MMP-10 Cancer Research Results

MMP-10, Matrix Metalloproteinase-10: Click to Expand ⟱
Source:
Type:
MMP-10, also known as stromelysin-2, is a member of the matrix metalloproteinase family. These enzymes are involved in the degradation and remodeling of the extracellular matrix (ECM), which is critical for normal physiological processes such as wound healing and tissue remodeling.

MMP-10 plays a significant role in cancer progression by promoting ECM degradation and remodeling, which facilitates tumor invasion, metastasis, and overall aggressiveness. Its overexpression in various cancers has been linked to poorer survival outcomes, making it a potential prognostic biomarker.
Cerv, Cervical Cancer: Click to Expand ⟱
Cervical Cancer
Scientific Papers found: Click to Expand⟱
3233- EGCG,    Epigallocatechin gallate inhibits HeLa cells by modulation of epigenetics and signaling pathways
- in-vitro, Cerv, HeLa
DNMTs↓, DNMT1↓, DNMT3A↓, HDAC2↓, HDAC3↓, HDAC4↓, EZH2↓, PI3K↓, Wnt↓, MAPK↓, hTERT/TERT↓, MMP2↓, MMP7↓, IL6↓, MDM2↓, MMP-10↓, TP53↑, PTEN↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

hTERT/TERT↓, 1,   MAPK↓, 1,   MDM2↓, 1,  

Transcription & Epigenetics ⓘ

EZH2↓, 1,  

DNA Damage & Repair ⓘ

DNMT1↓, 1,   DNMT3A↓, 1,   DNMTs↓, 1,   TP53↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

HDAC2↓, 1,   HDAC3↓, 1,   HDAC4↓, 1,   PI3K↓, 1,   PTEN↑, 1,   Wnt↓, 1,  

Migration ⓘ

MMP-10↓, 1,   MMP2↓, 1,   MMP7↓, 1,  

Immune & Inflammatory Signaling ⓘ

IL6↓, 1,  

Clinical Biomarkers ⓘ

EZH2↓, 1,   hTERT/TERT↓, 1,   IL6↓, 1,   TP53↑, 1,  
Total Targets: 22

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: MMP-10, Matrix Metalloproteinase-10
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:29  Cells:%  prod#:%  Target#:1006  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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