TumCMig Cancer Research Results
TumCMig, Tumor cell migration: Click to Expand ⟱
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Tumor cell migration is a critical process in cancer progression and metastasis, which is the spread of cancer cells from the primary tumor to distant sites in the body.
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NSCLC, Non-small Cell Lung Cancer: Click to Expand ⟱
Non-small Cell Lung Cancer
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Scientific Papers found: Click to Expand⟱
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vitro+vivo, |
NSCLC, |
H1299 |
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in-vitro, |
NSCLC, |
A549 |
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TumCP↓, TumCMig↓, TumCI↓, Apoptosis↑, BAX↑, Bcl-2↓, EMT↓, p‑STAT3↓, TumCG↓,
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vitro+vivo, |
NSCLC, |
A549 |
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vitro+vivo, |
NSCLC, |
H1299 |
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TumCCA↑, CSCs↓, TumCI↓, TumCMig↓, TumCG↓, Wnt/(β-catenin)↓, Nanog↓, SOX2↓, OCT4↓, N-cadherin↓, Vim↓, E-cadherin↑,
TumCMig↓, TumCI↓, PI3K↓, Akt↓, MDM2↓, TumCP↓, TumMeta↓,
TumCMig↓, TumCP↓, Apoptosis↑, TFAP2A↓, hTERT/TERT↓, NF-kB↓, COX2↓, Hif1a↓, VEGF↓, Akt↓, p‑ERK↓, Cyt‑c↑, cl‑Casp↑, cl‑PARP↑, PI3K↓, Akt↓, Raf↓, MEK↓, ERK↓,
AntiCan↑, Dose↝, TumCCA↑, mt-Apoptosis↑, TumCMig↓, PI3K↓, Akt↓,
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in-vitro, |
NSCLC, |
Calu-1 |
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TumCP↓, PCNA↓, Ki-67↓, MCM2↓, Bcl-2↓, BAX↑, cl‑Casp3↑, TumCMig↓, TumCI↓, Hif1a↓, VEGF↓,
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in-vitro, |
NSCLC, |
A549 |
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in-vitro, |
Nor, |
WI38 |
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TumCP↓, TumCCA↑, selectivity↑, ROS↑, MMP↓, eff↓, TumCMig↓, eff↑,
Showing Research Papers: 1 to 7 of 7
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 7
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
ROS↑, 1,
Mitochondria & Bioenergetics ⓘ
MEK↓, 1, MMP↓, 1, Raf↓, 1,
Cell Death ⓘ
Akt↓, 4, Apoptosis↑, 2, mt-Apoptosis↑, 1, BAX↑, 2, Bcl-2↓, 2, cl‑Casp↑, 1, cl‑Casp3↑, 1, Cyt‑c↑, 1, hTERT/TERT↓, 1, MDM2↓, 1,
DNA Damage & Repair ⓘ
cl‑PARP↑, 1, PCNA↓, 1,
Cell Cycle & Senescence ⓘ
TFAP2A↓, 1, TumCCA↑, 3,
Proliferation, Differentiation & Cell State ⓘ
CSCs↓, 1, EMT↓, 1, ERK↓, 1, p‑ERK↓, 1, MCM2↓, 1, Nanog↓, 1, OCT4↓, 1, PI3K↓, 3, SOX2↓, 1, p‑STAT3↓, 1, TumCG↓, 2, Wnt/(β-catenin)↓, 1,
Migration ⓘ
E-cadherin↑, 1, Ki-67↓, 1, N-cadherin↓, 1, TumCI↓, 4, TumCMig↓, 7, TumCP↓, 5, TumMeta↓, 1, Vim↓, 1,
Angiogenesis & Vasculature ⓘ
Hif1a↓, 2, VEGF↓, 2,
Immune & Inflammatory Signaling ⓘ
COX2↓, 1, NF-kB↓, 1,
Drug Metabolism & Resistance ⓘ
Dose↝, 1, eff↓, 1, eff↑, 1, selectivity↑, 1,
Clinical Biomarkers ⓘ
hTERT/TERT↓, 1, Ki-67↓, 1,
Functional Outcomes ⓘ
AntiCan↑, 1,
Total Targets: 49
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: TumCMig, Tumor cell migration
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:19 Cells:% prod#:% Target#:326 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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