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5297- 5-HTP,    Targeting 5-HT Is a Potential Therapeutic Strategy for Neurodegenerative Diseases
- in-vivo, AD, NA - in-vivo, Park, NA
*other↝, *cognitive↑, *memory↑, *Ach↑,
5293- 5-HTP,    The Role of Tryptophan Metabolism in Alzheimer’s Disease
- in-vivo, AD, NA
*Sleep↑, *5HT↑, *memory↑, *other↝,
5292- 5-HTP,    Past, present, and future of serotonin-targeting therapeutics for Alzheimer’s disease: Perspectives from DNA methylation
- Review, AD, NA
*other↝, *cognitive↝,
5457- AF,    Clinical pharmacokinetics of oral and injectable gold compounds
- Human, Nor, NA
*BioAv↝, *Dose↝, *Half-Life↑, *BioAv↝, *other↝,
4562- AgNPs,  VitC,    Eco-friendly Synthesis of Silver Nanoparticles using Ascorbic Acid and its Optical Characterization
- Study, Var, NA
*other↑, *other↝,
4545- AgNPs,  VitC,  Citrate,    Ascorbic Acid-assisted Green Synthesis of Silver Nanoparticles: pH and Stability Study
- Study, Var, NA
*other↝, *other↝, *eff↑, *eff↑,
4586- AgNPs,    Tyndall-effect-enhanced supersensitive naked-eye determination of mercury (II) ions with silver nanoparticles
- Study, Var, NA
*other↝, *other↝,
4600- AgNPs,    Effects of particle size and coating on toxicologic parameters, fecal elimination kinetics and tissue distribution of acutely ingested silver nanoparticles in a mouse model
- in-vivo, Nor, NA
*Half-Life↝, *toxicity↓, *Dose↑, *other↝, *eff↝, *BioAv↓,
4585- AgNPs,    Tyndall-effect-based colorimetric assay with colloidal silver nanoparticles for quantitative point-of-care detection of creatinine using a laser pointer pen and a smartphone
- Study, Var, NA
*other↝,
4360- AgNPs,    Silver Nanoparticles as Real Topical Bullets for Wound Healing
- Study, Nor, NA
*other↝, *toxicity↓, *eff↑, *eff↑, *Inflam↓, *IL6↓, *TGF-β↑, *MMP9↓, *eff↑,
4359- AgNPs,    Antimicrobial Silver Nanoparticles for Wound Healing Application: Progress and Future Trends
- Review, Wounds, NA
*Bacteria↓, *eff↑, *other↝, *toxicity↓,
4367- AgNPs,    Effects of Prolonged Silver Nanoparticle Exposure on the Contextual Cognition and Behavior of Mammals
- in-vivo, Nor, NA
*other↝,
3270- ALA,    Alpha-lipoic acid as a new treatment option for Alzheimer's disease--a 48 months follow-up analysis
- Trial, AD, NA
*cognitive↑, *other↝, *neuroP↑, *IronCh↑, *ROS↓, *GSH↑,
3549- ALA,    Important roles of linoleic acid and α-linolenic acid in regulating cognitive impairment and neuropsychiatric issues in metabolic-related dementia
- Review, AD, NA
*Inflam↓, *other↝, *other↝, *neuroP↑, *BioAv↝, *adiP↑, *BBB↑, *Casp6↓, *Casp9↓, *TNF-α↓, *IL6↓, *IL1β↓, *ROS↓, *NO↓, *iNOS↓, *COX2/PTGS2↓, *JNK↓, *p‑NF-kB↓, *Aβ↓, *BP↓, *memory↑, *cAMP↑, *ERK↑, *Akt↑, cognitive?,
297- ALA,    Insights on the Use of α-Lipoic Acid for Therapeutic Purposes
- Review, BC, SkBr3 - Review, neuroblastoma, SK-N-SH - Review, AD, NA
