Aβ Cancer Research Results

Aβ, Aβ aggregation: Click to Expand ⟱
Source:
Type:
Beta-Amyloid (Aβ): In Alzheimer’s disease, Aβ peptides tend to misfold and aggregate into oligomers and fibrils.
NA, Not Available: Click to Expand ⟱
none (reserved)
Scientific Papers found: Click to Expand⟱
6625- Cic,  Ech,    Chicoric acid supplementation prevents systemic inflammation-induced memory impairment and amyloidogenesis via inhibition of NF-κB
- in-vivo, NA, NA
*memory↑, *Aβ↓, *BACE↓, *MAPK↓, *NF-kB↓, *NF-kB↓, *iNOS↓, *COX2↓, *IL1β↓, *TNF-α↓, *BDNF∅, *MMPs↓,
3810- mushLions,    Key Mechanisms and Potential Implications of Hericium erinaceus in NLRP3 Inflammasome Activation by Reactive Oxygen Species during Alzheimer’s Disease
- Review, NA, NA
*neuroP↑, *p‑tau↓, *APP↓, *Aβ↓, *ROS↓, *Inflam↓, *NLRP3↓,
3809- mushLions,    The Monkey Head Mushroom and Memory Enhancement in Alzheimer's Disease
- Review, NA, NA
*cognitive↑, *Apoptosis↓, *Aβ↓, *AChE↓, *BACE↓,
3028- RosA,    Network pharmacology mechanism of Rosmarinus officinalis L.(Rosemary) to improve cell viability and reduces apoptosis in treating Alzheimer’s disease
- in-vitro, AD, HT22 - in-vivo, NA, NA
*Aβ↓, *Apoptosis↓, *antiOx↑, *neuroP↑, *eff↑, *IGF-1↑, *MMP9↑, *Src↓, *MAPK↓, *MMP↑,
4190- Sesame,    Sesame Seeds: A Nutrient-Rich Superfood
- Review, NA, NA
*antiOx↑, *LDL↓, *Aβ↓, *TNF-α↓, *SOD↑, *SIRT1↑, *Catalase↑, *GSH↑, *MDA↓, *GSTs↑, *IL4↑, *GPx↑, *COX2↓, *PGE2↓, *NO↓, CDK2↑, COX2↑, MMP9↑, ICAM-1↓, *BDNF↑, *PPARγ↑, *AChE↓, *Inflam↓, *HO-1↑, *NF-kB↓, *ROS↓,
4188- VitK2,    Vitamin K2 protects against aluminium chloride-mediated neurodegeneration
- in-vivo, NA, NA
*BDNF↑, *Aβ↓, *cognitive↑, *Ach↑, *Inflam↓,

Showing Research Papers: 1 to 6 of 6

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 6

Pathway results for Effect on Cancer / Diseased Cells:


Cell Cycle & Senescence ⓘ

CDK2↑, 1,  

Migration ⓘ

MMP9↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↑, 1,   ICAM-1↓, 1,  
Total Targets: 4

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 2,   Catalase↑, 1,   GPx↑, 1,   GSH↑, 1,   GSTs↑, 1,   HO-1↑, 1,   MDA↓, 1,   ROS↓, 2,   SOD↑, 1,  

Mitochondria & Bioenergetics ⓘ

MMP↑, 1,  

Core Metabolism/Glycolysis ⓘ

LDL↓, 1,   PPARγ↑, 1,   SIRT1↑, 1,  

Cell Death ⓘ

Apoptosis↓, 2,   iNOS↓, 1,   MAPK↓, 2,  

Transcription & Epigenetics ⓘ

Ach↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

IGF-1↑, 1,   Src↓, 1,  

Migration ⓘ

APP↓, 1,   MMP9↑, 1,   MMPs↓, 1,  

Angiogenesis & Vasculature ⓘ

NO↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 2,   IL1β↓, 1,   IL4↑, 1,   Inflam↓, 3,   NF-kB↓, 3,   PGE2↓, 1,   TNF-α↓, 2,  

Synaptic & Neurotransmission ⓘ

AChE↓, 2,   BDNF↑, 2,   BDNF∅, 1,   p‑tau↓, 1,  

Protein Aggregation ⓘ

Aβ↓, 6,   BACE↓, 2,   NLRP3↓, 1,  

Drug Metabolism & Resistance ⓘ

eff↑, 1,  

Functional Outcomes ⓘ

cognitive↑, 2,   memory↑, 1,   neuroP↑, 2,  
Total Targets: 41

Scientific Paper Hit Count for: Aβ, Aβ aggregation
2 Mushroom Lion’s Mane
1 Cichoric acid / Chicoric acid
1 Echinacea
1 Rosmarinic acid
1 Sesame seeds and Oil
1 Vitamin K2
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:0  Cells:%  prod#:%  Target#:1333  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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