tumCV Cancer Research Results

tumCV, Cell Viability: Click to Expand ⟱
Source:
Type:
Cell Viability


HNSCC, Head and Neck Squamous Cell Carcinoma: Click to Expand ⟱
Head and Neck Squamous Cell Carcinoma

Scientific Papers found: Click to Expand⟱
5697- BRU,    Brusatol, a Nrf2 Inhibitor Targets STAT3 Signaling Cascade in Head and Neck Squamous Cell Carcinoma
- in-vitro, HNSCC, NA
NRF2↓, STAT3↓, proCasp3↑, cl‑PARP↑, Bcl-2↓, Bcl-xL↓, survivin↓, Hif1a↓, cMyc↓, JNK↑, MAPK↑, tumCV↓, ROS∅,
2976- CUR,    Curcumin suppresses the proliferation of oral squamous cell carcinoma through a specificity protein 1/nuclear factor‑κB‑dependent pathway
- in-vitro, Oral, HSC3 - in-vitro, HNSCC, CAL33
tumCV↓, Sp1/3/4↓, p65↓, HSF1↓, NF-kB↓,
4522- HNK,  MAG,    Honokiol Is More Potent than Magnolol in Reducing Head and Neck Cancer Cell Growth
- in-vitro, HNSCC, FaDu
AntiCan↑, tumCV↓, eff↑, survivin↓, RadioS↑,
3016- RosA,    Rosmarinic Acid Inhibits Cell Growth and Migration in Head and Neck Squamous Cell Carcinoma Cell Lines by Attenuating Epidermal Growth Factor Receptor Signaling
- in-vitro, HNSCC, UM-SCC-6 - in-vitro, HNSCC, UM-SCC-10B
chemoP↓, EGF↓, tumCV↓, TumCMig↓, ROS↓, PI3K↓, Akt↓, ERK↓, antiOx↑, p‑EGFR↓,
1476- SFN,  PDT,    Enhancement of cytotoxic effect on human head and neck cancer cells by combination of photodynamic therapy and sulforaphane
- in-vitro, HNSCC, NA
eff↑, tumCV↓, ROS↑, eff↓, Casp↑,
4887- ZER,  Rad,  Cisplatin,    Zerumbone acts as a radiosensitizer in head and neck squamous cell carcinoma
- in-vitro, HNSCC, CAL27
Apoptosis↑, ChemoSen↑, RadioS↑, tumCV↓,

Showing Research Papers: 1 to 6 of 6

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 6

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

antiOx↑, 1,   NRF2↓, 1,   ROS↓, 1,   ROS↑, 1,   ROS∅, 1,  

Mitochondria & Bioenergetics

EGF↓, 1,  

Core Metabolism/Glycolysis

cMyc↓, 1,  

Cell Death

Akt↓, 1,   Apoptosis↑, 1,   Bcl-2↓, 1,   Bcl-xL↓, 1,   Casp↑, 1,   proCasp3↑, 1,   JNK↑, 1,   MAPK↑, 1,   survivin↓, 2,  

Kinase & Signal Transduction

Sp1/3/4↓, 1,  

Transcription & Epigenetics

tumCV↓, 6,  

Protein Folding & ER Stress

HSF1↓, 1,  

DNA Damage & Repair

cl‑PARP↑, 1,  

Proliferation, Differentiation & Cell State

ERK↓, 1,   PI3K↓, 1,   STAT3↓, 1,  

Migration

TumCMig↓, 1,  

Angiogenesis & Vasculature

p‑EGFR↓, 1,   Hif1a↓, 1,  

Immune & Inflammatory Signaling

NF-kB↓, 1,   p65↓, 1,  

Drug Metabolism & Resistance

ChemoSen↑, 1,   eff↓, 1,   eff↑, 2,   RadioS↑, 2,  

Clinical Biomarkers

p‑EGFR↓, 1,  

Functional Outcomes

AntiCan↑, 1,   chemoP↓, 1,  
Total Targets: 35

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: tumCV, Cell Viability
1 brusatol
1 Curcumin
1 Honokiol
1 Magnolol
1 Rosmarinic acid
1 Sulforaphane (mainly Broccoli)
1 Photodynamic Therapy
1 Zerumbone
1 Radiotherapy/Radiation
1 Cisplatin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:13  Cells:%  prod#:%  Target#:897  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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