cardioP Cancer Research Results

cardioP, cardioProtective: Click to Expand ⟱
Source:
Type:
CardioProtective


NA, Not Available: Click to Expand ⟱
none (reserved)
Scientific Papers found: Click to Expand⟱
3438- ALA,    The Potent Antioxidant Alpha Lipoic Acid
- Review, NA, NA - Review, AD, NA
*antiOx↑, *cardioP↑, *cognitive↑, *AntiAge↑, *Inflam↓, *AntiCan↑, *neuroP↑, *IronCh↑, *ROS↑, *Weight↓, *Ach↑, *ROS↓, *GSH↑, *lipid-P↓, *memory↑, *NRF2↑, *ChAT↑, *GlucoseCon↑, *Acetyl-CoA↑,
2636- Api,    Apigenin unveiled: an encyclopedic review of its preclinical and clinical insights
- Review, NA, NA
*AntiCan↑, *cardioP↑, *neuroP↑, *Inflam↓, *antiOx↑, *hepatoP↑, ChemoSen↑,
5412- ASA,    Clinical Pharmacology of Aspirin
- Review, NA, NA
*COX1↓, *COX2↓, *cardioP↑, *BioAv↑, *BioAv↝, *Half-Life↓, Risk↓, *other↑, *AntiAg↑,
3672- Ash,    Critical review of the Withania somnifera (L.) Dunal: ethnobotany, pharmacological efficacy, and commercialization significance in Africa
- Review, NA, NA
*cardioP↑, *antiOx↑, *ROS↓, *neuroP↑, *Inflam↓, *Apoptosis↓,
3502- Bor,    Plasma boron concentrations in the general population: a cross-sectional analysis of cardio-metabolic and dietary correlates
- Review, NA, NA
*Half-Life↑, *VitD↑, *cardioP↑, *RenoP↓,
3890- Cin,    The Therapeutic Roles of Cinnamaldehyde against Cardiovascular Diseases
- Review, NA, NA
*cardioP↑, *Inflam↓, *ROS↓, *lipid-P↓, *AntiAg↑, *angioG↑, *GutMicro↑, *ER Stress↓,
3201- EGCG,    Epigallocatechin Gallate (EGCG): Pharmacological Properties, Biological Activities and Therapeutic Potential
- Review, NA, NA
*AntiCan↑, *cardioP↑, *neuroP↑, *BioAv↝, *BioAv↓, *BioAv↓, *Dose↝, *Half-Life↝, *BioAv↑, *BBB↑, *hepatoP↓, *other↓, *Inflam↓, *NF-kB↓, *AP-1↓, *iNOS↓, *COX2↓, *ROS↓, *RNS↓, *IL8↓, *JAK↓, *PDGFR-BB↓, *IGF-1R↓, *MMP2↓, *P53↓, *NRF2↑, *TNF-α↓, *IL6↓, *E2Fs↑, *SOD1↑, *SOD2↑, Casp3↑, Cyt‑c↑, PARP↑, DNMTs↓, Telomerase↓, Hif1a↓, MMPs↓, BAX↑, Bak↑, Bcl-2↓, Bcl-xL↓, P53↑, PTEN↑, TumCP↓, MAPK↓, HGF/c-Met↓, TIMP1↑, HDAC↓, MMP9↓, uPA↓, GlutMet↓, ChemoSen↑, chemoP↑,
3211- EGCG,    Antioxidation Function of EGCG by Activating Nrf2/HO-1 Pathway in Mice with Coronary Heart Disease
- in-vivo, NA, NA
*cardioP↑, *VEGF↓, *MMP2↓, *SOD↑, *ROS↓, *HO-1↑, *NQO1↑, *NRF2↑,
2563- EGCG,    Cardioprotective effect of epigallocatechin gallate in myocardial ischemia/reperfusion injury and myocardial infarction: a meta-analysis in preclinical animal studies
- Review, NA, NA
cardioP↑, ROS↑, AntiAg↑, eff↑, COX1↓,
2525- H2,    Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis
- in-vivo, NA, NA
OS↓, cardioP↑, *AST↓, ALAT↓, *ROS↓, *MDA↓, *hepatoP↑, *Inflam↓, chemoP↑,
3482- MF,    Pulsed Electromagnetic Fields Increase Angiogenesis and Improve Cardiac Function After Myocardial Ischemia in Mice
