AntiAg Cancer Research Results

AntiAg, Antiplatelet aggregation: Click to Expand ⟱
Source:
Type:
Antiplatelet aggregation refers to the process by which platelets clump together to form a blood clot.
The plethora of evidence indicates that among multiple hemostasis components, platelets play major roles in cancer progression by providing surface and granular contents for several interactions as well as behaving like immune cells.On the other hand, there are suggestions that antiplatelet treatment may promote solid tumor development in a phenomenon described as “cancers follow bleeding.” The controversies around antiplatelet agents justify insight into the subject to establish what, if any, role platelet-directed therapy has in the continuum of anticancer management.
The interplay between antiplatelet aggregation and cancer is an area of active research, with potential implications for therapeutic strategies. Antiplatelet agents, such as aspirin, are being investigated for their role in cancer prevention and treatment, particularly in reducing metastasis and improving patient outcomes.
NA, Not Available: Click to Expand ⟱
none (reserved)
Scientific Papers found: Click to Expand⟱
4574- AgNPs,    Advances in nano silver-based biomaterials and their biomedical applications
- Review, NA, NA
*Wound Healing↑, *AntiThr↑, *AntiAg↑, eff↑,
4580- AgNPs,    Biogenic Synthesis of Antibacterial, Hemocompatible, and Antiplatelets Lysozyme Functionalized Silver Nanoparticles through the One-Step Process for Therapeutic Applications
- in-vitro, NA, NA
*AntiAg↑,
4576- AgNPs,    Nanosilver, Next-Generation Antithrombotic Agent
- Study, NA, NA
*AntiAg↑, *Bacteria↓,
2461- ASA,    Aspirin and platelets: the antiplatelet action of aspirin and its role in thrombosis treatment and prophylaxis
- Review, NA, NA
AntiAg↑, COX1↓, eff↑,
5412- ASA,    Clinical Pharmacology of Aspirin
- Review, NA, NA
*COX1↓, *COX2↓, *cardioP↑, *BioAv↑, *BioAv↝, *Half-Life↓, Risk↓, *other↑, *AntiAg↑,
4340- BBR,    Agonist-dependent differential effects of berberine in human platelet aggregation
- Human, NA, NA
*AntiAg↑, *other?,
4342- CA,    Antiplatelet effects of caffeic acid due to Ca(2＋) mobilizationinhibition via cAMP-dependent inositol-1, 4, 5-trisphosphate receptor phosphorylation
- in-vitro, NA, NA
*AntiAg↑, *TXA2↓, *COX1↓,
3890- Cin,    The Therapeutic Roles of Cinnamaldehyde against Cardiovascular Diseases
- Review, NA, NA
*cardioP↑, *Inflam↓, *ROS↓, *lipid-P↓, *AntiAg↑, *angioG↑, *GutMicro↑, *ER Stress↓,
4337- CUR,    Inhibitory effect of curcumin, a food spice from turmeric, on platelet-activating factor- and arachidonic acid-mediated platelet aggregation through inhibition of thromboxane formation and Ca2+ signaling
- in-vitro, NA, NA
*AntiAg↑, *TXA2↓,
4989- Dipy,    Dipyridamole
- Review, NA, NA
AntiAg↑,
4341- EA,    Novel Bioactivity of Ellagic Acid in Inhibiting Human Platelet Activation
- in-vitro, NA, NA
*AntiAg↑, *AntiAg↑,
2562- EGCG,    Green Tea Epigallocatechin 3-Gallate Reduced Platelet Aggregation and Improved Anticoagulant Proteins in Patients with Transfusion-Dependent β-Thalassemia: A Randomized Placebo-Controlled Clinical Trial
- Trial, NA, NA
AntiAg↑, other↝,
2563- EGCG,    Cardioprotective effect of epigallocatechin gallate in myocardial ischemia/reperfusion injury and myocardial infarction: a meta-analysis in preclinical animal studies
- Review, NA, NA
cardioP↑, ROS↑, AntiAg↑, eff↑, COX1↓,
4343- H2,    Inhibitory effects of hydrogen on in vitro platelet activation and in vivo prevention of thrombosis formation
- vitro+vivo, NA, NA
*antiOx↑, *AntiAg↑, *NO↑, *ERK↑,
4344- H2,    Hydrogen May Inhibit Collagen-Induced Platelet Aggregation: An ex vivo and in vivo Study
- in-vivo, NA, NA - ex-vivo, NA, NA
*AntiAg↑,
4347- H2,    Hydrogen may inhibit collagen-induced platelet aggregation: an ex vivo and in vivo study
- ex-vivo, NA, NA
*AntiAg↑,
4346- H2,    Medical Application of Hydrogen in Hematological Diseases
- Review, NA, NA
*AntiAg↑, *TNF-α↓, *IL6↓, *IFN-γ↓, *NF-kB↓,
4345- H2,    The Benefit of Hydrogen Gas as an Adjunctive Therapy for Chronic Obstructive Pulmonary Disease
- Human, NA, NA
*Inflam↓, *antiOx↑, *ROS↓, *NLRP3↑, *NF-kB↓, *SOD↑, *Catalase↑, *AntiAg↑,
4339- LT,    Luteolin inhibits GPVI-mediated platelet activation, oxidative stress, and thrombosis
- in-vivo, NA, NA
*AntiAg↑, *ROS↓,
4338- LT,    Luteolin: a natural product with multiple mechanisms for atherosclerosis
- Review, NA, NA
*Inflam↓, *ROS↓, *PDGF↓, *lipid-P↓, *AMPK↑, *SIRT1↑, *AntiAg↑,
1807- NarG,    A Systematic Review of the Preventive and Therapeutic Effects of Naringin Against Human Malignancies
- Review, NA, NA
AntiTum↑, TumCP↓, tumCV↓, TumCCA↑, Mcl-1↓, RAS↓, e-Raf↓, VEGF↓, AntiAg↑, MMP2↓, MMP9↓, TIMP2↑, TIMP1↑, p38↓, Wnt↓, β-catenin/ZEB1↑, Casp↑, P53↑, BAX↑, COX2↓, GLO-I↓, CYP1A1↑, lipid-P↓, p‑Akt↓, p‑mTOR↓, VCAM-1↓, P-gp↓, survivin↓, Bcl-2↓, ROS↑, ROS↑, MAPK↑, STAT3↓, chemoP↑,
3348- QC,    Quercetin and iron metabolism: What we know and what we need to know
- Review, NA, NA
*IronCh↑, *ROS↓, *AntiAg↑, *Fenton↓, *lipid-P↓, *hepatoP↑, *RenoP↑, HIF-1↑, ROS↑,
2565- RES,    https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2141.2007.06788.x
- in-vitro, NA, NA - in-vivo, NA, NA
AntiAg↑, TXA2↑, PKCδ↑, Dose↝,
2564- RES,    Effect of resveratrol on platelet aggregation by fibrinogen protection
- in-vitro, NA, NA
AntiAg↑, antiOx↓, COX2↓,
4575- RT,  AgNPs,    Rutin-Loaded Silver Nanoparticles With Antithrombotic Function
- in-vivo, NA, NA
*AntiThr↑, *AntiAg↑, *antiOx↑, *Inflam↓,

