ROCK1 Cancer Research Results

ROCK1, Rho-associated coiled-coil containing protein kinase 1: Click to Expand ⟱

Source:

Type:

ROCK1 (Rho-associated coiled-coil containing protein kinase 1)
– ROCK1 is a serine/threonine kinase and a major effector of the Rho GTPase signaling pathway.

– Elevated expression of ROCK1 has been observed in various cancers, including breast, prostate, lung, colorectal, and gastric cancers.

– In many tumors, ROCK1 overexpression correlates with increased cell motility, invasion, and metastatic potential.

NA, Not Available: Click to Expand ⟱

none (reserved)

Scientific Papers found: Click to Expand⟱

3395-

ART/DHA,

Artesunate Induces Ferroptosis in Hepatic Stellate Cells and Alleviates Liver Fibrosis via the ROCK1/ATF3 Axis

in-vitro,

NA,

HSC-T6

 Liver Fibrosis LX2

*Ferroptosis↑, *GSH↓, *ROCK1↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Total Targets: 0

Pathway results for Effect on Normal Cells:

Redox & Oxidative Stress ⓘ

Ferroptosis↑, 1, GSH↓, 1,

Cell Death ⓘ

Ferroptosis↑, 1,

Migration ⓘ

ROCK1↓, 1,
Total Targets: 4

Scientific Paper Hit Count for: ROCK1, Rho-associated coiled-coil containing protein kinase 1

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells