SMAD4 Cancer Research Results
SMAD4, SMAD family member 4: Click to Expand ⟱
| Source: CGL-Driver Genes |
| Type: TSG |
SMAD4 is a critical tumor suppressor gene that plays a significant role in the TGF-β signaling pathway, which regulates various cellular processes, including cell growth, differentiation, and apoptosis.
Plays a critical role in the TGF-beta signaling pathway.
|
NA, Not Available: Click to Expand ⟱
Scientific Papers found: Click to Expand⟱
*VEGF↑, *BMPs↓, *SMAD4↑, *SMAD5↑, *Ca+2↑,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Total Targets: 0
Pathway results for Effect on Normal Cells:
Migration ⓘ
Ca+2↑, 1, SMAD4↑, 1, SMAD5↑, 1,
Angiogenesis & Vasculature ⓘ
VEGF↑, 1,
Clinical Biomarkers ⓘ
BMPs↓, 1,
Total Targets: 5
Scientific Paper Hit Count for: SMAD4, SMAD family member 4
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:0 Cells:% prod#:% Target#:284 State#:% Dir#:2
wNotes=0 sortOrder:rid,rpid
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