PDH↑, TumCG↓, ROS↑, AMPK↑, EGR4↓, Half-Life↓, BioAv↝, *GSH↑, *IronCh↑, *ROS↓, *antiOx↑, *neuroP↑, *Ach↑, *lipid-P↓, *IL1β↓, *IL6↓, TumCP↓, FDG↓, Apoptosis↑, AMPK↑, mTOR↓, EGFR↓, TumCI↓, TumCMig↓, *memory↑, *BioAv↑, *BioAv↝, *other↓, *other↝, *Half-Life↓, *BioAv↑, *ChAT↑, *GlucoseCon↑,
4512- aLinA,  GLA,    Evening primrose oil: a comprehensive review of its bioactives, extraction, analysis, oil quality, therapeutic merits, and safety
- in-vivo, Nor, NA
*other↝,
4135- Alum,    Aluminum Should Now Be Considered a Primary Etiological Factor in Alzheimer's Disease
- Review, AD, NA
*Risk↑, *cognitive↓, *neuroP↓, *other↑, *other↝,
7395- Amla,    Tannoid principles of Emblica officinalis renovate cognitive deficits and attenuate amyloid pathologies against aluminum chloride induced rat model of Alzheimer's disease
- in-vivo, AD, NA
*AChE↓, *memory↑, *other↝,
6401- ANE,    Anethole and Its Role in Chronic Diseases
- Review, Var, NA - Review, PSA, NA
*BioAv↝, *other↝, CompStab↓, TNF-α↓, IL10↑, CXCR4↓, MMP2↓, MMP9↓, TIMP1↑, NF-kB↓, AP-1↓, STAT↓, JNK↓, ERK↓, MAPK↓, PI3K↓, Akt↓, JAK↓, *AntiDiabetic↓, *neuroP↑, *Imm↑, chemoP↑, *AntiThr↑, *AntiAg↑, *antiOx↑, *SOD↑, *GSH↑, *Wound Healing↑, chemoPv↑, *GSTs↑, *NF-kB↓,
2637- Api,    Apigenin Alleviates Endoplasmic Reticulum Stress-Mediated Apoptosis in INS-1 β-Cells
- in-vitro, Diabetic, NA
*other↝, *Insulin↑, ER Stress↓, *CHOP/DDIT3↓, *cl‑Casp3↓, *ROS↓, *Inflam↓, *TXNIP↓,
5413- ASA,    Drug Resistance and Pseudoresistance: An Unintended Consequence of Enteric Coating Aspirin
- Trial, Nor, NA
*cardioP↑, *other↝, *COX1↓, *TXA2↓,
5393- Ash,    Studies on oral bioavailability and first-pass metabolism of withaferin A in rats using LC-MS/MS and Q-TRAP
- in-vivo, Nor, NA
*BioAv↝, *other↝, *Half-Life↓,
5504- Ba,    Comparative Pharmacokinetics of Baicalin, Wogonoside, Baicalein and Wogonin in Plasma after Oral Administration of Pure Baicalin, Radix Scutellariae and Scutellariae-Paeoniae Couple Extracts in Normal and Ulcerative Colitis Rats
- in-vivo, Nor, NA
*BioAv↝, *other↝,
6495- BCP,    Beta-caryophyllene is a dietary cannabinoid
- Study, Nor, NA
*CB2 / CNR2↑, *other↝, *Inflam↓, *TNF-α↓, *IL1β↓, *ERK↓, *JNK↓,
4061- betaCar,  VitB12,  VitB6,  FA,  VitB3  Revisiting the Role of Vitamins and Minerals in Alzheimer’s Disease
- Review, AD, NA
*cognitive↑, *cognitive↑, *Inflam↓, *Hcy/homoC↓, *TNF-α↓, *other↝, *memory↑,
4621- Bor,    Boron
- Review, BPH, NA
*other↝, Risk↑, *Dose↑,
8363- Brocc,  SFN,    Synergistic strategies of sulforaphane biosynthesis and functional properties in broccoli sprouts powder obtained from sucrose stress modulation coupled with vacuum freeze-drying
- Study, Nor, NA
*BioAv↑, *other↝,
8360- Brocc,  SFN,    Heating decreases epithiospecifier protein activity and increases sulforaphane formation in broccoli
- Study, Nor, NA
*other↝,
