BMPs Cancer Research Results

BMPs, Bone morphogenetic protein: Click to Expand ⟱
Source:
Type:
BMPs are important cytokines belonging to the Transforming Growth Factor (TGF)-β superfamily. BMP2 is highly overexpressed in human non-small cell lung cancer (NSCLC) and correlates with tumor stage and metastatic burden. BMP-2 level from patients with bone metastasis is significantly higher compared to patients without bone metastasis.
BMPs display significantly higher expression in tumors, which have been used as new biomarkers for the prognosis of cancer patients.
However, some data revealed an opposite role of BMP signaling in tumors. BMP-10 was downregulated in gastric cancer samples. BMP-6 expression was also absent in breast cancer tissues and might suppress breast cancer metastasis.
NA, Not Available: Click to Expand ⟱
none (reserved)
Scientific Papers found: Click to Expand⟱
4149- MF,    Pulsed Electro-Magnetic Field (PEMF) Effect on Bone Healing in Animal Models: A Review of Its Efficacy Related to Different Type of Damage
- Review, NA, NA
*other↑, *BDNF↑, *BMPs↑, *BMD↑,
498- MF,    Stimulation of osteogenic differentiation in human osteoprogenitor cells by pulsed electromagnetic fields: an in vitro study
- in-vitro, NA, NA
Calcium↑, MMP1↑, MMP3↑, BMPs↑,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Migration ⓘ

MMP1↑, 1,   MMP3↑, 1,  

Clinical Biomarkers ⓘ

BMPs↑, 1,   Calcium↑, 1,  
Total Targets: 4

Pathway results for Effect on Normal Cells:


Transcription & Epigenetics ⓘ

other↑, 1,  

Synaptic & Neurotransmission ⓘ

BDNF↑, 1,  

Clinical Biomarkers ⓘ

BMD↑, 1,   BMPs↑, 1,  
Total Targets: 4

Scientific Paper Hit Count for: BMPs, Bone morphogenetic protein
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:0  Cells:%  prod#:%  Target#:512  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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