other Cancer Research Results
other, other: Click to Expand ⟱
PC, Pancreatic Cancer: Click to Expand ⟱
Pancreatic Cancer: Hypoxia (low oxygen tension) is commonly found in solid tumors. Hypoxia-inducible factor-1 (HIF-1),is a key mediator of the cellular response to hypoxia and is overexpressed in a wide variety of solid tumors, including pancreatic cancer.
Nanog is highly expressed in CSCs compared to normal cells [93–97]
HIF-1↑
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Scientific Papers found: Click to Expand⟱
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Trial, |
NSCLC, |
NA |
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- |
Trial, |
PC, |
NA |
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- |
Trial, |
HCC, |
NA |
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Dose↝, toxicity↓, other↓, QoL↑, OS?,
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vitro+vivo, |
PC, |
MS-1 |
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- |
vitro+vivo, |
PC, |
HUVECs |
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other↓, TumCP↓, TumCMig↓, VEGFR2↓, TumVol↓, HSP70/HSPA5↓, HSP90↓, TumCCA↑, angioG↓,
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in-vitro, |
BC, |
MDA-MB-231 |
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- |
in-vitro, |
PC, |
PANC1 |
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in-vitro, |
Pca, |
DU145 |
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TumCCA↑, cycD1/CCND1↓, Bcl-xL↓, Mcl-1↓, other↓,
Showing Research Papers: 1 to 3 of 3
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3
Pathway results for Effect on Cancer / Diseased Cells:
Cell Death ⓘ
Bcl-xL↓, 1, Mcl-1↓, 1,
Transcription & Epigenetics ⓘ
other↓, 3,
Protein Folding & ER Stress ⓘ
HSP70/HSPA5↓, 1, HSP90↓, 1,
Cell Cycle & Senescence ⓘ
cycD1/CCND1↓, 1, TumCCA↑, 2,
Migration ⓘ
TumCMig↓, 1, TumCP↓, 1,
Angiogenesis & Vasculature ⓘ
angioG↓, 1, VEGFR2↓, 1,
Drug Metabolism & Resistance ⓘ
Dose↝, 1,
Functional Outcomes ⓘ
OS?, 1, QoL↑, 1, toxicity↓, 1, TumVol↓, 1,
Total Targets: 16
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: other, other
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:21 Cells:% prod#:% Target#:767 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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