8364- Brocc,  SFN,    Effect of sucrose and mannitol on the accumulation of health-promoting compounds and the activity of metabolic enzymes in broccoli sprouts
- Study, Nor, NA
*BioAv↑, *other↝,
8365- Brocc,  SFN,    Sucrose enhances the accumulation of anthocyanins and glucosinolates in broccoli sprouts
- Study, Nor, NA
*BioAv↑, *antiOx↑, *other↝,
5704- BRU,    Brusatol ameliorates psoriatic dyslipidemia by targeting IL-1β to restore AMPK-mediated lipid homeostasis
- in-vivo, PSA, HaCaT
*Inflam↓, *IL17↓, *TNF-α↓, *IL22↓, *STAT3↓, *other↝, *eff↑, *Dose?,
5710- Brut,    Recycling of Industrial Essential Oil Waste. Brutieridin and Melitidin, two Anticholesterolaemic Active Principles from Bergamot Albedo
- Review, Nor, NA
*other↝,
6556- BSB,    A Comprehensive Study of Therapeutic Applications of Chamomile
- Review, Nor, NA - Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, *antiOx↑, *AntiBio↑, *hepatoP↑, *AntiCan↑, *other↝, *toxicity↓, *Wound Healing↓, *Dose↝, *Dose↝, *eff↝, *ROS↓, *TNF-α↓, *IL6↓, *other↝, *AST↓, *ALAT↓, *antiAll↑,
9265- BTB,    Cooked Black Turtle Beans Ameliorate Insulin Resistance and Restore Gut Microbiota in C57BL/6J Mice on High-Fat Diets
- in-vivo, Nor, NA
*other↝, *LDL↓, *TG/TAG↓, *IL4↝, *IL5↝, *IFN-γ↝, *TNF-α↝, *IRes↓, *GutMicro↑,
5768- CAPE,    Neuroprotective Potential of Caffeic Acid Phenethyl Ester (CAPE) in CNS Disorders: Mechanistic and Therapeutic Insights
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*antiOx↑, *Inflam↑, *AntiCan↑, *NRF2↑, *GSK‐3β↑, *Akt↑, *PI3K↑, *ROS↓, *SOD↑, *GSH↑, *MDA↓, *tau↓, *neuroP↑, *memory↑, *AChE↓, *other↝, *lipid-P↓,
5926- CAR,    An Updated Review of Research into Carvacrol and Its Biological Activities
- Review, Nor, NA - Review, AD, NA - Review, Asthma, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↑, *toxicity↓, *Pain↓, *TRPV3↑, *NRF2↑, *Ca+2↑, *ATP↑, *5LO↓, *COX2/PTGS2↓, PGE2↓, *hepatoP↑, *AntiAg↑, *Diar↓, *cardioP↑, *other↝, *chemoPv↑, *cognitive↑, *AChE↓, *GastroP↑, *Synergy↑, *BChE↓, *CRP↓, *antiAll↑,
5943- Cela,    Celastrol: A Spectrum of Treatment Opportunities in Chronic Diseases
- Review, Arthritis, NA - Review, IBD, NA - Review, AD, NA - Review, Park, NA
*other↝, *other↝, *CRP↓, *eff↝, *other↑, *CXCR4↓, *IL1β↓, *IL6↓, *IL17↓, *IL18↓, *TNF-α↓, *MMP9↓, *PGE2↓, *COX1↓, *COX2/PTGS2↓, *PI3K↓, *Akt↓, *other↑, TumCCA↑, Apoptosis↑, ROS↑, JNK↑, TumAuto↑, Hif1a↓, BNIP3↝, HSP90↓, Fas↑, FasL↑, ETC↓, VEGF↓, angioG↓, RadioS↑, *neuroP↑, *HSP70/HSPA5↑, *ROS↓, *MMP↑, *Cyt‑c↓, *Casp3↓, *Casp9↓, *MAPK↓, *Dose⇅, *HSPs↑, BioAv↓, Dose↝,
6004- CGA,    Dose-response plasma appearance of coffee chlorogenic and phenolic acids in adults
- Human, Nor, NA
*BioAv↝, *other↝, BioAv↓,
5987- Chit,    Chitin, Chitosan, and Glycated Chitosan Regulate Immune Responses: The Novel Adjuvants for Cancer Vaccine
- Review, Var, NA
