RNS Cancer Research Results

RNS, reactive nitrogen species: Click to Expand ⟱
Source:
Type:
Reactive nitrogen species (RNS) are chemically reactive molecules that contain nitrogen and can play significant roles in cellular signaling and homeostasis. Like reactive oxygen species (ROS), RNS can have both beneficial and detrimental effects in the context of cancer.


NA, Not Available: Click to Expand ⟱
none (reserved)

Scientific Papers found: Click to Expand⟱
236- AL,    Allicin: Chemistry and Biological Properties
- Analysis, NA, NA
GSH↓, Bacteria↓, LDL↓, ROS↑, NRF2↑, cognitive↑, memory↑, BP↓, RNS↓,
3201- EGCG,    Epigallocatechin Gallate (EGCG): Pharmacological Properties, Biological Activities and Therapeutic Potential
- Review, NA, NA
*AntiCan↑, *cardioP↑, *neuroP↑, *BioAv↝, *BioAv↓, *BioAv↓, *Dose↝, *Half-Life↝, *BioAv↑, *BBB↑, *hepatoP↓, *other↓, *Inflam↓, *NF-kB↓, *AP-1↓, *iNOS↓, *COX2↓, *ROS↓, *RNS↓, *IL8↓, *JAK↓, *PDGFR-BB↓, *IGF-1R↓, *MMP2↓, *P53↓, *NRF2↑, *TNF-α↓, *IL6↓, *E2Fs↑, *SOD1↑, *SOD2↑, Casp3↑, Cyt‑c↑, PARP↑, DNMTs↓, Telomerase↓, Hif1a↓, MMPs↓, BAX↑, Bak↑, Bcl-2↓, Bcl-xL↓, P53↑, PTEN↑, TumCP↓, MAPK↓, HGF/c-Met↓, TIMP1↑, HDAC↓, MMP9↓, uPA↓, GlutMet↓, ChemoSen↑, chemoP↑,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

GSH↓, 1,   NRF2↑, 1,   RNS↓, 1,   ROS↑, 1,  

Core Metabolism/Glycolysis

GlutMet↓, 1,   LDL↓, 1,  

Cell Death

Bak↑, 1,   BAX↑, 1,   Bcl-2↓, 1,   Bcl-xL↓, 1,   Casp3↑, 1,   Cyt‑c↑, 1,   HGF/c-Met↓, 1,   MAPK↓, 1,   Telomerase↓, 1,  

DNA Damage & Repair

DNMTs↓, 1,   P53↑, 1,   PARP↑, 1,  

Proliferation, Differentiation & Cell State

HDAC↓, 1,   PTEN↑, 1,  

Migration

MMP9↓, 1,   MMPs↓, 1,   TIMP1↑, 1,   TumCP↓, 1,   uPA↓, 1,  

Angiogenesis & Vasculature

Hif1a↓, 1,  

Drug Metabolism & Resistance

ChemoSen↑, 1,  

Clinical Biomarkers

BP↓, 1,  

Functional Outcomes

chemoP↑, 1,   cognitive↑, 1,   memory↑, 1,  

Infection & Microbiome

Bacteria↓, 1,  
Total Targets: 32

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

NRF2↑, 1,   RNS↓, 1,   ROS↓, 1,   SOD1↑, 1,   SOD2↑, 1,  

Cell Death

iNOS↓, 1,  

Transcription & Epigenetics

other↓, 1,  

DNA Damage & Repair

P53↓, 1,  

Cell Cycle & Senescence

E2Fs↑, 1,  

Proliferation, Differentiation & Cell State

IGF-1R↓, 1,  

Migration

AP-1↓, 1,   MMP2↓, 1,  

Angiogenesis & Vasculature

PDGFR-BB↓, 1,  

Barriers & Transport

BBB↑, 1,  

Immune & Inflammatory Signaling

COX2↓, 1,   IL6↓, 1,   IL8↓, 1,   Inflam↓, 1,   JAK↓, 1,   NF-kB↓, 1,   TNF-α↓, 1,  

Drug Metabolism & Resistance

BioAv↓, 2,   BioAv↑, 1,   BioAv↝, 1,   Dose↝, 1,   Half-Life↝, 1,  

Clinical Biomarkers

IL6↓, 1,  

Functional Outcomes

AntiCan↑, 1,   cardioP↑, 1,   hepatoP↓, 1,   neuroP↑, 1,  
Total Targets: 31

Scientific Paper Hit Count for: RNS, reactive nitrogen species
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:0  Cells:%  prod#:%  Target#:276  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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