OS Cancer Research Results

OS, overall survival: Click to Expand ⟱
Source:
Type:
Overall survival

GBM, Glioblastoma: Click to Expand ⟱
Glioblastoma is a fast-growing and aggressive brain tumor.

Scientific Papers found: Click to Expand⟱
333- AgNPs,  HPT,    Enhancement effect of cytotoxicity response of silver nanoparticles combined with thermotherapy on C6 rat glioma cells
- in-vivo, GBM, NA
OS↑,
332- AgNPs,  Rad,    Enhancement of Radiosensitization by Silver Nanoparticles Functionalized with Polyethylene Glycol and Aptamer As1411 for Glioma Irradiation Therapy
- in-vivo, GBM, NA
OS↑,
331- AgNPs,  Rad,    Silver nanoparticles: a novel radiation sensitizer for glioma?
- vitro+vivo, GBM, NA
OS↑,
7171- CHA,    Chaetocin-mediated SUV39H1 inhibition targets stemness and oncogenic networks of diffuse midline gliomas and synergizes with ONC201
- vitro+vivo, GBM, DIPG
TumCG↓, TumCP↓, Apoptosis↓, OS↑, H3K9↓, SUV39H↓, eff↑, CSCs↓, SOX9↓, HGF/c-Met↓, FGF21↓, EGFR↓, PDGFR-BB↓, Wnt↓, MYCN↑, OLIG2↓, AURKB↓, HO-1↑, P21↑,
6151- Chol,    Effect of Choline Alphoscerate on the Survival of Glioblastoma Patients: A Retrospective, Single-Center Study
- Study, GBM, NA
OS↑,
6153- CoQ10,    High levels of ubidecarenone (oxidized CoQ10) delivered using a drug-lipid conjugate nanodispersion (BPM31510) differentially affect redox status and growth in malignant glioma versus non-tumor cells
- vitro+vivo, GBM, U251
eff↑, selectivity↑, ROS↑, OS↑, TumCCA↑,
5487- EP,    High-frequency irreversible electroporation improves survival and immune cell infiltration in rodents with malignant gliomas
- in-vivo, GBM, NA
OS↑, CellMemb↑, Imm↑, Inflam↓, necrosis↑, Pyro↑, eff↑, IL2↑, IL6↑, IL17↑, IFN-γ↓,
2511- H2,    Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation
- in-vivo, GBM, U87MG
TumCG↓, OS↑, CD133↓, Ki-67↓, angioG↓, Diff↑, TumCMig↓, TumCI↓, Dose↝, BBB↑, mt-ROS↑,
1438- HCQ,  Chemo,    Adding Chloroquine to Conventional Treatment for Glioblastoma Multiforme
- Trial, GBM, NA
OS↑, *toxicity∅,
1922- JG,    Juglone induces apoptosis of tumor stem-like cells through ROS-p38 pathway in glioblastoma
- in-vitro, GBM, U87MG
tumCV↓, TumCP↓, ROS↑, p‑p38↑, eff↓, Apoptosis↑, OS↑,
2500- meben,    Antiparasitic mebendazole shows survival benefit in 2 preclinical models of glioblastoma multiforme
- in-vitro, GBM, U87MG - in-vivo, GBM, NA
α-tubulin↓, AntiCan↑, TumCG↓, OS↑, VEGF↓, Hif1a↓,
2260- MF,    Alternative magnetic field exposure suppresses tumor growth via metabolic reprogramming
- in-vitro, GBM, U87MG - in-vitro, GBM, LN229 - in-vivo, NA, NA
TumCP↓, TumCG↓, OS↑, ROS↑, SOD2↑, eff↓, ECAR↓, OCR↑, selectivity↑, *toxicity∅, TumVol↓, PGC-1α↑, OXPHOS↑, Glycolysis↓, PKM2↓,
529- MF,    Low-frequency magnetic field therapy for glioblastoma: Current advances, mechanisms, challenges and future perspectives
- Review, GBM, NA
Ca+2↑, ROS↑, ChemoSen↑, QoL↑, OS↑,
3493- MFrot,  MF,    Mechanical nanosurgery of chemoresistant glioblastoma using magnetically controlled carbon nanotubes
- in-vivo, GBM, NA
TumCD↑, MMP↓, Cyt‑c↑, Apoptosis↑, OS↑, DNAdam↑,
2259- MFrot,  MF,    Method and apparatus for oncomagnetic treatment
- in-vitro, GBM, NA
MMP↓, Bcl-2↓, BAX↑, Bak↑, Cyt‑c↑, Casp3↑, Casp9↑, DNAdam↑, ROS↑, lactateProd↑, Apoptosis↑, MPT↑, *selectivity↑, eff↑, MMP↓, selectivity↑, TCA?, H2O2↑, eff↑, *antiOx↑, H2O2↑, eff↓, GSH/GSSG↓, *toxicity∅, OS↑,
2258- MFrot,  MF,    EXTH-68. ONCOMAGNETIC TREATMENT SELECTIVELY KILLS GLIOMA CANCER CELLS BY INDUCING OXIDATIVE STRESS AND DNA DAMAGE
- in-vitro, GBM, GBM - in-vitro, Nor, SVGp12
TumVol↓, OS↑, γH2AX↑, DNAdam↑, selectivity↑, ROS↑, TumCD↑, eff↑, eff↓,
4569- MFrot,    Case Report: A new noninvasive device-based treatment of a mesencephalic H3 K27M glioma
- Case Report, GBM, NA
Dose↝, Dose↑, Dose↑, OS↑, toxicity↓, ETC↓, ROS↑,
1911- Nos,    Noscapine inhibits tumor growth in TMZ-resistant gliomas
- in-vitro, GBM, NA - in-vivo, GBM, NA
TumCG↓, TumCI↓, OS↑,
2025- PB,    Complete response of a recurrent, multicentric malignant glioma in a patient treated with phenylbutyrate
- Case Report, GBM, NA
Dose↝, OS↑,
2026- PB,    Oral sodium phenylbutyrate in patients with recurrent malignant gliomas: A dose escalation and pharmacologic study
- Trial, GBM, NA
Dose↝, Dose↑, Dose↝, OS↑, HDAC↓, TumCCA↑, P21↑, other↝, BioAv↑, eff↑,
5138- SAS,  Rad,    Drug repurposing: sulfasalazine sensitizes gliomas to gamma knife radiosurgery by blocking cystine uptake through system Xc-, leading to glutathione depletion
- vitro+vivo, GBM, NA
cystine↓, GSH↓, ROS↑, RadioS↑, eff↓, DNAdam↑, OS↑,
2412- TTT,    A review of tumor treating fields (TTFields): advancements in clinical applications and mechanistic insights
- Review, GBM, NA
TumCG↓, eff↝, OS↑,