other↝, other↝, *Weight↝, *toxicity↓, *Bacteria↓, *BioAv↑, DDS↑, *Wound Healing↑, *other↝, *Imm↑, eff↑, *BioAv↝, *BioAv↑, eff↑, NK cell↑, IL2↑, IFN-γ↑, IL10↑,
5991- Chit,    Chitosan-Based Nanoencapsulated Essential Oils: Potential Leads against Breast Cancer Cells in Preclinical Studies
- Review, BC, NA
*other↝, *BioAv↓, eff↑, toxicity↓, eff↑, TumCD↑, Half-Life↑, selectivity↑, EPR↑, ROS↑, Apoptosis↑, eff↑,
4490- Chit,  FA,    Chitosan Nanoparticle-Based Drug Delivery Systems: Advances, Challenges, and Future Perspectives
- Review, Var, NA
EPR↑, *BioAv↑, *CompStab↑, *other↝, *Insulin↑, *Bacteria↓, eff↑, ChemoSen↑,
6065- CHL,    Chemoprevention with chlorophyllin in individuals exposed to dietary aflatoxin
- Review, HCC, NA
*eff↑, *chemoPv↑, *other↝,
6108- Chol,    Trimethylamine-N-Oxide (TMAO) as a Rising-Star Metabolite: Implications for Human Health
- Review, Nor, NA - Review, AD, NA
*TMAO↑, *ROS↑, *NADPH↑, *Ca+2↑, *AntiAg↓, *cognitive↓, *TJ↓, *CLDN1↓, *ZO-1↓, *Inflam↑, *NLRP3↑, *ER Stress↑, *cognitive↓, *Dose↝, *eff↑, *other↝, *other↝, *other↝,
7406- Chy,    Antiamnesic activity of an ayurvedic formulation chyawanprash in mice
- in-vivo, AD, NA
*Dose↝, *memory↑, *TBARS↓, *GSH↑, *ROS↓, *cognitive↑, *AntiAge↑, *hepatoP↑, *antiOx↑, *LDL↓, *Inflam↓, *other↝, *AChE∅,
6169- Cin,    Unlocking the Power of Cinnamon: A Detailed Review of Cinnamon Therapeutic Effects in Chronic Disease Management
- Review, Var, NA - Review, Diabetic, NA - Review, AD, NA - Review, IBD, NA
*neuroP↑, *AntiDiabetic↑, *tau↓, *Aβ↓, *antiOx↑, *Inflam↓, *ROS↓, *MDA↓, *GSH↓, *cardioP↑, *LDL↓, *HDL↑, *other↝, *TNF-α↓, *IL6↓, *MPO↓, *TLR4↓, *GutMicro↑, *lipid-P↓, *Wound Healing↑,
8995- Citicoline,    Neuroprotection afforded by prior citicoline administration in experimental brain ischemia: effects on glutamate transport
- in-vivo, Stroke, NA
*Dose↝, *Stroke↓, *other↝, *ATP↑, *neuroP↑,
8992- Citicoline,    Citicoline: neuroprotective mechanisms in cerebral ischemia
- Review, Stroke, NA
*Stroke↓, *other↝, *other↝, *other?, *GSH↑, *GPx↑, *lipid-P↓, *ATPase↑, *Ach↑,
8994- Citicoline,    Double-blind placebo-controlled study with citicoline in APOE genotyped Alzheimer's disease patients. Effects on cognitive performance, brain bioelectrical activity and cerebral perfusion
- Trial, AD, NA
*Dose?, *cognitive↑, *BloodF↑, *other↝, *IL1β↓, *eff↑,
3994- CoQ10,  Se,    Coenzyme Q10 Supplementation in Aging and Disease
- Review, AD, NA - Review, Park, NA
*AntiAge↑, *cardioP↑, *Inflam↓, *antiOx↑, *lipid-P↓, *QoL↑, *neuroP↑, *Dose↝, *BP↓, *IGF-1↑, *IGFBP1↑, *Synergy↑, *LDL↓, *HDL↑, *Synergy↑, *other↑, *RenoP↑, *ROS↓, *TNF-α↓, *IL6↓, *other↝, *other∅,
3997- CoQ10,    Coenzyme Q and Its Role in the Dietary Therapy against Aging
- Review, AD, NA
*AntiAge↑, *Inflam↓, *antiOx↑, *Apoptosis↓, *BioAv↑, *other↝, *cognitive↑, *DNAdam↓, *ER Stress↓,

