eff Cancer Research Results
eff, efficacy: Click to Expand ⟱
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| Type: |
Power to enhance an anti cancer effect
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PC, Pancreatic Cancer: Click to Expand ⟱
Pancreatic Cancer: Hypoxia (low oxygen tension) is commonly found in solid tumors. Hypoxia-inducible factor-1 (HIF-1),is a key mediator of the cellular response to hypoxia and is overexpressed in a wide variety of solid tumors, including pancreatic cancer.
Nanog is highly expressed in CSCs compared to normal cells [93–97]
HIF-1↑
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Scientific Papers found: Click to Expand⟱
Dose↝, OS↑, eff↝,
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in-vivo, |
PC, |
Panc02 |
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in-vivo, |
BC, |
4T1 |
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CellMemb↑, Ca+2↑, DNAdam↑, eff↝, Imm↑,
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in-vitro, |
PC, |
PANC1 |
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in-vitro, |
PC, |
MIA PaCa-2 |
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in-vitro, |
PC, |
Bxpc-3 |
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TumCP↓, Apoptosis↑, pH↑, eff↝,
Showing Research Papers: 1 to 3 of 3
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3
Pathway results for Effect on Cancer / Diseased Cells:
Cell Death(tgid=5) ⓘ
Apoptosis↑, 1,
DNA Damage & Repair(tgid=10) ⓘ
DNAdam↑, 1,
Migration(tgid=13) ⓘ
Ca+2↑, 1, TumCP↓, 1,
Barriers & Transport(tgid=15) ⓘ
CellMemb↑, 1,
Immune & Inflammatory Signaling(tgid=16) ⓘ
Imm↑, 1,
Cellular Microenvironment(tgid=17) ⓘ
pH↑, 1,
Drug Metabolism & Resistance(tgid=21) ⓘ
Dose↝, 1, eff↝, 3,
Functional Outcomes(tgid=23) ⓘ
OS↑, 1,
Total Targets: 10
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: eff, efficacy
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:21 Cells:% prod#:% Target#:961 State#:% Dir#:4
wNotes=0 sortOrder:rid,rpid
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