Showing Research Papers: 1 to 25 of 25

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 25

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↓, 1,   CYP1A1↑, 1,   lipid-P↓, 1,   ROS↑, 4,  

Mitochondria & Bioenergetics ⓘ

e-Raf↓, 1,  

Core Metabolism/Glycolysis ⓘ

GLO-I↓, 1,  

Cell Death ⓘ

p‑Akt↓, 1,   BAX↑, 1,   Bcl-2↓, 1,   Casp↑, 1,   MAPK↑, 1,   Mcl-1↓, 1,   p38↓, 1,   survivin↓, 1,  

Transcription & Epigenetics ⓘ

other↝, 1,   tumCV↓, 1,  

DNA Damage & Repair ⓘ

P53↑, 1,  

Cell Cycle & Senescence ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

p‑mTOR↓, 1,   RAS↓, 1,   STAT3↓, 1,   Wnt↓, 1,  

Migration ⓘ

AntiAg↑, 7,   MMP2↓, 1,   MMP9↓, 1,   PKCδ↑, 1,   TIMP1↑, 1,   TIMP2↑, 1,   TumCP↓, 1,   VCAM-1↓, 1,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature ⓘ

HIF-1↑, 1,   TXA2↑, 1,   VEGF↓, 1,  

Barriers & Transport ⓘ

P-gp↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX1↓, 2,   COX2↓, 2,  

Drug Metabolism & Resistance ⓘ

Dose↝, 1,   eff↑, 3,  

Functional Outcomes ⓘ

AntiTum↑, 1,   cardioP↑, 1,   chemoP↑, 1,   Risk↓, 1,  
Total Targets: 43

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 3,   Catalase↑, 1,   Fenton↓, 1,   lipid-P↓, 3,   ROS↓, 5,   SOD↑, 1,  

Metal & Cofactor Biology ⓘ

IronCh↑, 1,  

Core Metabolism/Glycolysis ⓘ

AMPK↑, 1,   SIRT1↑, 1,  

Transcription & Epigenetics ⓘ

AntiThr↑, 2,   other?, 1,   other↑, 1,  

Protein Folding & ER Stress ⓘ

ER Stress↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

ERK↑, 1,  

Migration ⓘ

AntiAg↑, 19,   PDGF↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↑, 1,   NO↑, 1,   TXA2↓, 2,  

Immune & Inflammatory Signaling ⓘ

COX1↓, 2,   COX2↓, 1,   IFN-γ↓, 1,   IL6↓, 1,   Inflam↓, 4,   NF-kB↓, 2,   TNF-α↓, 1,  

Protein Aggregation ⓘ

NLRP3↑, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 1,   BioAv↝, 1,   Half-Life↓, 1,  

Clinical Biomarkers ⓘ

GutMicro↑, 1,   IL6↓, 1,  

Functional Outcomes ⓘ

cardioP↑, 2,   hepatoP↑, 1,   RenoP↑, 1,   Wound Healing↑, 1,  

Infection & Microbiome ⓘ

Bacteria↓, 1,  
Total Targets: 37

Scientific Paper Hit Count for: AntiAg, Antiplatelet aggregation
5 Hydrogen Gas
4 Silver-NanoParticles
2 Aspirin -acetylsalicylic acid
2 EGCG (Epigallocatechin Gallate)
2 Luteolin
2 Resveratrol
1 Berberine
1 Caffeic acid
1 Cinnamon
1 Curcumin
1 Dipyridamole
1 Ellagic acid
1 Naringin
1 Quercetin
1 Rutin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:0  Cells:%  prod#:%  Target#:10  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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