Showing Research Papers: 1 to 50 of 163
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 163

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

GSH↓, 2,   ROS↑, 10,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ETC↓, 1,   OCR↓, 1,   PDH↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 2,   ATP↓, 2,   FDG↓, 1,   Glycolysis↓, 3,   HK2↓, 1,   SREBP2↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 7,   BAX↑, 2,   Bcl-2↓, 2,   BNIP3↝, 1,   Casp3↑, 4,   Casp9↑, 1,   cFLIP↓, 1,   Cyt‑c↑, 2,   Fas↑, 2,   FasL↑, 2,   IAP1↓, 1,   Necroptosis↑, 1,   p38↑, 1,   Pyro↑, 1,   survivin↓, 2,   TumCD↓, 1,   TumCD↑, 1,   XIAP↓, 2,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 6,   EGFR↓, 3,   ERK↓, 3,   ERK↑, 1,   HER2/EBBR2↓, 3,   JAK↓, 1,   JNK↓, 2,   JNK↑, 1,   MAPK↓, 2,   mTOR↓, 4,   P70S6K↓, 2,   PI3K↓, 5,   PKCδ↓, 2,   RAS↓, 1,   RIP1↓, 1,   Sp1/3/4↓, 2,   STAT↓, 1,   STAT3↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↝, 6,   tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1,   eIF2α↑, 1,   ER Stress↓, 1,   ER Stress↑, 1,   HSP90↓, 2,   PERK↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

TumAuto↑, 4,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 1,   P53↑, 1,   cl‑PARP↑, 1,   Telomerase↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CDK4↓, 1,   CDK6↓, 1,   cycD1/CCND1↑, 1,   P21↑, 2,   TumCCA↑, 5,   WEE1↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

p‑4E-BP1↓, 1,   TumCG↓, 1,   TumCP↓, 7,   Wnt↓, 1,  

Migration(tgid=13) ⓘ

AntiAg?, 1,   AP-1↓, 2,   Ca+2↑, 1,   Cofilin↓, 1,   EMT↓, 2,   ITGB1↓, 1,   ITGB6↓, 1,   LIMK2↓, 1,   MET↓, 1,   MMP2↓, 3,   MMP9↓, 3,   MMPs↓, 2,   Rho↝, 1,   ROCK1↓, 1,   TGF-β↓, 2,   TIMP1↑, 1,   TumCI↓, 5,   TumCMig↓, 5,   TumMeta↓, 4,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 4,   EGR4↓, 1,   Hif1a↓, 2,   VEGF↓, 2,  

Barriers & Transport(tgid=15) ⓘ

EPR↑, 3,   GLUT1↓, 1,   MMP↓, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD25+↑, 1,   CD4+↑, 1,   CXCR4↓, 1,   DR4↑, 1,   FOXP3↑, 1,   IFN-γ↑, 2,   IL1↑, 1,   IL10↑, 2,   IL12↑, 1,   IL2↑, 1,   Imm↝, 1,   NF-kB↓, 5,   NK cell↑, 1,   PD-L1↓, 1,   PGE2↓, 1,   PSA↓, 1,   T-Cell↑, 1,   TNF-α↓, 3,   TNF-α↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 1,   BioAv↓, 2,   BioAv↑, 1,   BioAv↝, 1,   chemoR↓, 1,   ChemoSen↑, 6,   CompStab↓, 1,   CYP1A1↑, 1,   CYP1A2↑, 1,   CYP2A3/CYP2A6↓, 1,   CYP2E1↑, 1,   CYP3A4↓, 1,   DDS↑, 1,   Dose↓, 1,   Dose↝, 2,   eff↑, 12,   Half-Life↓, 1,   Half-Life↑, 1,   P-gp/ABCB1↓, 1,   P450↓, 1,   RadioS↑, 2,   selectivity↑, 8,   Synergy↑, 5,  