- in-vitro, NA, NA
*cardioP↑, *VEGF↑, *VEGFR2↑, *Hif1a↑, *FGF↑, *ITGB1↑, *angioG↑,
1798- NarG,    Naringenin: A potential flavonoid phytochemical for cancer therapy
- Review, NA, NA
*Inflam↓, *antiOx↓, neuroP↑, hepatoP↑, AntiCan↑, Apoptosis↑, TumCCA↑, angioG↓, ROS↝, SOD↑, TGF-β↓, Treg lymp↓, IL1β↓, *BioAv↝, ChemoSen↑, cardioP↑,
3252- PBG,    Propolis Extract and Its Bioactive Compounds—From Traditional to Modern Extraction Technologies
- Review, NA, NA
*Inflam↓, *TNF-α↓, *NF-kB↓, *MAPK↓, *ERK↓, *antiOx↑, *NRF2↑, *cardioP↑, *Glycolysis↑, *Ca+2↓, *HO-1↑, *NRF2↑, *neuroP↑,
2303- QC,  doxoR,    Quercetin greatly improved therapeutic index of doxorubicin against 4T1 breast cancer by its opposing effects on HIF-1α in tumor and normal cells
- in-vitro, BC, 4T1 - in-vivo, NA, NA
cardioP↑, hepatoP↑, TumCG↓, OS↑, ChemoSen↑, chemoP↑, Hif1a↓, *Hif1a↑, selectivity↑, TumVol↓, OS↑,
2687- RES,    Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs
- Review, NA, NA - Review, AD, NA
NF-kB↓, P450↓, COX2↓, Hif1a↓, VEGF↓, *SIRT1↑, SIRT1↓, SIRT2↓, ChemoSen⇅, cardioP↑, *memory↑, *angioG↑, *neuroP↑, STAT3↓, CSCs↓, RadioS↑, Nestin↓, Nanog↓, TP53↑, P21↑, CXCR4↓, *BioAv↓, EMT↓, Vim↓, Slug↓, E-cadherin↑, AMPK↑, MDR1↓, DNAdam↑, TOP2↓, PTEN↑, Akt↓, Wnt↓, β-catenin/ZEB1↓, cMyc↓, MMP7↓, MALAT1↓, TCF↓, ALDH↓, CD44↓, Shh↓, IL6↓, VEGF↓, eff↑, HK2↓, ROS↑, MMP↓,
3282- SIL,    Role of Silymarin in Cancer Treatment: Facts, Hypotheses, and Questions
- Review, NA, NA
hepatoP↑, AntiCan↑, TumCMig↓, Hif1a↓, selectivity↑, toxicity∅, *antiOx↑, *Inflam↓, TumCCA↑, P21↑, CDK4↓, NF-kB↓, ERK↓, PSA↓, TumCG↓, p27↑, COX2↓, IL1↓, VEGF↓, IGFBP3↑, AR↓, STAT3↓, Telomerase↓, Cyt‑c↑, Casp↑, eff↝, HDAC↓, HATs↑, Zeb1↓, E-cadherin↑, miR-203↑, NHE1↓, MMP2↓, MMP9↓, PGE2↓, Vim↓, Wnt↓, angioG↓, VEGF↓, *TIMP1↓, EMT↓, TGF-β↓, CD44↓, EGFR↓, PDGF↓, *IL8↓, SREBP1↓, MMP↓, ATP↓, uPA↓, PD-L1↓, NOTCH↓, *SIRT1↑, SIRT1↓, CA↓, Ca+2↑, chemoP↑, cardioP↑, Dose↝, Half-Life↝, BioAv↓, BioAv↓, BioAv↓, toxicity↝, Half-Life↓, ROS↓, FAK↓,
3951- Taur,    Taurine Supplementation Alleviates Blood Pressure via Gut–Brain Communication in Spontaneously Hypertensive Rats
- in-vivo, NA, NA
*BP↓, *Inflam↓, *ROS↓, *cardioP↑, *GutMicro↑, *BBB↑,
3405- TQ,  doxoR,    Protective effect of thymoquinone against doxorubicin-induced cardiotoxicity and the underlying mechanism
- vitro+vivo, NA, NA
*cardioP↑, *NRF2↑, *HO-1↑, *ROS↓, *NQO1↑, *COX2↓, *NOX4↓, *GPx4↑, *FTH1↑, *p‑mTOR↓, *TGF-β↓,
4031- VitB3,    Nicotinamide Riboside-The Current State of Research and Therapeutic Uses
- Review, NA, NA
*cardioP↑, *neuroP↑, *NAD↑, *SIRT1↑, *NADPH↑, *ROS↓, *IL2↓, *IL5↓, *IL6↓, *TNF-α↓, *Inflam↓, *BioAv↝, *BioAv↑,

