BioAv Cancer Research Results

BioAv, bioavailability: Click to Expand ⟱
Source:
Type: measurement
Bioavailability (usually in %) absorbed by the body.
NA, Not Available: Click to Expand ⟱
none (reserved)
Scientific Papers found: Click to Expand⟱
278- ALA,    The Multifaceted Role of Alpha-Lipoic Acid in Cancer Prevention, Occurrence, and Treatment
- Review, NA, NA
ROS↑, NRF2↑, Inflam↓, frataxin↑, *BioAv↓, ChemoSen↑, Hif1a↓, eff↑, FAK↓, ITGB1↓, MMP2↓, MMP9↓, EMT↓, Snail↓, Vim↓, Zeb1↓, P53↑, MGMT↓, Mcl-1↓, Bcl-xL↓, Bcl-2↓, survivin↓, Casp3↑, Casp9↑, BAX↑, p‑Akt↓, GSK‐3β↓, *antiOx↑, *ROS↓, selectivity↑, angioG↓, MMPs↓, NF-kB↓, ITGB3↓, NADPH↓,
1554- Api,    A Review on Flavonoid Apigenin: Dietary Intake, ADME, Antimicrobial Effects, and Interactions with Human Gut Microbiota
- Review, NA, NA
*BioAv↑, *BioAv↑, *BioAv↑, *BioAv↓, *eff↑,
2021- BBR,    Berberine: An Important Emphasis on Its Anticancer Effects through Modulation of Various Cell Signaling Pathways
- Review, NA, NA
*antiOx?, *Inflam↓, Apoptosis↑, TumCCA↑, BAX↑, eff↑, VEGF↓, PI3K↓, Akt↓, mTOR↓, Telomerase↓, β-catenin/ZEB1↓, Wnt↓, EGFR↓, AP-1↓, NF-kB↓, COX2↑, NRF2↓, RadioS↑, STAT3↓, ERK↓, AR↓, ROS↑, eff↑, selectivity↑, selectivity↑, BioAv↓, DNMT1↓, cMyc↓,
5810- CPT,  CPT-11,    Camptothein-Based Anti-Cancer Therapies and Strategies to Improve Their Therapeutic Index
- Review, NA, NA
AntiCan↑, BioAv↓, toxicity⇅, TOP1↓, Apoptosis↑, TumCP↓, other↝, BioAv↑, other↝, eff↑,
3201- EGCG,    Epigallocatechin Gallate (EGCG): Pharmacological Properties, Biological Activities and Therapeutic Potential
- Review, NA, NA
*AntiCan↑, *cardioP↑, *neuroP↑, *BioAv↝, *BioAv↓, *BioAv↓, *Dose↝, *Half-Life↝, *BioAv↑, *BBB↑, *hepatoP↓, *other↓, *Inflam↓, *NF-kB↓, *AP-1↓, *iNOS↓, *COX2↓, *ROS↓, *RNS↓, *IL8↓, *JAK↓, *PDGFR-BB↓, *IGF-1R↓, *MMP2↓, *P53↓, *NRF2↑, *TNF-α↓, *IL6↓, *E2Fs↑, *SOD1↑, *SOD2↑, Casp3↑, Cyt‑c↑, PARP↑, DNMTs↓, Telomerase↓, Hif1a↓, MMPs↓, BAX↑, Bak↑, Bcl-2↓, Bcl-xL↓, P53↑, PTEN↑, TumCP↓, MAPK↓, HGF/c-Met↓, TIMP1↑, HDAC↓, MMP9↓, uPA↓, GlutMet↓, ChemoSen↑, chemoP↑,
2865- HNK,    Liposomal Honokiol induces ROS-mediated apoptosis via regulation of ERK/p38-MAPK signaling and autophagic inhibition in human medulloblastoma
- in-vitro, MB, DAOY - vitro+vivo, NA, NA
BioAv↓, BioAv↓, TumCP↓, selectivity↑, P53↑, P21↑, CDK4↓, cycD1/CCND1↓, mtDam↑, ROS↑, eff↓, Casp3↑, BAX↑, LC3II↑, Beclin-1↑, ATG7↑, p62↑, eff↑, ChemoSen↑, *toxicity↓,
4645- HT,    Hydroxytyrosol: Bioavailability, toxicity, and clinical applications
- Review, NA, NA
*antiOx↑, *Inflam↓, AntiTum↑, *BioAv↓, *Half-Life↓, *BioAv↝, *BioAv↓,
2910- LT,  FA,    Folic acid-modified ROS-responsive nanoparticles encapsulating luteolin for targeted breast cancer treatment
- in-vitro, BC, 4T1 - in-vivo, NA, NA
BioAv↓, BioAv↑, eff↑, tumCV↓, e-H2O2↓, i-H2O2∅,
3260- Lyco,    Lycopene in human health
- Review, NA, NA
*BioAv↝, *BioAv↓, *ROS⇅, *BioAv↝,
2250- MF,  MNPs,    Confronting stem cells with surface-modified magnetic nanoparticles and low-frequency pulsed electromagnetic field