Showing Research Papers: 1 to 22 of 22

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 22

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0)

AURKB↓, 1,   H3K9↓, 1,   MYCN↑, 1,   OLIG2↓, 1,   SUV39H↓, 1,  

Redox & Oxidative Stress(tgid=1)

cystine↓, 1,   GSH↓, 1,   GSH/GSSG↓, 1,   H2O2↑, 2,   HO-1↑, 1,   OXPHOS↑, 1,   ROS↑, 8,   mt-ROS↑, 1,   SOD2↑, 1,  

Mitochondria & Bioenergetics(tgid=3)

ETC↓, 1,   MMP↓, 3,   MPT↑, 1,   OCR↑, 1,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis(tgid=4)

ECAR↓, 1,   FGF21↓, 1,   Glycolysis↓, 1,   lactateProd↑, 1,   PKM2↓, 1,   TCA?, 1,  

Cell Death(tgid=5)

Apoptosis↓, 1,   Apoptosis↑, 3,   Bak↑, 1,   BAX↑, 1,   Bcl-2↓, 1,   Casp3↑, 1,   Casp9↑, 1,   Cyt‑c↑, 2,   HGF/c-Met↓, 1,   necrosis↑, 1,   p‑p38↑, 1,   Pyro↑, 1,   TumCD↑, 2,  

Kinase & Signal Transduction(tgid=6)

SOX9↓, 1,  

Transcription & Epigenetics(tgid=7)

other↝, 1,   tumCV↓, 1,  

DNA Damage & Repair(tgid=10)

DNAdam↑, 4,   γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11)

P21↑, 2,   TumCCA↑, 2,  

Proliferation, Differentiation & Cell State(tgid=12)

CD133↓, 1,   CSCs↓, 1,   Diff↑, 1,   HDAC↓, 1,   TumCG↓, 6,   Wnt↓, 1,  

Migration(tgid=13)

Ca+2↑, 1,   Ki-67↓, 1,   TumCI↓, 2,   TumCMig↓, 1,   TumCP↓, 3,   α-tubulin↓, 1,  

Angiogenesis & Vasculature(tgid=14)

angioG↓, 1,   EGFR↓, 1,   Hif1a↓, 1,   PDGFR-BB↓, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15)

BBB↑, 1,   CellMemb↑, 1,  

Immune & Inflammatory Signaling(tgid=16)

IFN-γ↓, 1,   IL17↑, 1,   IL2↑, 1,   IL6↑, 1,   Imm↑, 1,   Inflam↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↑, 1,   ChemoSen↑, 1,   Dose↑, 3,   Dose↝, 5,   eff↓, 5,   eff↑, 7,   eff↝, 1,   RadioS↑, 1,   selectivity↑, 4,  

Clinical Biomarkers(tgid=22)

EGFR↓, 1,   IL6↑, 1,   Ki-67↓, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 1,   OS↑, 22,   QoL↑, 1,   toxicity↓, 1,   TumVol↓, 2,  
Total Targets: 87

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1)

antiOx↑, 1,  

Drug Metabolism & Resistance(tgid=21)

selectivity↑, 1,  

Functional Outcomes(tgid=23)

toxicity∅, 3,  
Total Targets: 3

Scientific Paper Hit Count for: OS, overall survival
5 Magnetic Fields
4 Magnetic Field Rotating
3 Silver-NanoParticles
3 Radiotherapy/Radiation
2 Phenylbutyrate
1 Hyperthermia
1 chaetocin
1 Choline
1 Coenzyme Q10
1 Electrical Pulses
1 Hydrogen Gas
1 hydroxychloroquine
1 Chemotherapy
1 Juglone
1 mebendazole
1 Noscapine
1 Sulfasalazine
1 Tumor Treating Fields
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:27  Cells:%  prod#:%  Target#:229  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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