TumCD Cancer Research Results

TumCD, Tumor Cell Death: Click to Expand ⟱
Source:
Type:
Tumor Cell Death
HCC, Hepatocellular Carcinoma: Click to Expand ⟱
Hepatocellular Carcinoma
Scientific Papers found: Click to Expand⟱
5259- 3BP,    Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP
- in-vivo, HCC, NA
ATP↓, TumCD↑, toxicity↓, eff↑, tumCV↓, Dose↝,
339- AgNPs,    Cancer cell specific cytotoxic potential of the silver nanoparticles synthesized using the endophytic fungus, Penicillium citrinum CGJ-C2
- in-vitro, BC, MCF-7 - in-vitro, Melanoma, A431 - in-vitro, HCC, HepG2
TumCD↑,
5008- DSF,  Cu,    Overcoming the compensatory elevation of NRF2 renders hepatocellular carcinoma cells more vulnerable to disulfiram/copper-induced ferroptosis
- in-vitro, HCC, NA
selectivity↑, TumCD↑, TumCMig↓, TumCI↓, angioG↓, mtDam↑, Iron↑, lipid-P↑, Ferroptosis↑, NF-kB↑, p‑p62↑, Keap1↓, eff↑, eff↓, ChemoSen↑,
6576- EU,    Eurycomanone induce apoptosis in HepG2 cells via up-regulation of p53
- in-vitro, HCC, HepG2
TumCD↑, selectivity↑, Apoptosis↓, ChrMod↑, DNAdam↑, P53↑, BAX↑, Bcl-2↓, Cyt‑c↑, eff↑, TumCCA↑,

Showing Research Papers: 1 to 4 of 4

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Ferroptosis↑, 1,   Iron↑, 1,   Keap1↓, 1,   lipid-P↑, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↓, 1,   mtDam↑, 1,  

Cell Death ⓘ

Apoptosis↓, 1,   BAX↑, 1,   Bcl-2↓, 1,   Cyt‑c↑, 1,   Ferroptosis↑, 1,   TumCD↑, 4,  

Transcription & Epigenetics ⓘ

ChrMod↑, 1,   tumCV↓, 1,  

Autophagy & Lysosomes ⓘ

p‑p62↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 1,   P53↑, 1,  

Cell Cycle & Senescence ⓘ

TumCCA↑, 1,  

Migration ⓘ

TumCI↓, 1,   TumCMig↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 1,  

Immune & Inflammatory Signaling ⓘ

NF-kB↑, 1,  

Drug Metabolism & Resistance ⓘ

ChemoSen↑, 1,   Dose↝, 1,   eff↓, 1,   eff↑, 3,   selectivity↑, 2,  

Functional Outcomes ⓘ

toxicity↓, 1,  
Total Targets: 28

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: TumCD, Tumor Cell Death
1 3-bromopyruvate
1 Silver-NanoParticles
1 Disulfiram
1 Copper and Cu NanoParticles
1 Eurycomanone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:10  Cells:%  prod#:%  Target#:619  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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