VGCC Cancer Research Results

VGCC, Voltage-gated calcium channels: Click to Expand ⟱
Source:
Type: transmembrane proteins
VGCCs play a crucial role in various cellular processes, including cell signaling, proliferation, and differentiation.
VGCCs are transmembrane proteins that regulate the influx of calcium ions into cells. Calcium ions act as a second messenger, triggering various signaling pathways that control cell growth, survival, and migration. In cancer cells, VGCCs can be overexpressed or mutated, leading to aberrant calcium signaling and contributing to tumor growth and metastasis.
Overexpressed in: breast cancer, prostate cancer, colorectal cancer, glioblastoma Associated with: tumor growth, metastasis, and poor prognosis.
GBM, Glioblastoma: Click to Expand ⟱
Glioblastoma is a fast-growing and aggressive brain tumor.
Scientific Papers found: Click to Expand⟱
6809- RF,    Treatment of glioblastoma with tumor-specific amplitude-modulated radiofrequency electromagnetic fields
- in-vitro, GBM, U251
TumCP↓, Dose↝, eff↑, other↝, Dose↝, Dose↝, other↝, VGCC↑, Ca+2↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Transcription & Epigenetics(tgid=7) ⓘ

other↝, 2,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

VGCC↑, 1,  

Migration(tgid=13) ⓘ

Ca+2↑, 1,   TumCP↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 3,   eff↑, 1,  
Total Targets: 6

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: VGCC, Voltage-gated calcium channels
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:27  Cells:%  prod#:%  Target#:758  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

Home Page