CD25+ Cancer Research Results

CD25+, IL-2Rα interleukin-2 receptor alpha: Click to Expand ⟱
Source:
Type:
CD25, also known as interleukin-2 receptor alpha (IL-2Rα) chain, is a protein that plays a crucial role in the immune system. Primarily expressed on the surface of activated T cells, regulatory T cells (Tregs), and some types of cancer cells.

CD25+ cells have been found to be associated with various types of tumors.
NA, Not Available: Click to Expand ⟱
none (reserved)
Scientific Papers found: Click to Expand⟱
561- ART/DHA,    Antitumor and immunomodulatory properties of artemether and its ability to reduce CD4+ CD25+ FoxP3+ T reg cells in vivo
- in-vivo, NA, NA
TumCG↓, CD4+↓, CD25+↓, FoxP3+↓, IL4↑,
560- ART/DHA,    Dihydroartemisinin shift the immune response towards Th1, inhibit the tumor growth in vitro and in vivo
- in-vivo, NA, NA
IL4↓, CD4+↓, CD25+↓, FoxP3+↓, Treg lymp↓,
562- ART/DHA,    Artesunate exerts an anti-immunosuppressive effect on cervical cancer by inhibiting PGE2 production and Foxp3 expression
- in-vivo, NA, HeLa
CD4+↓, CD25+↓, FoxP3+↓, Treg lymp↓, PGE2↓, FOXP3↓, COX2↓,

Showing Research Papers: 1 to 3 of 3

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Proliferation, Differentiation & Cell State ⓘ

TumCG↓, 1,  

Migration ⓘ

Treg lymp↓, 2,  

Immune & Inflammatory Signaling ⓘ

CD25+↓, 3,   CD4+↓, 3,   COX2↓, 1,   FOXP3↓, 1,   FoxP3+↓, 3,   IL4↓, 1,   IL4↑, 1,   PGE2↓, 1,  
Total Targets: 10

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: CD25+, IL-2Rα interleukin-2 receptor alpha
3 Artemisinin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:0  Cells:%  prod#:%  Target#:712  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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