- Review, NA, NA
*Ca+2↑, *Dose↝, *BioAv↓,
1806- NarG,    Naringin: Nanotechnological Strategies for Potential Pharmaceutical Applications
- Review, NA, NA
Inflam↓, antiOx↓, AntiCan↑, BioAv↓, BioAv↓, BioAv↑, INF-γ↓, IL6↓, TNF-α↓, IL10↑, CRP↓,
3247- PBG,    Bioavailability and In Vivo Antioxidant Activity of a Standardized Polyphenol Mixture Extracted from Brown Propolis
- Review, NA, NA
Half-Life↝, BioAv↓, Half-Life↝, BioAv↓,
3248- PBG,    Propolis as a promising functional ingredient: A comprehensive review on extraction, bioactive properties, bioavailability, and industrial applications
- Review, NA, NA
*BioAv↓, *Half-Life↓,
75- QC,  ENZ,    Quercetin targets hnRNPA1 to overcome enzalutamide resistance in prostate cancer cells
- in-vitro, Pca, HEK293 - in-vitro, NA, 22Rv1 - in-vitro, NA, C4-2B
hnRNPA1↓, PSA↓, NKX3.1↓, FKBP5↓, UBE2C↓, AR-FL↓, AR-V7↑, AR↓, eff↑, TumVol↓, BioAv↓,
3335- QC,    Recent advances on the improvement of quercetin bioavailability
- Review, NA, NA
*BioAv↓,
2687- RES,    Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs
- Review, NA, NA - Review, AD, NA
NF-kB↓, P450↓, COX2↓, Hif1a↓, VEGF↓, *SIRT1↑, SIRT1↓, SIRT2↓, ChemoSen⇅, cardioP↑, *memory↑, *angioG↑, *neuroP↑, STAT3↓, CSCs↓, RadioS↑, Nestin↓, Nanog↓, TP53↑, P21↑, CXCR4↓, *BioAv↓, EMT↓, Vim↓, Slug↓, E-cadherin↑, AMPK↑, MDR1↓, DNAdam↑, TOP2↓, PTEN↑, Akt↓, Wnt↓, β-catenin/ZEB1↓, cMyc↓, MMP7↓, MALAT1↓, TCF↓, ALDH↓, CD44↓, Shh↓, IL6↓, VEGF↓, eff↑, HK2↓, ROS↑, MMP↓,
3309- SIL,    Silymarin as a Natural Antioxidant: An Overview of the Current Evidence and Perspectives
- Review, NA, NA
*ROS↓, *IronCh↑, *MMP↑, *NRF2↑, *Inflam↓, *hepatoP↑, *HSPs↑, *Trx↑, *SIRT2↑, *GSH↑, *ROS↑, *NADPH↓, *iNOS↓, *NF-kB↓, *BioAv↓, *Dose↝, *BioAv↑,
3282- SIL,    Role of Silymarin in Cancer Treatment: Facts, Hypotheses, and Questions
- Review, NA, NA
hepatoP↑, AntiCan↑, TumCMig↓, Hif1a↓, selectivity↑, toxicity∅, *antiOx↑, *Inflam↓, TumCCA↑, P21↑, CDK4↓, NF-kB↓, ERK↓, PSA↓, TumCG↓, p27↑, COX2↓, IL1↓, VEGF↓, IGFBP3↑, AR↓, STAT3↓, Telomerase↓, Cyt‑c↑, Casp↑, eff↝, HDAC↓, HATs↑, Zeb1↓, E-cadherin↑, miR-203↑, NHE1↓, MMP2↓, MMP9↓, PGE2↓, Vim↓, Wnt↓, angioG↓, VEGF↓, *TIMP1↓, EMT↓, TGF-β↓, CD44↓, EGFR↓, PDGF↓, *IL8↓, SREBP1↓, MMP↓, ATP↓, uPA↓, PD-L1↓, NOTCH↓, *SIRT1↑, SIRT1↓, CA↓, Ca+2↑, chemoP↑, cardioP↑, Dose↝, Half-Life↝, BioAv↓, BioAv↓, BioAv↓, toxicity↝, Half-Life↓, ROS↓, FAK↓,
1343- SK,    Simple ROS-responsive micelles loaded Shikonin for efficient ovarian cancer targeting therapy by disrupting intracellular redox homeostasis
- in-vitro, Ovarian, A2780S - in-vivo, NA, A2780S
*BioAv↓, ROS↑, GSH↓, TumCG↓,
5328- TFdiG,    Study on mechanism of low bioavailability of black tea theaflavins by using Caco-2 cell monolayer
- in-vitro, NA, Caco-2
BioAv↓, P-gp↑, MRP1↑, ROS↑, *BioAv↓,
596- VitC,    High-Dose Vitamin C in Advanced-Stage Cancer Patients
- Review, NA, NA
ChemoSideEff↓, ROS↑, H2O2↑, Fenton↑, Hif1a↝, Dose↑, BioAv↓, Dose↝, Half-Life↝, IL1β↓, IL2↓, IL8↓, TNF-α↓,

