miR-206 Cancer Research Results

miR-206, miR-206: Click to Expand ⟱
Source:
Type:
miR-206 is a well-characterized tumor-suppressor microRNA that plays major roles in cell differentiation, EMT suppression, metastasis inhibition, and therapy sensitivity across many cancers. It is best known as a myomiR (muscle-specific miRNA), but in cancer its loss has broad oncogenic consequences.
-Cancer: frequently downregulated
-miR-206 is a potent EMT suppressor

curcumin, resveratrol, quercetin may upregulate miR-206
Lung, Lung Cancer: Click to Expand ⟱
Lung CSC (Cancer Stem Cells) markers (CD133, CD44, ALDHA1, Nanog and Oct4)
Scientific Papers found: Click to Expand⟱
4710- CUR,    miR-206_and_suppression_of_PI3KAKTmTOR_signaling_pathway">Curcumin inhibits migration and invasion of non-small cell lung cancer cells through up-regulation of miR-206 and suppression of PI3K/AKT/mTOR signaling pathway
- in-vitro, Lung, A549
TumCMig↓, TumCI↓, miR-206↑, p‑mTOR↓, p‑Akt↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

p‑Akt↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

p‑mTOR↓, 1,  

Migration ⓘ

miR-206↑, 1,   TumCI↓, 1,   TumCMig↓, 1,  
Total Targets: 5

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: miR-206, miR-206
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:15  Cells:%  prod#:%  Target#:1393  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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