AntiCan Cancer Research Results

AntiCan, Anticancer Effect: Click to Expand ⟱
Source:
Type: general indicator
Anticancer Effect


AML, Acute Myeloid Leukemia: Click to Expand ⟱
Acute Myeloid Leukemia
Scientific Papers found: Click to Expand⟱
5377- ART/DHA,    Dihydroartemisinin-induced ferroptosis in acute myeloid leukemia: links to iron metabolism and metallothionein
- in-vitro, AML, NA
AntiCan↑, Ferroptosis↑, Iron↑, Mets↑, eff↑, GSH↝, eff↑, other↓, eff↑, other↓,
5634- BCA,    Molecular Mechanisms of Biochanin A in AML Cells: Apoptosis Induction and Pathway-Specific Regulation in U937 and THP-1
- in-vitro, AML, U937 - in-vitro, AML, THP1
Apoptosis↑, Casp7↑, PARP1↑, Bcl-2↓, Myc↓, CHOP/DDIT3↑, P21↑, p62↑, TumCCA↑, TXNIP↑, ROS↑, *antiOx↑, *Inflam↓, *neuroP↑, AntiCan↑, TumCP↓, angioG↓, TumMeta↓, VEGF↓, MMPs↓, tumCV↓, DNAdam↑, CHOP/DDIT3↑, cMyc↓, BioAv↓, Half-Life↓, BioAv↑,
6525- CRV,    D-carvone induced ROS mediated apoptotic cell death in human leukemic cell lines (Molt-4)
- in-vitro, AML, NA
tumCV↓, ROS↑, antiOx↓, MMP↓, Apoptosis↑, Casp8↑, Casp9↑, Casp3↑, *neuroP↑, AntiCan↑, *AntiArt↑, TBARS↑, SOD↓, GSH↓, Catalase↓,
6319- DRE,    Efficient induction of extrinsic cell death by dandelion root extract in human chronic myelomonocytic leukemia (CMML) cells
- in-vitro, AML, MV411 - in-vitro, AML, HL-60
Apoptosis↑, TumAuto↑, *toxicity↓, selectivity↑, Casp8↑, MMP↓, *Inflam↓, *antiOx↑, *AntiCan↑, DNAdam↑, cl‑Casp3↑, tumCV↓, ROS↑,
3182- SFN,    Sulforaphane Modulates AQP8-Linked Redox Signalling in Leukemia Cells
- in-vitro, AML, NA
Prx↓, AQPs↓, NOX↓, tumCV↓, AntiCan↑, cardioP↑, neuroP↑, Inflam↓, chemoPv↑, angioG↓, TumMeta↓, selectivity↑, ROS↓,

Showing Research Papers: 1 to 5 of 5

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   Catalase↓, 1,   Ferroptosis↑, 1,   GSH↓, 1,   GSH↝, 1,   Iron↑, 1,   Mets↑, 1,   Prx↓, 1,   ROS↓, 1,   ROS↑, 3,   SOD↓, 1,   TBARS↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MMP↓, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

cMyc↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 3,   Bcl-2↓, 1,   Casp3↑, 1,   cl‑Casp3↑, 1,   Casp7↑, 1,   Casp8↑, 2,   Casp9↑, 1,   Ferroptosis↑, 1,   Myc↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↓, 2,   tumCV↓, 4,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 2,  

Autophagy & Lysosomes(tgid=9) ⓘ

p62↑, 1,   TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 2,   PARP1↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

P21↑, 1,   TumCCA↑, 1,  

Migration(tgid=13) ⓘ

MMPs↓, 1,   TumCP↓, 1,   TumMeta↓, 2,   TXNIP↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 2,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

AQPs↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Inflam↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

NOX↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 1,   eff↑, 3,   Half-Life↓, 1,   selectivity↑, 2,  

Clinical Biomarkers(tgid=22) ⓘ

Myc↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 4,   cardioP↑, 1,   chemoPv↑, 1,   neuroP↑, 1,  
Total Targets: 51

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiArt↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Inflam↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   neuroP↑, 2,   toxicity↓, 1,  
Total Targets: 6

Scientific Paper Hit Count for: AntiCan, Anticancer Effect
1 Artemisinin
1 Biochanin A
1 Carvone
1 Dandelion Root
1 Sulforaphane (mainly Broccoli)
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:2  Cells:%  prod#:%  Target#:813  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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