Bil Cancer Research Results

Bil, Bilirubin: Click to Expand ⟱
Source:
Type:
Bilirubin a yellow pigment formed by the breakdown of heme (from red blood cells), is traditionally known for its role in liver function and jaundice.
Bilirubin as an Antioxidant (Cancer Protection)
-Moderately elevated bilirubin levels are associated with reduced cancer risk
-Bilirubin or synthetic analogs (e.g. bilirubin nanoparticles) are being studied for, Cancer prevention, and Reducing chemo side effects via oxidative stress protection.

In contrast, very high bilirubin levels in patients often indicate:
-Liver metastasis or hepatocellular carcinoma (HCC)
HCC, Hepatocellular Carcinoma: Click to Expand ⟱
Hepatocellular Carcinoma
Scientific Papers found: Click to Expand⟱
6385- Eug,    Anticancer potential of eugenol in hepatocellular carcinoma through modulation of oxidative stress, inflammation, apoptosis, and proliferation mechanisms
- in-vivo, HCC, HepG2
tumCV↓, TumCMig↓, *ALAT↓, *AST↓, *ALP↓, *Bil↓, *CEA↓, *lipid-P↓, *TNF-α↓, *IL1β↓, NF-kB↓, CXCR3↓, HRAS↓, KRAS↓, Ki-67↓, *GSH↑, *GPx↑, *SOD↑, *NRF2↑, P53↑, BAX↑, DR4↑, DR5↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned ⓘ

CXCR3↓, 1,  

Cell Death ⓘ

BAX↑, 1,   DR4↑, 1,   DR5↑, 1,  

Transcription & Epigenetics ⓘ

tumCV↓, 1,  

DNA Damage & Repair ⓘ

P53↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

HRAS↓, 1,  

Migration ⓘ

Ki-67↓, 1,   KRAS↓, 1,   TumCMig↓, 1,  

Immune & Inflammatory Signaling ⓘ

NF-kB↓, 1,  

Clinical Biomarkers ⓘ

Ki-67↓, 1,   KRAS↓, 1,  
Total Targets: 13

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

Bil↓, 1,   GPx↑, 1,   GSH↑, 1,   lipid-P↓, 1,   NRF2↑, 1,   SOD↑, 1,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 1,  

Migration ⓘ

CEA↓, 1,  

Immune & Inflammatory Signaling ⓘ

IL1β↓, 1,   TNF-α↓, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 1,   ALP↓, 1,   AST↓, 1,   Bil↓, 1,   CEA↓, 1,  
Total Targets: 15

Scientific Paper Hit Count for: Bil, Bilirubin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:10  Cells:%  prod#:%  Target#:1355  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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