tumCV Cancer Research Results

tumCV, Cell Viability: Click to Expand ⟱
Source:
Type:
Cell Viability
MB, Medulloblastoma: Click to Expand ⟱
Medulloblastoma is an aggressive primary brain tumor that arises in the cerebellum of children and young adults.
Activation of these three pathways Akt/NF-kB, Shh, and Wnt/b-catenin converge in the upregulation of C-myc, N-myc, and Cyclin D1, three oncoproteins that play key roles in the development of medulloblastomas. High levels of these three oncoproteins were considered to be bad prognosis because they are related to unfavorable therapeutic outcome.
Scientific Papers found: Click to Expand⟱
7246- Gink,    Biflavone Ginkgetin, a Novel Wnt Inhibitor, Suppresses the Growth of Medulloblastoma
- in-vitro, GC, DAOY - in-vitro, MB, D283
Wnt↓, tumCV↓, TumCCA↑, Axin2↓, cycD1/CCND1↓, survivin↓, β-catenin/ZEB1↓,
1737- MFrot,  Fe,  MF,    Feature Matching of Microsecond-Pulsed Magnetic Fields Combined with Fe3O4 Particles for Killing A375 Melanoma Cells
- in-vitro, MB, A375
Dose∅, tumCV↓,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death(tgid=5) ⓘ

survivin↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

tumCV↓, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Axin2↓, 1,   Wnt↓, 1,  

Migration(tgid=13) ⓘ

β-catenin/ZEB1↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose∅, 1,  
Total Targets: 8

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: tumCV, Cell Viability
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:16  Cells:%  prod#:%  Target#:897  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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