p300 Cancer Research Results
p300, p300: Click to Expand ⟱
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p300 is a transcriptional coactivator protein that plays a crucial role in regulating gene expression, cell growth, and differentiation.
p300 has been shown to promote tumor initiation and progression by regulating the expression of genes involved in cell growth, survival, and metastasis.
p300 is overexpressed in various types of cancer, with poor prognosis.
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SCC, Squamous Cell Carcinoma: Click to Expand ⟱
Squamous Cell Carcinoma: Also known as epidermoid carcinomas, comprise a number of different types of cancer that begin in squamous cells. These cells form on the surface of the skin.
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Scientific Papers found: Click to Expand⟱
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vitro+vivo, |
SCC, |
KYSE150 |
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vitro+vivo, |
SCC, |
KYSE450 |
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HATs↓, TumCCA↑, Apoptosis↑, TumCMig↓, TumCI↓, CBP↓, p300↓, TGF-β↓, Ki-67↓, SMAD2↓, SMAD3↓,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Cell Death ⓘ
Apoptosis↑, 1, CBP↓, 1,
Transcription & Epigenetics ⓘ
HATs↓, 1,
Cell Cycle & Senescence ⓘ
TumCCA↑, 1,
Proliferation, Differentiation & Cell State ⓘ
p300↓, 1,
Migration ⓘ
Ki-67↓, 1, SMAD2↓, 1, SMAD3↓, 1, TGF-β↓, 1, TumCI↓, 1, TumCMig↓, 1,
Clinical Biomarkers ⓘ
Ki-67↓, 1,
Total Targets: 12
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: p300, p300
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:25 Cells:% prod#:% Target#:901 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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