Clinical Biomarkers(tgid=22) ⓘ

EGFR↓, 3,   HER2/EBBR2↓, 3,   PD-L1↓, 1,   PSA↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 6,   AntiTum↑, 2,   chemoP↑, 2,   chemoPv↑, 2,   cognitive?, 1,   Risk↓, 3,   Risk↑, 1,   toxicity↓, 2,   toxicity↝, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Api↑, 1,  
Total Targets: 154

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

4-HNE↓, 1,   antiOx↓, 1,   antiOx↑, 33,   Catalase↑, 4,   Fenton↓, 1,   GPx↑, 2,   GPx1↑, 2,   GPx4↑, 2,   GSH↓, 1,   GSH↑, 12,   GSTs↑, 1,   H2O2↓, 1,   HDL↓, 1,   HDL↑, 2,   HDL∅, 1,   HNE↓, 1,   HO-1↑, 5,   hyperG↝, 1,   Iron↓, 1,   Keap1↓, 1,   lipid-P↓, 11,   MDA↓, 5,   MPO↓, 1,   NRF2↑, 9,   RNS↓, 2,   ROS?, 1,   ROS↓, 29,   ROS↑, 2,   ROS⇅, 1,   ROS∅, 1,   selenoP↑, 2,   SOD↑, 4,   SOD1↑, 4,   SOD2↑, 1,   TBARS↓, 1,   VitC↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 3,   Zn2+↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compV↑, 1,   Insulin↓, 1,   Insulin↑, 2,   Insulin↝, 1,   mitResp↓, 1,   mitResp↑, 1,   OCR↑, 1,   OXPHOS↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 1,   adiP↑, 1,   ALAT↓, 4,   ATP↑, 4,   cAMP↑, 1,   Cit/L-Cit↝, 1,   G6PD↑, 1,   glucose↝, 1,   GlucoseCon↑, 1,   Glycolysis↑, 1,   GSK‐3β↓, 1,   GSK‐3β↑, 1,   HK2↑, 1,   LDL↓, 9,   NADPH↑, 2,   ODC1↝, 1,   PFKL↑, 1,   PFKM↑, 1,   PKM2↑, 1,   polyA↝, 1,   SCFAs∅, 1,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 3,   BAX↑, 1,   Bcl-2↑, 1,   Bcl-xL↓, 1,   Casp3↓, 2,   cl‑Casp3↓, 2,   proCasp3↓, 1,   Casp6↓, 1,   cl‑Casp8↓, 1,   Casp9↓, 2,   Cyt‑c↓, 1,   Cyt‑c↑, 1,   Ferroptosis↓, 1,   iNOS↓, 3,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   Akt↑, 3,   CREB↑, 1,   ERK↓, 1,   ERK↑, 2,   JNK↓, 2,   MAPK↓, 2,   p‑MEK↑, 1,   PI3K↓, 1,   PI3K↑, 1,   PKCδ↑, 2,   RIP1↓, 1,   STAT3↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   HDAC↓, 1,   other?, 4,   other↓, 3,   other↑, 13,   other⇅, 1,   other↝, 198,   other∅, 1,   tumCV↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 2,   ER Stress↓, 2,   ER Stress↑, 1,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↑, 1,   HSPs↑, 1,   UPR↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,   LC3II↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 2,   P53↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,   P21↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

