| Source: |
| Type: |
| The term "IL-1" is often used as an umbrella term for the interleukin-1 family, which includes multiple cytokines. The two best-known members are IL-1α and IL-1β. IL-1β is secreted from cells and plays a major systemic role in inflammation. It is a crucial mediator in the inflammatory response and is involved in the fever response, activation of endothelial cells, and leukocyte recruitment. Its increased expression is commonly linked to: – Promotion of a pro-inflammatory microenvironment that supports tumor growth. – Enhanced angiogenesis, invasion, and metastasis. – Recruitment of myeloid cells that may further suppress antitumor immunity. High expression of either tends to be associated with a more aggressive phenotype and worse prognosis in many cancer types. |
| Ovarian Cancer |
| 7393- | Amla, | Emblica officinalis extract induces autophagy and inhibits human ovarian cancer cell proliferation, angiogenesis, growth of mouse xenograft tumors |
| - | vitro+vivo, | Ovarian, | OVCAR-3 | - | in-vitro, | Ovarian, | SW626 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:20 Cells:% prod#:% Target#:978 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid