Inflam Cancer Research Results

Inflam, inflammation: Click to Expand ⟱
Source:
Type:
Cancer and inflammation are closely linked, with chronic inflammation contributing to the development and progression of cancer. Various inflammatory mediators and cells are involved in this process.


Cerv, Cervical Cancer: Click to Expand ⟱
Cervical Cancer

Scientific Papers found: Click to Expand⟱
5175- Ash,    Withaferin A Induces Proteasome Inhibition, Endoplasmic Reticulum Stress, the Heat Shock Response and Acquisition of Thermotolerance
- in-vitro, Cerv, CCL-102
Inflam↓, AntiTum↑, Proteasome↓, ER Stress↑, HSPs↑, GRP94↑, Akt↑, eff↑, HSP70/HSPA5↑,
5213- PI,    Induction of apoptosis by piperine in human cervical adenocarcinoma via ROS mediated mitochondrial pathway and caspase-3 activation
- in-vitro, Cerv, HeLa
Apoptosis↑, TumCG↓, ROS↑, MMP↓, DNAdam↑, Casp3↑, TumCCA↑, *Inflam↓, *antiOx↓, *hepatoP↑, ChemoSen↑, CSCs↓,
4968- PSO,    Psoralidin: emerging biological activities of therapeutic benefits and its potential utility in cervical cancer
- in-vitro, Cerv, NA
*Inflam↓, *antiOx↑, *neuroP↑, *AntiDiabetic↑, *Bacteria↓, AntiTum↑, CSCs↓, ROS↑, TumAuto↑, Apoptosis↑, ChemoSen↑, RadioS↑, BioAv↓, *cardioP↑, *ROS↓, *LDH↓, TumCP↓, TRAIL⇅, TumCMig↓, EMT↓, NF-kB↓, P53↑, Casp3↑, NOTCH↓, CSCs↓, angioG↓, VEGF↓, Ki-67↓, CD31↓, TRAILR↑, MMP↓, BioAv↓, BioAv↑,

Showing Research Papers: 1 to 3 of 3

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

ROS↑, 2,  

Mitochondria & Bioenergetics

MMP↓, 2,  

Cell Death

Akt↑, 1,   Apoptosis↑, 2,   Casp3↑, 2,   Proteasome↓, 1,   TRAIL⇅, 1,   TRAILR↑, 1,  

Protein Folding & ER Stress

ER Stress↑, 1,   GRP94↑, 1,   HSP70/HSPA5↑, 1,   HSPs↑, 1,  

Autophagy & Lysosomes

TumAuto↑, 1,  

DNA Damage & Repair

DNAdam↑, 1,   P53↑, 1,  

Cell Cycle & Senescence

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State

CSCs↓, 3,   EMT↓, 1,   NOTCH↓, 1,   TumCG↓, 1,  

Migration

CD31↓, 1,   Ki-67↓, 1,   TumCMig↓, 1,   TumCP↓, 1,  

Angiogenesis & Vasculature

angioG↓, 1,   VEGF↓, 1,  

Immune & Inflammatory Signaling

Inflam↓, 1,   NF-kB↓, 1,  

Drug Metabolism & Resistance

BioAv↓, 2,   BioAv↑, 1,   ChemoSen↑, 2,   eff↑, 1,   RadioS↑, 1,  

Clinical Biomarkers

Ki-67↓, 1,  

Functional Outcomes

AntiTum↑, 2,  
Total Targets: 35

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↓, 1,   antiOx↑, 1,   ROS↓, 1,  

Core Metabolism/Glycolysis

LDH↓, 1,  

Immune & Inflammatory Signaling

Inflam↓, 2,  

Clinical Biomarkers

LDH↓, 1,  

Functional Outcomes

AntiDiabetic↑, 1,   cardioP↑, 1,   hepatoP↑, 1,   neuroP↑, 1,  

Infection & Microbiome

Bacteria↓, 1,  
Total Targets: 11

Scientific Paper Hit Count for: Inflam, inflammation
1 Ashwagandha(Withaferin A)
1 Piperine
1 Psoralidin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:29  Cells:%  prod#:%  Target#:953  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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