GH↑, 1,   IGF-1↑, 1,   IGFBP1↑, 1,   neuroG↑, 1,   TumCG↓, 1,   Zn2+↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↓, 1,   AntiAg↑, 5,   ATPase↑, 1,   Ca+2↓, 1,   Ca+2↑, 2,   Ca+2↝, 1,   cal2↓, 1,   COL1↓, 1,   MMP-10↓, 1,   MMP2↓, 1,   MMP3↓, 1,   MMP9↓, 3,   proline↝, 1,   p‑SMAD2↓, 1,   p‑SMAD3↓, 1,   TGF-β↓, 1,   TGF-β↑, 1,   TIMP1↑, 1,   TumCMig↑, 1,   TXNIP↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   E-sel↓, 1,   Hif1a↓, 1,   Hif1a↝, 1,   NO↓, 2,   NO↑, 1,   TXA2↓, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 2,   BBB↑, 2,   BBB↝, 3,   CellMemb↑, 2,   CLDN1↓, 1,   CX43/GJA1↑, 1,   GastroP↑, 3,   GLUT1↑, 2,   GLUT3↑, 1,   MMP↑, 2,   MUC5AC↓, 1,   THBD↑, 1,   TJ↓, 1,   TRPV3↑, 1,   ZO-1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CB2 / CNR2↑, 1,   CCL11↓, 1,   COX1↓, 3,   COX2/PTGS2↓, 7,   CXCR4↓, 1,   IFN-γ↓, 1,   IFN-γ↝, 1,   IL10↑, 1,   IL17↓, 3,   IL18↓, 1,   IL1β↓, 11,   IL2↓, 1,   IL22↓, 1,   IL23↓, 1,   IL4↑, 1,   IL4↝, 1,   IL5↝, 1,   IL6↓, 14,   IL8↓, 2,   Imm↑, 9,   Inflam?, 1,   Inflam↓, 45,   Inflam↑, 2,   MCP1/CCL2↓, 1,   NF-kB↓, 7,   p‑NF-kB↓, 1,   NK cell↑, 1,   NLRP3↓, 2,   NLRP3↑, 1,   PGE2↓, 1,   TLR3↓, 1,   TLR4↓, 2,   TNF-α↓, 15,   TNF-α↝, 1,  

Cellular Microenvironment(tgid=17) ⓘ

pH↑, 1,   pH↝, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5-AR↓, 1,   5HT↑, 1,   Ach↑, 7,   AChE↓, 6,   AChE∅, 1,   BChE↓, 1,   BDNF↑, 1,   BrainVol↑, 1,   BrainVol↝, 1,   BrainVol∅, 1,   CARTPT↑, 1,   ChAT↑, 1,   MAOA↓, 1,   MAOB↓, 1,   NGF↑, 1,   TrkB↓, 1,  

Protein Aggregation(tgid=19) ⓘ

APP↓, 1,   Aβ↓, 10,   Aβ↑, 1,   BACE/β-secretase↓, 1,   tau↓, 8,   p‑tau↓, 5,   XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CYP19↓, 1,   GPER↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 4,   BioAv↑, 25,   BioAv↝, 16,   BioEnh↑, 1,   CompStab↑, 2,   CYP2C19↓, 1,   CYP2C9↓, 1,   CYP2E1↓, 1,   Dose?, 3,   Dose↓, 3,   Dose↑, 3,   Dose⇅, 1,   Dose↝, 37,   eff↓, 3,   eff↑, 26,   eff↝, 4,   eff∅, 1,   Half-Life↓, 2,   Half-Life↑, 3,   Half-Life↝, 7,   Synergy↑, 7,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 4,   AST↓, 3,   BloodF↑, 1,   BP↓, 5,   Calcium↝, 1,   CRP↓, 2,   Hcy/homoC↓, 5,   Hcy/homoC↝, 1,   IL6↓, 14,   IRes↓, 2,   TC↓, 2,   TG/TAG↓, 1,   TMAO↑, 1,   UFR?, 1,   Verbal↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 4,   antiAll↑, 4,   AntiArt↑, 3,   AntiCan↑, 7,   antiCG↑, 1,   AntiDiabetic↓, 1,   AntiDiabetic↑, 7,   BowelM↑, 1,   cardioP↑, 8,   chemoPv↑, 2,   cognitive↓, 3,   cognitive↑, 35,   cognitive↝, 2,   cognitive?, 1,   cognitive∅, 1,   DCR∅, 1,   diuretic↑, 1,   fatigue↓, 1,   hepatoP↓, 1,   hepatoP↑, 9,   IPSS↓, 1,   IPSS↝, 1,   memory↑, 23,   Mood↑, 3,   motorD↑, 2,   neuroP↓, 1,   neuroP↑, 31,   Obesity↓, 4,   ORR∅, 1,   Pain↓, 3,   PFS∅, 1,   QoL↑, 3,   radioP↑, 1,   RenoP↑, 2,   Risk↓, 12,   Risk↑, 2,   Risk↝, 1,   Risk∅, 1,   Sleep↑, 6,   Stress↓, 2,   Stroke↓, 4,   toxicity↓, 22,   toxicity↑, 1,   toxicity↝, 5,   Weight↝, 1,   Wound Healing↓, 1,   Wound Healing↑, 3,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 8,   AntiFungal↑, 1,   AntiP↑, 1,   AntiViral↑, 2,   Bacteria↓, 15,   Diar↓, 1,   GutMicro↑, 8,   GutMicro↝, 3,   GutMicro∅, 1,   Inf↓, 1,   Sepsis↓, 3,  

