Aβ Cancer Research Results
Aβ, Aβ aggregation: Click to Expand ⟱
| Source: |
| Type: |
Beta-Amyloid (Aβ): In Alzheimer’s disease, Aβ peptides tend to misfold and aggregate into oligomers and fibrils.
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NA, Not Available: Click to Expand ⟱
Scientific Papers found: Click to Expand⟱
*neuroP↑, *p‑tau↓, *APP↓, *Aβ↓, *ROS↓, *Inflam↓, *NLRP3↓,
*cognitive↑, *Apoptosis↓, *Aβ↓, *AChE↓, *BACE↓,
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in-vitro, |
AD, |
HT22 |
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in-vivo, |
NA, |
NA |
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*Aβ↓, *Apoptosis↓, *antiOx↑, *neuroP↑, *eff↑, *IGF-1↑, *MMP9↑, *Src↓, *MAPK↓, *MMP↑,
*antiOx↑, *LDL↓, *Aβ↓, *TNF-α↓, *SOD↑, *SIRT1↑, *Catalase↑, *GSH↑, *MDA↓, *GSTs↑, *IL4↑, *GPx↑, *COX2↓, *PGE2↓, *NO↓, CDK2↑, COX2↑, MMP9↑, ICAM-1↓, *BDNF↑, *PPARγ↑, *AChE↓, *Inflam↓, *HO-1↑, *NF-kB↓, *ROS↓,
*BDNF↑, *Aβ↓, *cognitive↑, *Ach↑, *Inflam↓,
Showing Research Papers: 1 to 5 of 5
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5
Pathway results for Effect on Cancer / Diseased Cells:
Cell Cycle & Senescence ⓘ
CDK2↑, 1,
Migration ⓘ
MMP9↑, 1,
Immune & Inflammatory Signaling ⓘ
COX2↑, 1, ICAM-1↓, 1,
Total Targets: 4
Pathway results for Effect on Normal Cells:
Redox & Oxidative Stress ⓘ
antiOx↑, 2, Catalase↑, 1, GPx↑, 1, GSH↑, 1, GSTs↑, 1, HO-1↑, 1, MDA↓, 1, ROS↓, 2, SOD↑, 1,
Mitochondria & Bioenergetics ⓘ
MMP↑, 1,
Core Metabolism/Glycolysis ⓘ
LDL↓, 1, PPARγ↑, 1, SIRT1↑, 1,
Cell Death ⓘ
Apoptosis↓, 2, MAPK↓, 1,
Transcription & Epigenetics ⓘ
Ach↑, 1,
Proliferation, Differentiation & Cell State ⓘ
IGF-1↑, 1, Src↓, 1,
Migration ⓘ
APP↓, 1, MMP9↑, 1,
Angiogenesis & Vasculature ⓘ
NO↓, 1,
Immune & Inflammatory Signaling ⓘ
COX2↓, 1, IL4↑, 1, Inflam↓, 3, NF-kB↓, 1, PGE2↓, 1, TNF-α↓, 1,
Synaptic & Neurotransmission ⓘ
AChE↓, 2, BDNF↑, 2, p‑tau↓, 1,
Protein Aggregation ⓘ
Aβ↓, 5, BACE↓, 1, NLRP3↓, 1,
Drug Metabolism & Resistance ⓘ
eff↑, 1,
Functional Outcomes ⓘ
cognitive↑, 2, neuroP↑, 2,
Total Targets: 36
Scientific Paper Hit Count for: Aβ, Aβ aggregation
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:0 Cells:% prod#:% Target#:1333 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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