1,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   p‑eIF2α↓, 1,   ER Stress↓, 3,   ER Stress↑, 1,   GRP78/BiP↓, 3,   HSF1↑, 2,   HSP70/HSPA5↑, 2,   HSP70/HSPA5↝, 1,   HSPs↑, 2,   IRE1↓, 2,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

LC3‑Ⅱ/LC3‑Ⅰ↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

8-oxo-dG↓, 1,   DNAdam↓, 7,   P53↑, 1,   PARP↓, 1,   γH2AX↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,   P21↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP2↑, 1,   CHIP↑, 1,   Choline↑, 1,   Diff↑, 3,   Diff↝, 1,   neuroG↑, 1,   NOTCH↑, 1,   TumCP↓, 1,   tyrosinase↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↓, 1,   AntiAg↑, 9,   Ca+2↓, 2,   Ca+2↑, 2,   Ca+2↝, 1,   Cartilage↑, 1,   COL2A1↑, 1,   EMT↓, 1,   F-actin↑, 1,   FAK↑, 1,   MMP13↓, 1,   MMP2↓, 1,   MMP9↓, 6,   MMP9↑, 1,   MMPs↑, 1,   PAI-1/SERPINE1↓, 1,   SMAD3↓, 1,   Snail↑, 1,   TGF-β↑, 2,   TGF-β1↓, 1,   TIMP1↓, 1,   TumCI↓, 1,   TumCMig↓, 1,   Twist↑, 1,   Vim↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   Hif1a∅, 1,   NO↓, 10,   NO↑, 2,   TXA2↓, 1,   VEGF↑, 3,  

Barriers & Transport(tgid=15) ⓘ

AQPs↓, 1,   BBB↓, 1,   BBB↑, 27,   BBB↝, 1,   BBB∅, 2,   CLDN1↓, 1,   CLDN1↑, 1,   EPR↑, 1,   GastroP↑, 3,   IBI↑, 2,   MMP↓, 1,   MMP↑, 8,   MMP↝, 1,   MMP∅, 1,   OCLN↑, 1,   TJ↓, 1,   TJ↑, 1,   TRPV3↑, 1,   VGSC↓, 1,   ZO-1↓, 1,   ZO-1↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD25+↑, 1,   CD4+↑, 3,   CD40↓, 1,   CD8+↑, 1,   COX1↓, 3,   COX2/PTGS2↓, 16,   DEFB1↑, 1,   Eos↓, 1,   FOXP3↑, 1,   HMGB1↓, 1,   IFN-γ↓, 2,   IFN-γ↑, 2,   IgE↓, 1,   IL1↓, 3,   IL10↓, 1,   IL10↑, 6,   IL10∅, 1,   IL13↑, 1,   IL17↓, 3,   IL17∅, 1,   IL1β↓, 19,   IL2↓, 1,   IL22↓, 1,   IL4↓, 1,   IL4↑, 2,   IL4∅, 1,   IL5↑, 1,   IL6?, 1,   IL6↓, 23,   IL6↑, 3,   IL8?, 1,   IL8↓, 2,   Imm↑, 12,   INF-γ↓, 1,   Inflam↓, 73,   Inflam↑, 1,   IP-10/CXCL-10↓, 1,   IRF3↓, 1,   LPS↓, 1,   M2 MC↑, 1,   MCP1/CCL2↓, 1,   MyD88↓, 2,   NeuroI↓, 2,   NF-kB↓, 21,   NF-kB↑, 2,   NLRP3↓, 5,   NLRP3↑, 1,   p65↓, 1,   PAF↓, 1,   PGE2↓, 6,   PSA↓, 1,   TLR1↓, 1,   TLR2↓, 2,   TLR4↓, 2,   TNF-α↓, 34,   TNF-α↑, 1,   Treg lymp↝, 1,  