Ingredients & Constituents(tgid=25) ⓘ

Api↑, 1,   CA↑, 1,   Catechins↑, 1,   FA↑, 1,   Fibre↑, 1,   GA↑, 1,   Ingr↑, 3,   Ingr↝, 1,   LT↑, 1,   Myr↑, 1,   Phen↑, 1,   Poly↑, 1,   QC↑, 2,  
Total Targets: 335

Scientific Paper Hit Count for: other, other
10 Folic Acid, Vit B9
9 Silver-NanoParticles
8 Gamma-aminobutyric acid
7 Magnetic Fields
7 Selenium NanoParticles
6 Vitamin B12
5 Vitamin B5,Pantothenic Acid
4 Vitamin B6,pyridoxine
4 Broccoli
4 Sulforaphane (mainly Broccoli)
4 Flaxseed/Linseed
3 5-Hydroxytryptophan
3 Vitamin C (Ascorbic Acid)
3 Alpha-Lipoic-Acid
3 chitosan
3 Citicoline, CDP-Choline
3 Vitamin E
3 Potassium
3 Selenite (Sodium)
3 Vitamin B1/Thiamine
3 Vitamin D3
2 Aluminum
2 Apigenin (mainly Parsley)
2 Coenzyme Q10
2 Date Fruit Extract
2 Emodin
2 SDG/lignans
2 phytic acid, Inositol hexakisphosphate
2 Kaempferol
2 Methyl salicylate / Sweet Birch oil
2 Magnetic Field Rotating
2 Nasturtium, Indian Cress
2 probiotics
2 Taurine
1 Auranofin
1 Citric Acid
1 alpha Linolenic acid
1 γ-linolenic acid (Borage Oil)
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Anethole/trans-Anethole
1 Aspirin
1 Ashwagandha(Withaferin A)
1 Baicalein
1 Beta-Caryophyllene
1 beta-carotene(VitA)
1 Vitamin B3,Niacin
1 Boron
1 brusatol
1 Bruteridin(bergamot juice)
1 α-Bisabolol / Chamomile oil
1 Black turtle bean
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Carvacrol
1 Celastrol
1 Chlorogenic acid
1 Chlorophyllin
1 Choline
1 Chyawanprash
1 Cinnamon
1 Selenium
1 Cranberry
1 Cysteamine
1 Docosahexaenoic Acid
1 Dihydrocaffeic Acid
1 diet Fermented Foods
1 Dipyridamole
1 Dimethyl Sulfoxide
1 Dandelion Root
1 Ellagic acid
1 Ginkgo biloba-EGb 761
1 EGCG (Epigallocatechin Gallate)
1 Silicic Acid
1 Flickering Light Stimulation
1 Shilajit/Fulvic Acid
1 Ginseng
1 Grapeseed extract
1 Hydrogen Gas
1 Hydroxycinnamic-acid
1 Hibiscus sabdariffa
1 Inositol
1 Inulin Prebiotic
1 Isovitexin
1 L-ornithine
1 L-Theanine
1 Licochalcone A
1 Luteolin
1 Myricetin
1 Quercetin
1 Methylene blue
1 Magnolol
1 Metformin
1 Mushroom Lion’s Mane, Hericium erinaceus
1 Mushroom Maitake
1 Isothiocyanates
1 Nimbolide
1 None
1 Oregano
1 Peppermint
1 Phenethyl isothiocyanate
1 Phenolic Acids
1 Piperlongumine
1 Psyllium husk
1 Pumpkin Seed Oil / Cucurbita pepo
1 Tamsulosin
1 Rosmarinic acid
1 Aromatherapy
1 Sesamin
1 Shankhpushpi
1 Terpinen-4-ol / Tea Tree Oil
1 Thyme
1 Thymoquinone
1 Exercise
1 Vitamin K2
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:767  State#:%  Dir#:4
  wNotes=0  sortOrder:rid,rpid

 

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