Showing Research Papers: 1 to 19 of 19

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 19

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

ROS↓, 1,   ROS↑, 2,   ROS↝, 1,   SOD↑, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↓, 1,   MMP↓, 2,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 1,   AMPK↑, 1,   cMyc↓, 1,   GlutMet↓, 1,   HK2↓, 1,   SIRT1↓, 2,   SIRT2↓, 1,   SREBP1↓, 1,  

Cell Death ⓘ

Akt↓, 1,   Apoptosis↑, 1,   Bak↑, 1,   BAX↑, 1,   Bcl-2↓, 1,   Bcl-xL↓, 1,   Casp↑, 1,   Casp3↑, 1,   Cyt‑c↑, 2,   HGF/c-Met↓, 1,   MAPK↓, 1,   p27↑, 1,   Telomerase↓, 2,  

Transcription & Epigenetics ⓘ

HATs↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 1,   DNMTs↓, 1,   P53↑, 1,   PARP↑, 1,   TP53↑, 1,  

Cell Cycle & Senescence ⓘ

CDK4↓, 1,   P21↑, 2,   TumCCA↑, 2,  

Proliferation, Differentiation & Cell State ⓘ

ALDH↓, 1,   CD44↓, 2,   CSCs↓, 1,   EMT↓, 2,   ERK↓, 1,   HDAC↓, 2,   IGFBP3↑, 1,   Nanog↓, 1,   Nestin↓, 1,   NOTCH↓, 1,   PTEN↑, 2,   Shh↓, 1,   STAT3↓, 2,   TCF↓, 1,   TOP2↓, 1,   TumCG↓, 2,   Wnt↓, 2,  

Migration ⓘ

AntiAg↑, 1,   CA↓, 1,   Ca+2↑, 1,   E-cadherin↑, 2,   FAK↓, 1,   MALAT1↓, 1,   miR-203↑, 1,   MMP2↓, 1,   MMP7↓, 1,   MMP9↓, 2,   MMPs↓, 1,   PDGF↓, 1,   Slug↓, 1,   TGF-β↓, 2,   TIMP1↑, 1,   Treg lymp↓, 1,   TumCMig↓, 1,   TumCP↓, 1,   uPA↓, 2,   Vim↓, 2,   Zeb1↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 2,   EGFR↓, 1,   Hif1a↓, 4,   VEGF↓, 4,  

Barriers & Transport ⓘ

NHE1↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX1↓, 1,   COX2↓, 2,   CXCR4↓, 1,   IL1↓, 1,   IL1β↓, 1,   IL6↓, 1,   NF-kB↓, 2,   PD-L1↓, 1,   PGE2↓, 1,   PSA↓, 1,  

Hormonal & Nuclear Receptors ⓘ

AR↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 3,   ChemoSen↑, 4,   ChemoSen⇅, 1,   Dose↝, 1,   eff↑, 2,   eff↝, 1,   Half-Life↓, 1,   Half-Life↝, 1,   MDR1↓, 1,   P450↓, 1,   RadioS↑, 1,   selectivity↑, 2,  

