chemoP Cancer Research Results
chemoP, ChemoProtective: Click to Expand ⟱
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Protects normal cells against the effect of Chemo.
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PC, Pancreatic Cancer: Click to Expand ⟱
Pancreatic Cancer: Hypoxia (low oxygen tension) is commonly found in solid tumors. Hypoxia-inducible factor-1 (HIF-1),is a key mediator of the cellular response to hypoxia and is overexpressed in a wide variety of solid tumors, including pancreatic cancer.
Nanog is highly expressed in CSCs compared to normal cells [93–97]
HIF-1↑
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Scientific Papers found: Click to Expand⟱
chemoP↑, ChemoSen↑, 12LOX?, Bcl-2↓, BAX↑, Mcl-1↓, ERK↓, Prx6↑, Dose↝, BioAv↓, eff↑,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
Prx6↑, 1,
Core Metabolism/Glycolysis ⓘ
12LOX?, 1,
Cell Death ⓘ
BAX↑, 1, Bcl-2↓, 1, Mcl-1↓, 1,
Proliferation, Differentiation & Cell State ⓘ
ERK↓, 1,
Drug Metabolism & Resistance ⓘ
BioAv↓, 1, ChemoSen↑, 1, Dose↝, 1, eff↑, 1,
Functional Outcomes ⓘ
chemoP↑, 1,
Total Targets: 11
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: chemoP, ChemoProtective
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:21 Cells:% prod#:% Target#:1171 State#:% Dir#:2
wNotes=0 sortOrder:rid,rpid
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