TumCD Cancer Research Results

TumCD, Tumor Cell Death: Click to Expand ⟱
Source:
Type:
Tumor Cell Death
GC, Gastric Adenocarcinoma: Click to Expand ⟱
Stomach/Gastric Cancer
Scientific Papers found: Click to Expand⟱
6524- CRV,    d-Carvone inhibits the JAK/STAT3 signaling pathway and induced the apoptotic cell death in the human gastric cancer AGS cells
- in-vitro, GC, AGS
ROS↑, MMP↝, JAK↓, STAT3↓, TumCD↑,
7350- HibSad,    Hibiscus polyphenol-rich extract induces apoptosis in human gastric carcinoma cells via p53 phosphorylation and p38 MAPK/FasL cascade pathway
- in-vitro, GC, AGS
TumCD↑, DNAdam↑, P53↑, Bcl-2↓, Mcl-1↓, Cyt‑c↑, FasL↑, Fas↑, p38↑, BAX↑, Dose↝, TumCCA↑,
2227- SK,    Shikonin induces mitochondria-mediated apoptosis and enhances chemotherapeutic sensitivity of gastric cancer through reactive oxygen species
- in-vitro, GC, BGC-823 - in-vitro, GC, SGC-7901 - in-vitro, Nor, GES-1
selectivity↑, TumCP↓, TumCD↑, ROS↑, MMP↓, Casp↑, Cyt‑c↑, Endon↑, AIF↑, eff↓, ChemoSen↑, TumCCA↑, GSH/GSSG↓, lipid-P↑,

Showing Research Papers: 1 to 3 of 3

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

GSH/GSSG↓, 1,   lipid-P↑, 1,   ROS↑, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 1,   MMP↓, 1,   MMP↝, 1,  

Cell Death(tgid=5) ⓘ

BAX↑, 1,   Bcl-2↓, 1,   Casp↑, 1,   Cyt‑c↑, 2,   Endon↑, 1,   Fas↑, 1,   FasL↑, 1,   Mcl-1↓, 1,   p38↑, 1,   TumCD↑, 3,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 1,   P53↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 2,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

STAT3↓, 1,  

Migration(tgid=13) ⓘ

TumCP↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

JAK↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ChemoSen↑, 1,   Dose↝, 1,   eff↓, 1,   selectivity↑, 1,  
Total Targets: 26

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: TumCD, Tumor Cell Death
1 Carvone
1 Hibiscus sabdariffa
1 Shikonin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:28  Cells:%  prod#:%  Target#:619  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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