Showing Research Papers: 1 to 21 of 21

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 21

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↓, 1,   Fenton↑, 1,   frataxin↑, 1,   GSH↓, 1,   H2O2↑, 1,   e-H2O2↓, 1,   i-H2O2∅, 1,   NRF2↓, 1,   NRF2↑, 1,   ROS↓, 1,   ROS↑, 7,  

Mitochondria & Bioenergetics ⓘ

ATP↓, 1,   MMP↓, 2,   mtDam↑, 1,  

Core Metabolism/Glycolysis ⓘ

AMPK↑, 1,   ATG7↑, 1,   cMyc↓, 2,   GlutMet↓, 1,   HK2↓, 1,   NADPH↓, 1,   SIRT1↓, 2,   SIRT2↓, 1,   SREBP1↓, 1,  

Cell Death ⓘ

Akt↓, 2,   p‑Akt↓, 1,   Apoptosis↑, 2,   Bak↑, 1,   BAX↑, 4,   Bcl-2↓, 2,   Bcl-xL↓, 2,   Casp↑, 1,   Casp3↑, 3,   Casp9↑, 1,   Cyt‑c↑, 2,   HGF/c-Met↓, 1,   MAPK↓, 1,   Mcl-1↓, 1,   p27↑, 1,   survivin↓, 1,   Telomerase↓, 3,  

Transcription & Epigenetics ⓘ

HATs↑, 1,   other↝, 2,   tumCV↓, 1,  

Autophagy & Lysosomes ⓘ

Beclin-1↑, 1,   LC3II↑, 1,   p62↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 1,   DNMT1↓, 1,   DNMTs↓, 1,   MGMT↓, 1,   NKX3.1↓, 1,   P53↑, 3,   PARP↑, 1,   TP53↑, 1,  

Cell Cycle & Senescence ⓘ

CDK4↓, 2,   cycD1/CCND1↓, 1,   P21↑, 3,   TumCCA↑, 2,  

Proliferation, Differentiation & Cell State ⓘ

ALDH↓, 1,   AR-FL↓, 1,   AR-V7↑, 1,   CD44↓, 2,   CSCs↓, 1,   EMT↓, 3,   ERK↓, 2,   GSK‐3β↓, 1,   HDAC↓, 2,   IGFBP3↑, 1,   mTOR↓, 1,   Nanog↓, 1,   Nestin↓, 1,   NOTCH↓, 1,   PI3K↓, 1,   PTEN↑, 2,   Shh↓, 1,   STAT3↓, 3,   TCF↓, 1,   TOP1↓, 1,   TOP2↓, 1,   TumCG↓, 2,   Wnt↓, 3,  