Clinical Biomarkers ⓘ

ALAT↓, 1,   AR↓, 1,   EGFR↓, 1,   IL6↓, 1,   PD-L1↓, 1,   PSA↓, 1,   TP53↑, 1,  

Functional Outcomes ⓘ

AntiCan↑, 2,   cardioP↑, 6,   chemoP↑, 4,   hepatoP↑, 3,   neuroP↑, 1,   OS↓, 1,   OS↑, 2,   Risk↓, 1,   toxicity↝, 1,   toxicity∅, 1,   TumVol↓, 1,  
Total Targets: 121

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↓, 1,   antiOx↑, 5,   GPx4↑, 1,   GSH↑, 1,   HO-1↑, 3,   lipid-P↓, 2,   MDA↓, 1,   NOX4↓, 1,   NQO1↑, 2,   NRF2↑, 6,   RNS↓, 1,   ROS↓, 9,   ROS↑, 1,   SOD↑, 1,   SOD1↑, 1,   SOD2↑, 1,  

Metal & Cofactor Biology ⓘ

FTH1↑, 1,   IronCh↑, 1,  

Core Metabolism/Glycolysis ⓘ

Acetyl-CoA↑, 1,   GlucoseCon↑, 1,   Glycolysis↑, 1,   NAD↑, 1,   NADPH↑, 1,   SIRT1↑, 3,  

Cell Death ⓘ

Apoptosis↓, 1,   iNOS↓, 1,   MAPK↓, 1,  

Transcription & Epigenetics ⓘ

Ach↑, 1,   other↓, 1,   other↑, 1,  

Protein Folding & ER Stress ⓘ

ER Stress↓, 1,  

DNA Damage & Repair ⓘ

P53↓, 1,  

Cell Cycle & Senescence ⓘ

E2Fs↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

ERK↓, 1,   FGF↑, 1,   IGF-1R↓, 1,   p‑mTOR↓, 1,  

Migration ⓘ

AntiAg↑, 2,   AP-1↓, 1,   Ca+2↓, 1,   ITGB1↑, 1,   MMP2↓, 2,   TGF-β↓, 1,   TIMP1↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↑, 3,   Hif1a↑, 2,   PDGFR-BB↓, 1,   VEGF↓, 1,   VEGF↑, 1,   VEGFR2↑, 1,  

Barriers & Transport ⓘ

BBB↑, 2,  

Immune & Inflammatory Signaling ⓘ

COX1↓, 1,   COX2↓, 3,   IL2↓, 1,   IL5↓, 1,   IL6↓, 2,   IL8↓, 2,   Inflam↓, 11,   JAK↓, 1,   NF-kB↓, 2,   TNF-α↓, 3,   VitD↑, 1,  

Synaptic & Neurotransmission ⓘ

ChAT↑, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 3,   BioAv↑, 3,   BioAv↝, 4,   Dose↝, 1,   Half-Life↓, 1,   Half-Life↑, 1,   Half-Life↝, 1,  

Clinical Biomarkers ⓘ

AST↓, 1,   BP↓, 1,   GutMicro↑, 2,   IL6↓, 2,   VitD↑, 1,  

Functional Outcomes ⓘ

AntiAge↑, 1,   AntiCan↑, 3,   cardioP↑, 13,   cognitive↑, 1,   hepatoP↓, 1,   hepatoP↑, 2,   memory↑, 2,   neuroP↑, 7,   RenoP↓, 1,   Weight↓, 1,  
Total Targets: 85

Scientific Paper Hit Count for: cardioP, cardioProtective
3 EGCG (Epigallocatechin Gallate)
2 doxorubicin
1 Alpha-Lipoic-Acid
1 Apigenin (mainly Parsley)
1 Aspirin -acetylsalicylic acid
1 Ashwagandha(Withaferin A)
1 Boron
1 Cinnamon
1 Hydrogen Gas
1 Magnetic Fields
1 Naringin
1 Propolis -bee glue
1 Quercetin
1 Resveratrol
1 Silymarin (Milk Thistle) silibinin
1 Taurine
1 Thymoquinone
1 Vitamin B3,Niacin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:0  Cells:%  prod#:%  Target#:1188  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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