Imm Cancer Research Results

Imm, immunostimulatory: Click to Expand ⟱
Source:
Type:
Enhance the immune response in patients.
PC, Pancreatic Cancer: Click to Expand ⟱
Pancreatic Cancer: Hypoxia (low oxygen tension) is commonly found in solid tumors. Hypoxia-inducible factor-1 (HIF-1),is a key mediator of the cellular response to hypoxia and is overexpressed in a wide variety of solid tumors, including pancreatic cancer.
Nanog is highly expressed in CSCs compared to normal cells [93–97]
HIF-1↑
Scientific Papers found: Click to Expand⟱
6607- Ech,    Cytotoxic effects of Echinacea root hexanic extracts on human cancer cell lines
- in-vitro, PC, MIA PaCa-2 - in-vitro, CRC, Colo320
tumCV↓, eff↑, Apoptosis↑, Casp3↑, Casp7↑, DNAdam↑, Imm↑, NK cell↑, PGE2↓, COX1↓, COX2↓, 5LO↓,
5492- EP,    Nano-Pulse Stimulation Therapy in Oncology
- in-vivo, PC, Panc02 - in-vivo, BC, 4T1
CellMemb↑, Ca+2↑, DNAdam↑, eff↝, Imm↑,
7505- HCQ,  GEM,  PacT,    A Randomized Phase II Preoperative Study of Autophagy Inhibition with High-Dose Hydroxychloroquine and Gemcitabine/Nab-Paclitaxel in Pancreatic Cancer Patients
- Trial, PC, NA
eff↑, TumAuto↓, Imm↑, CA19-9↓, OS↑,

Showing Research Papers: 1 to 3 of 3

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death(tgid=5) ⓘ

Apoptosis↑, 1,   Casp3↑, 1,   Casp7↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

tumCV↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

TumAuto↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 2,  

Migration(tgid=13) ⓘ

5LO↓, 1,   Ca+2↑, 1,  

Barriers & Transport(tgid=15) ⓘ

CellMemb↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 1,   COX2↓, 1,   Imm↑, 3,   NK cell↑, 1,   PGE2↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

eff↑, 2,   eff↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

CA19-9↓, 1,  

Functional Outcomes(tgid=23) ⓘ

OS↑, 1,  
Total Targets: 18

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: Imm, immunostimulatory
1 Echinacea
1 Electrical Pulses
1 hydroxychloroquine
1 Gemcitabine (Gemzar)
1 Paclitaxel/Taxol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:21  Cells:%  prod#:%  Target#:1332  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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