ROCK1 Cancer Research Results

ROCK1, Rho-associated coiled-coil containing protein kinase 1: Click to Expand ⟱
Source:
Type:
ROCK1 (Rho-associated coiled-coil containing protein kinase 1)
– ROCK1 is a serine/threonine kinase and a major effector of the Rho GTPase signaling pathway.

– Elevated expression of ROCK1 has been observed in various cancers, including breast, prostate, lung, colorectal, and gastric cancers.

– In many tumors, ROCK1 overexpression correlates with increased cell motility, invasion, and metastatic potential.
Liver, Liver Cancer: Click to Expand ⟱
Liver Cancer
Scientific Papers found: Click to Expand⟱
2762- BetA,    Targeting Effect of Betulinic Acid Liposome Modified by Hyaluronic Acid on Hepatoma Cells In Vitro
- in-vitro, Liver, HepG2
ROCK1↓, RAS↓, *BioAv↓, BioAv↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Proliferation, Differentiation & Cell State ⓘ

RAS↓, 1,  

Migration ⓘ

ROCK1↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 1,  
Total Targets: 3

Pathway results for Effect on Normal Cells:


Drug Metabolism & Resistance ⓘ

BioAv↓, 1,  
Total Targets: 1

Scientific Paper Hit Count for: ROCK1, Rho-associated coiled-coil containing protein kinase 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:14  Cells:%  prod#:%  Target#:1284  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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