Migration ⓘ

AP-1↓, 1,   CA↓, 1,   Ca+2↑, 1,   E-cadherin↑, 2,   FAK↓, 2,   hnRNPA1↓, 1,   ITGB1↓, 1,   ITGB3↓, 1,   MALAT1↓, 1,   miR-203↑, 1,   MMP2↓, 2,   MMP7↓, 1,   MMP9↓, 3,   MMPs↓, 2,   PDGF↓, 1,   Slug↓, 1,   Snail↓, 1,   TGF-β↓, 1,   TIMP1↑, 1,   TumCMig↓, 1,   TumCP↓, 3,   uPA↓, 2,   Vim↓, 3,   Zeb1↓, 2,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature ⓘ

angioG↓, 2,   EGFR↓, 2,   Hif1a↓, 4,   Hif1a↝, 1,   VEGF↓, 5,  

Barriers & Transport ⓘ

NHE1↓, 1,   P-gp↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 2,   COX2↑, 1,   CRP↓, 1,   CXCR4↓, 1,   IL1↓, 1,   IL10↑, 1,   IL1β↓, 1,   IL2↓, 1,   IL6↓, 2,   IL8↓, 1,   INF-γ↓, 1,   Inflam↓, 2,   NF-kB↓, 4,   PD-L1↓, 1,   PGE2↓, 1,   PSA↓, 2,   TNF-α↓, 2,  

Hormonal & Nuclear Receptors ⓘ

AR↓, 3,   FKBP5↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 15,   BioAv↑, 3,   ChemoSen↑, 3,   ChemoSen⇅, 1,   Dose↑, 1,   Dose↝, 2,   eff↓, 1,   eff↑, 8,   eff↝, 1,   Half-Life↓, 1,   Half-Life↝, 4,   MDR1↓, 1,   MRP1↑, 1,   P450↓, 1,   RadioS↑, 2,   selectivity↑, 5,  

Clinical Biomarkers ⓘ

AR↓, 3,   CRP↓, 1,   EGFR↓, 2,   IL6↓, 2,   PD-L1↓, 1,   PSA↓, 2,   TP53↑, 1,  

Functional Outcomes ⓘ

AntiCan↑, 3,   AntiTum↑, 1,   cardioP↑, 2,   chemoP↑, 2,   ChemoSideEff↓, 1,   hepatoP↑, 1,   toxicity⇅, 1,   toxicity↝, 1,   toxicity∅, 1,   TumVol↓, 1,   UBE2C↓, 1,  
Total Targets: 166

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx?, 1,   antiOx↑, 3,   GSH↑, 1,   NRF2↑, 2,   RNS↓, 1,   ROS↓, 3,   ROS↑, 1,   ROS⇅, 1,   SOD1↑, 1,   SOD2↑, 1,   Trx↑, 1,  

Metal & Cofactor Biology ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics ⓘ

MMP↑, 1,  

Core Metabolism/Glycolysis ⓘ

NADPH↓, 1,   SIRT1↑, 2,   SIRT2↑, 1,  

Cell Death ⓘ

iNOS↓, 2,  

Transcription & Epigenetics ⓘ

other↓, 1,  

Protein Folding & ER Stress ⓘ

HSPs↑, 1,  

DNA Damage & Repair ⓘ

P53↓, 1,  

Cell Cycle & Senescence ⓘ

E2Fs↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

IGF-1R↓, 1,  

Migration ⓘ

AP-1↓, 1,   Ca+2↑, 1,   MMP2↓, 1,   TIMP1↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↑, 1,   PDGFR-BB↓, 1,  

Barriers & Transport ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   IL6↓, 1,   IL8↓, 2,   Inflam↓, 5,   JAK↓, 1,   NF-kB↓, 2,   TNF-α↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 14,   BioAv↑, 5,   BioAv↝, 4,   Dose↝, 3,   eff↑, 1,   Half-Life↓, 2,   Half-Life↝, 1,  

Clinical Biomarkers ⓘ

IL6↓, 1,  

Functional Outcomes ⓘ

AntiCan↑, 1,   cardioP↑, 1,   hepatoP↓, 1,   hepatoP↑, 1,   memory↑, 1,   neuroP↑, 2,   toxicity↓, 1,  
Total Targets: 51

Scientific Paper Hit Count for: BioAv, bioavailability
2 Propolis -bee glue
2 Quercetin
2 Silymarin (Milk Thistle) silibinin
1 Alpha-Lipoic-Acid
1 Apigenin (mainly Parsley)
1 Berberine
1 Camptothecin
1 irinotecan
1 EGCG (Epigallocatechin Gallate)
1 Honokiol
1 HydroxyTyrosol
1 Luteolin
1 Folic Acid, Vit B9
1 Lycopene
1 Magnetic Fields
1 magnetic nanoparticles
1 Naringin
1 enzalutamide
1 Resveratrol
1 Shikonin
1 Aflavin-3,3′-digallate
1 Vitamin C (Ascorbic Acid)
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:0  Cells:%  prod#:%  Target#:792  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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