Cellular Microenvironment(tgid=17) ⓘ

Temp↝, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5-AR↓, 1,   5HT↑, 2,   Ach?, 1,   Ach↑, 5,   AChE↓, 21,   AChE∅, 1,   ADAM10↑, 1,   BChE↓, 9,   BDNF↑, 14,   BrainVol↑, 1,   ChAT↑, 1,   GABA↑, 2,   MAOA↓, 1,   NMDAR↑, 1,   PSD95↑, 1,   SNAP25↑, 1,   TrkB↑, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 1,   APP↓, 4,   Aβ↓, 25,   Aβ42↓, 1,   BACE/β-secretase↓, 9,   IDE↑, 1,   tau↓, 3,   p‑tau↓, 7,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 1,   GPER↑, 1,   PPARα↑, 1,   PPARγ↓, 1,   PPARγ↑, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 14,   BioAv↑, 44,   BioAv⇅, 1,   BioAv↝, 18,   BioEnh↑, 3,   ChemoSen↑, 1,   CompStab↓, 1,   CompStab↑, 4,   CompStab↝, 2,   CYP3A4↓, 1,   DDS↑, 1,   Dose?, 6,   Dose↓, 7,   Dose↑, 4,   Dose↝, 80,   Dose∅, 1,   eff?, 1,   eff↓, 5,   eff↑, 299,   eff↝, 8,   GSTA1↑, 1,   GSTP1/GSTπ↑, 1,   Half-Life↓, 2,   Half-Life↑, 3,   Half-Life↝, 10,   Half-Life∅, 1,   P-gp/ABCB1↓, 2,   P450↓, 1,   Synergy↑, 12,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 8,   ALAT∅, 1,   ALP↓, 2,   anemia↓, 1,   AR↓, 1,   AST↓, 8,   AST∅, 1,   BG↓, 2,   Bil↓, 1,   BloodF↑, 3,   BMD↑, 3,   BP↓, 10,   BUN↓, 2,   colonLen↑, 1,   creat↓, 4,   CRP↓, 4,   Ferritin↓, 1,   FEV1↑, 2,   HemoG↑, 1,   IL6?, 1,   IL6↓, 23,   IL6↑, 3,   KeyT↑, 3,   LDH↓, 1,   LDH↑, 1,   NOS2↓, 2,   PEF↑, 1,   PSA↓, 1,   PV↓, 1,   RBC↑, 1,   SpO2↑, 1,   TC↓, 1,   TG/TAG↓, 1,   TMAO↑, 3,   TMAO⇅, 1,   UFR↑, 1,   UR↓, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   antiAll↑, 11,   AntiArt↑, 2,   AntiCan↑, 5,   antiD↓, 1,   AntiDiabetic↑, 8,   antiPs↑, 1,   AntiTum↑, 1,   ANXi↓, 1,   BOLD↑, 1,   Bone Healing↑, 1,   cardioP↑, 21,   CardioT↓, 2,   chemoP↑, 3,   chemoPv↑, 4,   cognitive?, 1,   cognitive↓, 3,   cognitive↑, 59,   hepatoP↓, 1,   hepatoP↑, 17,   Learn↑, 1,   memory↓, 2,   memory↑, 30,   memory∅, 1,   Mood?, 1,   Mood↑, 4,   motorD↓, 1,   motorD↑, 12,   MusCon↓, 1,   neuroP?, 1,   neuroP↑, 47,   Obesity↓, 5,   OS↓, 1,   OS↑, 5,   Pain↓, 8,   PDE4↓, 1,   QoL↑, 1,   radioP↑, 2,   RenoP↑, 10,   Risk↓, 4,   Risk↑, 1,   Sleep↑, 4,   Strength↑, 1,   Stress↓, 3,   Stroke↓, 8,   toxicity↓, 28,   toxicity↑, 1,   toxicity↝, 6,   toxicity∅, 1,   Weight↓, 2,   Weight↑, 1,   Wound Healing↑, 4,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 10,   AntiFungal↑, 3,   AntiViral↑, 4,   Bacteria↓, 16,   Dysb↓, 1,   GutMicro↑, 10,   GutMicro∅, 1,   Inf↓, 2,   Sepsis↓, 6,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr?, 1,   Ingr↑, 5,   Ingr↝, 10,   Phen?, 1,   Phen↑, 1,   Poly↑, 2,  
Total Targets: 460

