Prx6 Cancer Research Results

Prx6, Peroxiredoxin 6: Click to Expand ⟱
Source:
Type: protein
PRDX6 (Peroxiredoxin 6) is a protein that plays a crucial role in maintaining cellular redox balance and protecting cells from oxidative damage.
PRDX6 has been found to have both tumor-suppressive and tumor-promoting roles, depending on the type of cancer and the cellular context.
PRDX6 can neutralize reactive oxygen species (ROS).
PC, Pancreatic Cancer: Click to Expand ⟱
Pancreatic Cancer: Hypoxia (low oxygen tension) is commonly found in solid tumors. Hypoxia-inducible factor-1 (HIF-1),is a key mediator of the cellular response to hypoxia and is overexpressed in a wide variety of solid tumors, including pancreatic cancer.
Nanog is highly expressed in CSCs compared to normal cells [93–97]
HIF-1↑
Scientific Papers found: Click to Expand⟱
2597- Ba,    Baicalein – An Intriguing Therapeutic Phytochemical in Pancreatic Cancer
- Review, PC, NA
chemoP↑, ChemoSen↑, 12LOX?, Bcl-2↓, BAX↑, Mcl-1↓, ERK↓, Prx6↑, Dose↝, BioAv↓, eff↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Prx6↑, 1,  

Core Metabolism/Glycolysis ⓘ

12LOX?, 1,  

Cell Death ⓘ

BAX↑, 1,   Bcl-2↓, 1,   Mcl-1↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

ERK↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 1,   ChemoSen↑, 1,   Dose↝, 1,   eff↑, 1,  

Functional Outcomes ⓘ

chemoP↑, 1,  
Total Targets: 11

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: Prx6, Peroxiredoxin 6
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:21  Cells:%  prod#:%  Target#:759  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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