Dose Cancer Research Results

Dose, Dosage: Click to Expand ⟱
Source:
Type:
Drug dosage vs efficacy, and actual dosage number of research papers.
Scientific Papers found: Click to Expand⟱
5943- Cela,    Celastrol: A Spectrum of Treatment Opportunities in Chronic Diseases
- Review, Arthritis, NA - Review, IBD, NA - Review, AD, NA - Review, Park, NA
*other↝, *other↝, *CRP↓, *eff↝, *other↑, *CXCR4↓, *IL1β↓, *IL6↓, *IL17↓, *IL18↓, *TNF-α↓, *MMP9↓, *PGE2↓, *COX1↓, *COX2/PTGS2↓, *PI3K↓, *Akt↓, *other↑, TumCCA↑, Apoptosis↑, ROS↑, JNK↑, TumAuto↑, Hif1a↓, BNIP3↝, HSP90↓, Fas↑, FasL↑, ETC↓, VEGF↓, angioG↓, RadioS↑, *neuroP↑, *HSP70/HSPA5↑, *ROS↓, *MMP↑, *Cyt‑c↓, *Casp3↓, *Casp9↓, *MAPK↓, *Dose⇅, *HSPs↑, BioAv↓, Dose↝,
2079- HNK,    Honokiol Microemulsion Causes Stage-Dependent Toxicity Via Dual Roles in Oxidation-Reduction and Apoptosis through FoxO Signaling Pathway
- in-vitro, Nor, PC12
*toxicity↝, *ROS↓, *ROS↑, *Dose⇅, *BioAv↑, *BioAv↓, *ROS⇅, *SOD↓, *toxicity↑,
4441- SeNPs,    The Role of Selenium Nanoparticles in the Treatment of Liver Pathologies of Various Natures
- Review, Nor, NA
*ROS↓, *hepatoP↑, *selenoP↑, *ALAT↓, *AST↓, *GSH↑, *GPx↑, *TNF-α↓, *IL6↓, *NF-kB↓, *p65↓, *Dose⇅,
4895- Sper,    Spermidine as a target for cancer therapy
- Review, Var, NA - Review, AD, NA
TumAuto↑, Apoptosis↑, OS↑, CRM↑, TumCG⇅, cardioP↑, cognitive↑, *Dose⇅,

Showing Research Papers: 1 to 4 of 4

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

ROS↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ETC↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

CRM↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 2,   BNIP3↝, 1,   Fas↑, 1,   FasL↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

JNK↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

HSP90↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

TumAuto↑, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

TumCG⇅, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   Hif1a↓, 1,   VEGF↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   Dose↝, 1,   RadioS↑, 1,  

Functional Outcomes(tgid=23) ⓘ

cardioP↑, 1,   cognitive↑, 1,   OS↑, 1,  
Total Targets: 21

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

GPx↑, 1,   GSH↑, 1,   ROS↓, 3,   ROS↑, 1,   ROS⇅, 1,   selenoP↑, 1,   SOD↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,  

Cell Death(tgid=5) ⓘ

Casp3↓, 1,   Casp9↓, 1,   Cyt‑c↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   MAPK↓, 1,   PI3K↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 2,   other↝, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

HSP70/HSPA5↑, 1,   HSPs↑, 1,  

Migration(tgid=13) ⓘ

MMP9↓, 1,  

Barriers & Transport(tgid=15) ⓘ

MMP↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 1,   COX2/PTGS2↓, 1,   CXCR4↓, 1,   IL17↓, 1,   IL18↓, 1,   IL1β↓, 1,   IL6↓, 2,   NF-kB↓, 1,   p65↓, 1,   PGE2↓, 1,   TNF-α↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 1,   Dose⇅, 4,   eff↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AST↓, 1,   CRP↓, 1,   IL6↓, 2,  

Functional Outcomes(tgid=23) ⓘ

hepatoP↑, 1,   neuroP↑, 1,   toxicity↑, 1,   toxicity↝, 1,  
Total Targets: 43

Scientific Paper Hit Count for: Dose, Dosage
1 Celastrol
1 Honokiol
1 Selenium NanoParticles
1 Spermidine
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:1114  State#:%  Dir#:3
  wNotes=0  sortOrder:rid,rpid

 

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