Scientific Paper Hit Count for: eff, efficacy
16 Magnetic Fields
14 Silver-NanoParticles
13 Selenium NanoParticles
10 Chlorogenic acid
8 Choline
7 Thymoquinone
7 Exercise
7 Mung Bean Sprouts
6 buckwheat sprouts
5 Vitamin C (Ascorbic Acid)
5 Baicalein
4 Luteolin
4 Lutein
4 borneol
4 Caffeic acid
4 Ginkgo biloba-EGb 761
4 Hydrogen Gas
4 Moringa oleifera
4 Resveratrol
3 Alpha-Lipoic-Acid
3 Berberine
3 Curcumin
3 beta-carotene(VitA)
3 Zeaxanthin
3 Benzyl isothiocyanate
3 Vitamin D3
3 Boswellia (frankincense)
3 Centella asiatica / Gotu kola → asiaticoside
3 Eugenol
3 Gamma-aminobutyric acid
3 Ginseng
3 Lycopene
3 MCT oil
3 Moringin
3 nicotinamide adenine dinucleotide
3 Selenite (Sodium)
2 Gold NanoParticles
2 EGCG (Epigallocatechin Gallate)
2 Nasturtium, Indian Cress
2 Boron
2 Chlorophyllin
2 Citicoline, CDP-Choline
2 Calorie Restriction Mimetics
2 diet Methionine-Restricted Diet
2 diet Short Term Fasting
2 Fisetin
2 Flaxseed/Linseed
2 SDG/lignans
2 phytic acid, Inositol hexakisphosphate
2 Ginkgo biloba
2 Grapeseed extract
2 HydroxyCitric Acid
2 Hyperoside
2 isoquercitrin
2 Isothiocyanates
2 Sulforaphane (mainly Broccoli)
2 Potassium
2 L-Theanine
2 Melatonin
2 Mushroom Lion’s Mane, Hericium erinaceus
2 Radio Frequency
2 Rosmarinic acid
2 Shikonin
2 Spirulina(Arthrospira/Limnospira)
2 Vitamin B1/Thiamine
1 Açaí, Euterpe oleracea
1 Anthocyanins
1 Citric Acid
1 Allicin (mainly Garlic)
1 Apigenin (mainly Parsley)
1 Aromatherapy
1 Aspirin
1 Astaxanthin
1 Aloe anthraquinones
1 beta-glucans
1 Baicalin
1 Berbamine
1 Huperzine A/Huperzia serrata
1 Beta-Caryophyllene
1 Phenethyl isothiocyanate
1 Allyl isothiocyanate
1 Black Rice, Oryza sativa
1 brusatol
1 Bruteridin(bergamot juice)
1 α-Bisabolol / Chamomile oil
1 Black turtle bean
1 Rutin
1 Capsaicin
1 Carvacrol
1 Camu camu
1 Chocolate
1 Chrysin
1 Cichoric acid / Chicoric acid
1 Carvone
1 Cysteamine
1 Diclofenac
1 Docosahexaenoic Acid
1 Dihydrocaffeic Acid
1 2-DeoxyGlucose
1 Dandelion Root
1 Radiotherapy/Radiation
1 Echinacea
1 Protocatechuic acid
1 Electrical Pulses
1 Folic Acid, Vit B9
1 Flickering Light Stimulation
1 Formononetin
1 Crocetin
1 Salvia officinalis
1 Lemon Balm/Melissa officinalis
1 Ginkgolide B
1 Ginger/6-Shogaol/Gingerol
1 Orlistat
1 Honokiol
1 High-Ozonide Oil
1 isoflavones
1 doxorubicin
1 Lactoferrin/Talactoferrin
1 Magnolol
1 Isovitexin
1 Vitexin
1 Hyperthermia
1 Magnetic Field Rotating
1 Magnesium
1 Morin
1 Mucuna pruriens/Velvet Bean
1 Methylsulfonylmethane
1 Mushroom Maitake
1 Naringin
1 Nimbolide
1 No Product/Mechanism Only
1 Peppermint
1 Patchouli Oil (Pogostemon cablin)
1 Purple Corn / Purple Maize
1 Phycocyanin
1 Piperine
1 Piperlongumine
1 Phosphatidylserine
1 Parthenolide
1 Pterostilbene
1 α-Santalol/Sandalwood oil
1 Metformin
1 Taurine
1 Thymol-Thymus vulgaris
1 Ursolic acid
1 Marjoram (Origanum majorana)
1 Vitamin B3,Niacin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:961  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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