Dose Cancer Research Results

Dose, Dosage: Click to Expand ⟱

Source:

Type:

Drug dosage vs efficacy, and actual dosage number of research papers.

Lung, Lung Cancer: Click to Expand ⟱

Lung CSC (Cancer Stem Cells) markers (CD133, CD44, ALDHA1, Nanog and Oct4)

Scientific Papers found: Click to Expand⟱

281-

ALA,

Reactive oxygen species mediate caspase activation and apoptosis induced by lipoic acid in human lung epithelial cancer cells through Bcl-2 down-regulation

in-vitro,

Lung,

H460

0-100uM

mt-ROS↑, Apoptosis↑, Casp9↑, Bcl-2↓, eff↓, eff↑, H2O2↑, Dose↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Redox & Oxidative Stress ⓘ

H2O2↑, 1, mt-ROS↑, 1,

Cell Death ⓘ

Apoptosis↑, 1, Bcl-2↓, 1, Casp9↑, 1,

Drug Metabolism & Resistance ⓘ

Dose↑, 1, eff↓, 1, eff↑, 1,
Total Targets: 8

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: Dose, Dosage

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells