K+ Cancer Research Results

K+, K+ Ion Concentration: Click to Expand ⟱
Source:
Type:

K+ Ion Concentration - Potassium Ion Concentration

Type: Ion concentration / cellular homeostasis biomarker

Function: Potassium is the major intracellular cation and is essential for membrane potential, electrical excitability, cell-volume regulation, mitochondrial function, enzyme activity, apoptosis, and inflammatory signaling. Changes in K+ concentration are closely coupled to the activity of potassium channels, transporters, and membrane pumps.

Cancer: ↕ Context- and compartment-dependent. Cancer cells can maintain high intracellular K+ to support proliferation and resistance to apoptosis, whereas intracellular K+ loss through K+ efflux can promote apoptotic signaling. Elevated extracellular K+ within the tumor microenvironment can also suppress T-cell function and contribute to tumor immune evasion.
AML, Acute Myeloid Leukemia: Click to Expand ⟱
Acute Myeloid Leukemia
Scientific Papers found: Click to Expand⟱
7387- MF,    Effects of Sinusoidal Magnetic Field Observed on Cell Proliferation, Ion Concentration, and Osmolarity in Two Human Cancer Cell Lines
- in-vitro, AML, HL-60 - in-vitro, adrenal, SK-HEP-1
Dose↝, TumCG↓, Na+↑, K+↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

K+↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

TumCG↓, 1,  

Migration(tgid=13) ⓘ

Na+↑, 1,  

Barriers & Transport(tgid=15) ⓘ

Na+↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 1,  
Total Targets: 5

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: K+, K+ Ion Concentration
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:2  Cells:%  prod#:%  Target#:1635  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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