HER2/EBBR2 Cancer Research Results

HER2/EBBR2, Human epidermal growth factor receptor 2: Click to Expand ⟱
Source:
Type:
Also called erbB-2 (or ERb-2) -Receptor tyrosine-protein kinase
HER2 is a protein that helps breast cancer cells grow quickly.
HER2/neu protein is a receptor tyrosine kinase that is normally involved in cell growth and division. However, in some cancers, the HER2/neu gene is overexpressed or mutated, leading to an overproduction of the protein. This can cause cells to grow and divide uncontrollably, leading to tumor formation.
Lung, Lung Cancer: Click to Expand ⟱
Lung CSC (Cancer Stem Cells) markers (CD133, CD44, ALDHA1, Nanog and Oct4)
Scientific Papers found: Click to Expand⟱
7213- GAs,    Anti-Cancer Properties of Ginkgolic Acids in Human Nasopharyngeal Carcinoma CNE-2Z Cells via Inhibition of Heat Shock Protein 90
- vitro+vivo, NPC, CNE2 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, MCF7 - in-vitro, Lung, H1975
ATPase↓, HSP90↓, TumCP↓, *toxicity↝, MMP2↓, MMP9↓, HER2/EBBR2↓, c-Raf↓, Akt↓, Bcl-2↓, other↝,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Mitochondria & Bioenergetics(tgid=3) ⓘ

c-Raf↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   Bcl-2↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

HER2/EBBR2↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↝, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

HSP90↓, 1,  

Migration(tgid=13) ⓘ

ATPase↓, 1,   MMP2↓, 1,   MMP9↓, 1,   TumCP↓, 1,  

Clinical Biomarkers(tgid=22) ⓘ

HER2/EBBR2↓, 1,  
Total Targets: 11

Pathway results for Effect on Normal Cells:


Functional Outcomes(tgid=23) ⓘ

toxicity↝, 1,  
Total Targets: 1

Scientific Paper Hit Count for: HER2/EBBR2, Human epidermal growth factor receptor 2
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:15  Cells:%  prod#:%  Target#:359  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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