BUN Cancer Research Results

BUN, blood urea nitrogen: Click to Expand ⟱
Source:
Type:
Blood urea nitrogen (BUN) is a measure of the amount of nitrogen in your blood that comes from the waste product urea. Urea is produced in the liver as a byproduct of protein metabolism and is normally excreted by the kidneys.
-BUN is commonly used as one indicator of kidney function. Elevated BUN levels may suggest that the kidneys are not effectively clearing urea from the blood.
NA, Not Available: Click to Expand ⟱
none (reserved)
Scientific Papers found: Click to Expand⟱
3456- ALA,    Renal-Protective Roles of Lipoic Acid in Kidney Disease
- Review, NA, NA
*RenoP↑, *ROS↓, *antiOx↑, *Inflam↓, *Sepsis↓, *IronCh↑, *BUN↓, *creat↓, *TNF-α↓, *IL6↓, *IL1β↓, *MDA↓, *NRF2↑, *HO-1↑, *NQO1↑, *chemoP↑, *eff↑, *NF-kB↓,
3170- Ash,    Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms
- in-vitro, Nor, NRK52E - in-vivo, NA, NA
*RenoP↑, *hepatoP↑, *creat↓, *BUN↓, *uricA↓, *Apoptosis↓, *α-SMA↓,
3313- SIL,    Silymarin attenuates post-weaning bisphenol A-induced renal injury by suppressing ferroptosis and amyloidosis through Kim-1/Nrf2/HO-1 signaling modulation in male Wistar rats
- in-vivo, NA, NA
*NRF2↑, *HO-1↑, *creat↓, *BUN↓, *RenoP↑, *MDA↓, *TNF-α↓, *IL1β↓, *Cyt‑c↓, *Casp3↓, *GSTs↓, *GSH↑, *GPx4↑, *SOD↑, *GSR↓, *Ferroptosis↓,

Showing Research Papers: 1 to 3 of 3

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,   Ferroptosis↓, 1,   GPx4↑, 1,   GSH↑, 1,   GSR↓, 1,   GSTs↓, 1,   HO-1↑, 2,   MDA↓, 2,   NQO1↑, 1,   NRF2↑, 2,   ROS↓, 1,   SOD↑, 1,   uricA↓, 1,  

Metal & Cofactor Biology ⓘ

IronCh↑, 1,  

Core Metabolism/Glycolysis ⓘ

BUN↓, 3,  

Cell Death ⓘ

Apoptosis↓, 1,   Casp3↓, 1,   Cyt‑c↓, 1,   Ferroptosis↓, 1,  

Migration ⓘ

α-SMA↓, 1,  

Immune & Inflammatory Signaling ⓘ

IL1β↓, 2,   IL6↓, 1,   Inflam↓, 1,   NF-kB↓, 1,   TNF-α↓, 2,  

Drug Metabolism & Resistance ⓘ

eff↑, 1,  

Clinical Biomarkers ⓘ

creat↓, 3,   IL6↓, 1,  

Functional Outcomes ⓘ

chemoP↑, 1,   hepatoP↑, 1,   RenoP↑, 3,  

Infection & Microbiome ⓘ

Sepsis↓, 1,  
Total Targets: 32

Scientific Paper Hit Count for: BUN, blood urea nitrogen
1 Alpha-Lipoic-Acid
1 Ashwagandha(Withaferin A)
1 Silymarin (Milk Thistle) silibinin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:0  Cells:%  prod#:%  Target#:1338  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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