TumCD Cancer Research Results

TumCD, Tumor Cell Death: Click to Expand ⟱
Source:
Type:
Tumor Cell Death
NA, Not Available: Click to Expand ⟱
none (reserved)
Scientific Papers found: Click to Expand⟱
1596- Cu,  CDT,    Unveiling the promising anticancer effect of copper-based compounds: a comprehensive review
- Review, NA, NA
TumCD↑, Apoptosis↓, ROS↑, angioG↑, Cupro↑, Paraptosis↑, eff↑, eff↓, selectivity↑, DNAdam↑, eff↑, eff↑, eff↑, eff↑, Fenton↑, H2O2↑, eff↑, eff↑, eff↑, RadioS↑, ChemoSen↑, eff↑, *toxicity↝, other↑, eff↑,
2073- HNK,    Honokiol induces apoptosis and autophagy via the ROS/ERK1/2 signaling pathway in human osteosarcoma cells in vitro and in vivo
- in-vitro, OS, U2OS - in-vivo, NA, NA
TumCD↑, TumAuto↑, Apoptosis↑, TumCCA↑, GRP78/BiP↑, ROS↑, eff↓, p‑ERK↑, selectivity↑, Ca+2↑, MMP↓, Casp3↑, Casp9↑, cl‑PARP↑, Bcl-2↓, Bcl-xL↓, survivin↓, LC3B-II↑, ATG5↑, TumVol↓, TumW↓, ER Stress↑,
2923- LT,    Luteolin induces apoptosis through endoplasmic reticulum stress and mitochondrial dysfunction in Neuro-2a mouse neuroblastoma cells
- in-vitro, NA, NA
Apoptosis↑, TumCD↑, Casp12↑, Casp9↑, Casp3↑, ER Stress↑, CHOP↑, GRP78/BiP↑, GRP94↑, cl‑ATF6↑, p‑eIF2α↑, MMP↓, JNK↓, p38↑, ERK↑, Cyt‑c↑,
523- MF,  MTX,    Extremely low-frequency magnetic fields significantly enhance the cytotoxicity of methotrexate and can reduce migration of cancer cell lines via transiently induced plasma membrane damage
- in-vitro, AML, THP1 - in-vitro, NA, PC12 - in-vivo, Cerv, HeLa
H2O2↑, TumCD↑, CellMemb↑, eff↑,
595- MFrot,  VitC,  MF,    The Effect of Alternating Magnetic Field Exposure and Vitamin C on Cancer Cells
- in-vitro, PC, MIA PaCa-2 - in-vitro, CRC, SW-620 - in-vitro, NA, HT1080 - in-vitro, Pca, PC3 - in-vitro, OS, U2OS - in-vitro, BC, MCF-7 - in-vitro, Nor, CCD-18Co
TumCD↑, eff↑, *TumCG∅,
1732- SFN,    Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells
- in-vitro, BC, MCF-7 - in-vitro, BC, SUM159 - in-vivo, NA, NA
TumCD↑, CSCs↓, Wnt↓, β-catenin/ZEB1↓, *BioAv↑, angioG↓, VEGF↓, Hif1a↓, MMP2↓, MMP9↓, Casp3↑, *Half-Life∅,
611- VitC,    Characterization of a new malignant human T-cell line (PFI-285) sensitive to ascorbic acid
- in-vitro, NA, NA
TumCD↑,
600- VitC,  VitK3,    Serum markers variation consistent with autoschizis induced by ascorbic acid-menadione in patients with prostate cancer
- in-vitro, NA, NA
autoS↑, TumCD↑,
628- VitC,  Mg,    Enhanced Anticancer Effect of Adding Magnesium to Vitamin C Therapy: Inhibition of Hormetic Response by SVCT-2 Activation
- in-vivo, Colon, CT26 - in-vitro, NA, MCF-7 - in-vitro, NA, SkBr3
AntiCan↑, SVCT-2↝, TumCD↑, ROS↑, P21↑, proCasp3↑, TumVol↓, DNAdam↑, NAD↓,

Showing Research Papers: 1 to 9 of 9

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 9

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Fenton↑, 1,   H2O2↑, 2,   ROS↑, 3,  

Mitochondria & Bioenergetics ⓘ

MMP↓, 2,  

Core Metabolism/Glycolysis ⓘ

NAD↓, 1,  

Cell Death ⓘ

Apoptosis↓, 1,   Apoptosis↑, 2,   autoS↑, 1,   Bcl-2↓, 1,   Bcl-xL↓, 1,   Casp12↑, 1,   Casp3↑, 3,   proCasp3↑, 1,   Casp9↑, 2,   Cupro↑, 1,   Cyt‑c↑, 1,   JNK↓, 1,   p38↑, 1,   Paraptosis↑, 1,   survivin↓, 1,   TumCD↑, 9,  

Transcription & Epigenetics ⓘ

other↑, 1,  

Protein Folding & ER Stress ⓘ

cl‑ATF6↑, 1,   CHOP↑, 1,   p‑eIF2α↑, 1,   ER Stress↑, 2,   GRP78/BiP↑, 2,   GRP94↑, 1,  

Autophagy & Lysosomes ⓘ

ATG5↑, 1,   LC3B-II↑, 1,   TumAuto↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 2,   cl‑PARP↑, 1,  

Cell Cycle & Senescence ⓘ

P21↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

CSCs↓, 1,   ERK↑, 1,   p‑ERK↑, 1,   Wnt↓, 1,  

Migration ⓘ

Ca+2↑, 1,   MMP2↓, 1,   MMP9↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 1,   angioG↑, 1,   Hif1a↓, 1,   VEGF↓, 1,  

Barriers & Transport ⓘ

CellMemb↑, 1,   SVCT-2↝, 1,  

Drug Metabolism & Resistance ⓘ

ChemoSen↑, 1,   eff↓, 2,   eff↑, 12,   RadioS↑, 1,   selectivity↑, 2,  

Functional Outcomes ⓘ

AntiCan↑, 1,   TumVol↓, 2,   TumW↓, 1,  
Total Targets: 57

Pathway results for Effect on Normal Cells:


Proliferation, Differentiation & Cell State ⓘ

TumCG∅, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 1,   Half-Life∅, 1,  

Functional Outcomes ⓘ

toxicity↝, 1,  
Total Targets: 4

Scientific Paper Hit Count for: TumCD, Tumor Cell Death
4 Vitamin C (Ascorbic Acid)
2 Magnetic Fields
1 Copper and Cu NanoParticles
1 chemodynamic therapy
1 Honokiol
1 Luteolin
1 methotrexate
1 Magnetic Field Rotating
1 Sulforaphane (mainly Broccoli)
1 VitK3,menadione
1 Magnesium
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:0  Cells:%  prod#:%  Target#:619  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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