Inflam Cancer Research Results
Inflam, inflammation: Click to Expand ⟱
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Cancer and inflammation are closely linked, with chronic inflammation contributing to the development and progression of cancer. Various inflammatory mediators and cells are involved in this process.
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PC, Pancreatic Cancer: Click to Expand ⟱
Pancreatic Cancer: Hypoxia (low oxygen tension) is commonly found in solid tumors. Hypoxia-inducible factor-1 (HIF-1),is a key mediator of the cellular response to hypoxia and is overexpressed in a wide variety of solid tumors, including pancreatic cancer.
Nanog is highly expressed in CSCs compared to normal cells [93–97]
HIF-1↑
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Scientific Papers found: Click to Expand⟱
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in-vitro, |
Colon, |
HT29 |
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in-vitro, |
CRC, |
HCT116 |
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in-vitro, |
PC, |
COLO357 |
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Human, |
Colon, |
NA |
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TumCG↓, eff↑, ChemoSen↑, Apoptosis↑, TumVol↓, TumW↓, *Inflam↓, *antiOx↓, BioAv↝,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Cell Death ⓘ
Apoptosis↑, 1,
Proliferation, Differentiation & Cell State ⓘ
TumCG↓, 1,
Drug Metabolism & Resistance ⓘ
BioAv↝, 1, ChemoSen↑, 1, eff↑, 1,
Functional Outcomes ⓘ
TumVol↓, 1, TumW↓, 1,
Total Targets: 7
Pathway results for Effect on Normal Cells:
Redox & Oxidative Stress ⓘ
antiOx↓, 1,
Immune & Inflammatory Signaling ⓘ
Inflam↓, 1,
Total Targets: 2
Scientific Paper Hit Count for: Inflam, inflammation
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:21 Cells:% prod#:% Target#:953 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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