radioP Cancer Research Results
radioP, RadioProtective: Click to Expand ⟱
| Source: |
| Type: |
Protect against the damaging effects of radiation therapy.
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NA, Not Available: Click to Expand ⟱
Scientific Papers found: Click to Expand⟱
radioP↑, selectivity↑,
Apoptosis↑, selectivity↑, eff↓, ROS↑, lipid-P↑, P53↑, radioP↑, chemoP↑,
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in-vitro, |
Nor, |
HUVECs |
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in-vivo, |
NA, |
NA |
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AntiTum↑, OS↑, QoL↑, TumVol↓, radioP↑, Dose↑, Dose↝, eff↑,
Remission↑, OS↑, neuroP↑, VEGF↓, KISS1↑, TumCP↓, ChemoSideEff↓, radioP↑, Dose∅, *ROS↓, DNArepair↑, ROS↑,
*antiOx↑, *RenoP↑, *hepatoP↑, *radioP↑, *eff↑, *toxicity↓, *ROS↓, *lipid-P↓, *DNAdam↓, *Catalase↑, *SOD↑, *GPx↑, *GSR↑, *GSTs↑, *AST↓, *ALAT↓, *ALP↓, *Bil↓,
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in-vitro, |
Pca, |
LNCaP |
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- |
in-vitro, |
Pca, |
DU145 |
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in-vitro, |
Nor, |
PrEC |
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- |
in-vivo, |
NA, |
NA |
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ROS↑, NADPH↑, RadioS↑, radioP↑, Trx↓, *ox-Keap1↑, ox-Keap1↓, rd-Keap1↑, *NRF2↑, NRF2∅, NF-kB↓,
ROS⇅, *antiOx↑, *SOD↑, *MPO↑, *neuroP↑, *chemoP↑, *radioP↑, NF-kB↓, IAP1↓, IAP2↓, XIAP↓, Bcl-xL↓, survivin↓, COX2↓, MMP9↓, VEGF↓, ROS↑, P21↑, HDAC↓, GSH↓, GADD45A↑, AIF↑, STAT3↓,
*antiOx↑, *ROS↓, *GSTs↑, *GSR↑, *GSH↑, *RenoP↑, *IL1β↓, *TNF-α↓, *MMP13↓, *COX2↓, *PGE2↓, *radioP↑, Twist↓, EMT↓, NF-kB↓, p‑PI3K↓, p‑Akt↓, p‑GSK‐3β↓, DNMT1↓, HDAC↓,
*radioP↑, *ROS↓,
radioP↑,
Showing Research Papers: 1 to 10 of 10
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 10
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
GSH↓, 1, ox-Keap1↓, 1, rd-Keap1↑, 1, lipid-P↑, 1, NRF2∅, 1, ROS↑, 4, ROS⇅, 1, Trx↓, 1,
Mitochondria & Bioenergetics ⓘ
AIF↑, 1, XIAP↓, 1,
Core Metabolism/Glycolysis ⓘ
NADPH↑, 1,
Cell Death ⓘ
p‑Akt↓, 1, Apoptosis↑, 1, Bcl-xL↓, 1, IAP1↓, 1, IAP2↓, 1, survivin↓, 1,
Transcription & Epigenetics ⓘ
KISS1↑, 1,
DNA Damage & Repair ⓘ
DNArepair↑, 1, DNMT1↓, 1, GADD45A↑, 1, P53↑, 1,
Cell Cycle & Senescence ⓘ
P21↑, 1,
Proliferation, Differentiation & Cell State ⓘ
EMT↓, 1, p‑GSK‐3β↓, 1, HDAC↓, 2, p‑PI3K↓, 1, STAT3↓, 1,
Migration ⓘ
MMP9↓, 1, TumCP↓, 1, Twist↓, 1,
Angiogenesis & Vasculature ⓘ
VEGF↓, 2,
Immune & Inflammatory Signaling ⓘ
COX2↓, 1, NF-kB↓, 3,
Drug Metabolism & Resistance ⓘ
Dose↑, 1, Dose↝, 1, Dose∅, 1, eff↓, 1, eff↑, 1, RadioS↑, 1, selectivity↑, 2,
Functional Outcomes ⓘ
AntiTum↑, 1, chemoP↑, 1, ChemoSideEff↓, 1, neuroP↑, 1, OS↑, 2, QoL↑, 1, radioP↑, 6, Remission↑, 1, TumVol↓, 1,
Total Targets: 50
Pathway results for Effect on Normal Cells:
Redox & Oxidative Stress ⓘ
antiOx↑, 3, Bil↓, 1, Catalase↑, 1, GPx↑, 1, GSH↑, 1, GSR↑, 2, GSTs↑, 2, ox-Keap1↑, 1, lipid-P↓, 1, MPO↑, 1, NRF2↑, 1, ROS↓, 4, SOD↑, 2,
Core Metabolism/Glycolysis ⓘ
ALAT↓, 1,
DNA Damage & Repair ⓘ
DNAdam↓, 1,
Migration ⓘ
MMP13↓, 1,
Immune & Inflammatory Signaling ⓘ
COX2↓, 1, IL1β↓, 1, PGE2↓, 1, TNF-α↓, 1,
Drug Metabolism & Resistance ⓘ
eff↑, 1,
Clinical Biomarkers ⓘ
ALAT↓, 1, ALP↓, 1, AST↓, 1, Bil↓, 1,
Functional Outcomes ⓘ
chemoP↑, 1, hepatoP↑, 1, neuroP↑, 1, radioP↑, 4, RenoP↑, 2, toxicity↓, 1,
Total Targets: 31
Scientific Paper Hit Count for: radioP, RadioProtective
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:0 Cells:% prod#:% Target#:1185 State#:% Dir#:2
wNotes=0 sortOrder:rid,rpid
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