Imm Cancer Research Results
Imm, immunostimulatory: Click to Expand ⟱
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| Type: |
Enhance the immune response in patients.
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PC, Pancreatic Cancer: Click to Expand ⟱
Pancreatic Cancer: Hypoxia (low oxygen tension) is commonly found in solid tumors. Hypoxia-inducible factor-1 (HIF-1),is a key mediator of the cellular response to hypoxia and is overexpressed in a wide variety of solid tumors, including pancreatic cancer.
Nanog is highly expressed in CSCs compared to normal cells [93–97]
HIF-1↑
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Scientific Papers found: Click to Expand⟱
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in-vitro, |
PC, |
MIA PaCa-2 |
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in-vitro, |
CRC, |
Colo320 |
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tumCV↓, eff↑, Apoptosis↑, Casp3↑, Casp7↑, DNAdam↑, Imm↑, NK cell↑, PGE2↓, COX1↓, COX2↓, 5LO↓,
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in-vivo, |
PC, |
Panc02 |
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in-vivo, |
BC, |
4T1 |
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CellMemb↑, Ca+2↑, DNAdam↑, eff↝, Imm↑,
Showing Research Papers: 1 to 2 of 2
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2
Pathway results for Effect on Cancer / Diseased Cells:
Cell Death ⓘ
Apoptosis↑, 1, Casp3↑, 1, Casp7↑, 1,
Transcription & Epigenetics ⓘ
tumCV↓, 1,
DNA Damage & Repair ⓘ
DNAdam↑, 2,
Migration ⓘ
5LO↓, 1, Ca+2↑, 1,
Barriers & Transport ⓘ
CellMemb↑, 1,
Immune & Inflammatory Signaling ⓘ
COX1↓, 1, COX2↓, 1, Imm↑, 2, NK cell↑, 1, PGE2↓, 1,
Drug Metabolism & Resistance ⓘ
eff↑, 1, eff↝, 1,
Total Targets: 15
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: Imm, immunostimulatory
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:21 Cells:% prod#:% Target#:1332 State#:% Dir#:2
wNotes=0 sortOrder:rid,rpid
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