AntiCan Cancer Research Results

AntiCan, Anticancer Effect: Click to Expand ⟱
Source:
Type: general indicator
Anticancer Effect


Cerv, Cervical Cancer: Click to Expand ⟱
Cervical Cancer
Scientific Papers found: Click to Expand⟱
5472- AF,    Auranofin induces apoptosis and necrosis in HeLa cells via oxidative stress and glutathione depletion
- in-vitro, Cerv, HeLa
TrxR↓, AntiCan↑, TumCG↓, Apoptosis↑, necrosis↑, cl‑PARP↑, MMP↓, ROS↑, GSH↓, eff↓,
4403- AgNPs,    Silver Nanoparticles Decorated UiO-66-NH2 Metal-Organic Framework for Combination Therapy in Cancer Treatment
- in-vitro, GBM, U251 - in-vitro, GBM, U87MG - in-vitro, GBM, GL26 - in-vitro, Cerv, HeLa - in-vitro, CRC, RKO
AntiCan↑, eff↑, EPR↑, selectivity↑, ROS↑, Casp↑, Apoptosis↑, DNAdam↑, tumCV↓, eff↑,
4422- AgNPs,    Bioengineering of Piper longum L. extract mediated silver nanoparticles and their potential biomedical applications
- in-vitro, Cerv, HeLa
AntiCan↑, selectivity↑,
6834- EMD,    Emodin induces apoptosis of human cervical cancer cells through poly(ADP-ribose) polymerase cleavage and activation of caspase-9
- in-vitro, Cerv, HeLa
AntiCan↑, TumCP↓, Apoptosis↑, Casp3↑, Casp9↑, cl‑PARP↑, TumCD↑, DNAdam↑,
7103- GEN,    A Comprehensive Review of Genistein's Effects in Preclinical Models of Cervical Cancer
- Review, Cerv, NA
TumCP↓, Apoptosis↑, RadioS↑, ChemoSen↑, *antiOx↑, *Inflam↓, *Bacteria↓, *AntiViral↑, *AntiDiabetic↑, *neuroP↑, AntiCan↑, TumCG↓, TumCI↓, TumCCA↑, cl‑PARP↑, selectivity↑, CycB/CCNB1↓, CDK1↓, p‑cDC2↓, p‑ERK↓, p‑p38↑, p‑JNK↑, MMP9↓, TIMP1↑, BioAv↓, BioAv↑, Half-Life↑,
4969- PSO,    The Coumarin Psoralidin Enhances Anticancer Effect of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)
- in-vitro, Cerv, HeLa
AntiCan↑, chemoPv↑, TRAIL↑, selectivity↑, toxicity↓, MMP↓, Apoptosis↑,
1984- PTL,    Targeting Thioredoxin Reductase by Parthenolide Contributes to Inducing Apoptosis of HeLa Cells
- in-vitro, Cerv, HeLa
AntiCan↑, TrxR1↓, TrxR2↓, ROS↑, Apoptosis↑, eff↓, eff↑,
5017- UA,    Ursolic acid disturbs ROS homeostasis and regulates survival-associated gene expression to induce apoptosis in intestinal cancer cells
- in-vitro, Cerv, INT-407 - in-vitro, CRC, HCT116
AntiCan↑, TumCG↓, ROS↑, Apoptosis↑, TumCMig↓, CTNNB1↓, Twist↓, Bcl-2↓, survivin↓, NF-kB↓, Sp1/3/4↓, BAX↑, P21↑, P53↑, eff↓, TumCMig↓,

Showing Research Papers: 1 to 8 of 8

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 8

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

GSH↓, 1,   ROS↑, 4,   TrxR↓, 1,   TrxR1↓, 1,   TrxR2↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MMP↓, 2,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 7,   BAX↑, 1,   Bcl-2↓, 1,   Casp↑, 1,   Casp3↑, 1,   Casp9↑, 1,   p‑JNK↑, 1,   necrosis↑, 1,   p‑p38↑, 1,   survivin↓, 1,   TRAIL↑, 1,   TumCD↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Sp1/3/4↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

tumCV↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 2,   P53↑, 1,   cl‑PARP↑, 3,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CycB/CCNB1↓, 1,   P21↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

p‑cDC2↓, 1,   CTNNB1↓, 1,   p‑ERK↓, 1,   TumCG↓, 3,  

Migration(tgid=13) ⓘ

MMP9↓, 1,   TIMP1↑, 1,   TumCI↓, 1,   TumCMig↓, 2,   TumCP↓, 2,   Twist↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

EPR↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

NF-kB↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 1,   ChemoSen↑, 1,   eff↓, 3,   eff↑, 3,   Half-Life↑, 1,   RadioS↑, 1,   selectivity↑, 4,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 8,   chemoPv↑, 1,   toxicity↓, 1,  
Total Targets: 50

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Inflam↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiDiabetic↑, 1,   neuroP↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 1,   Bacteria↓, 1,  
Total Targets: 6

Scientific Paper Hit Count for: AntiCan, Anticancer Effect
2 Silver-NanoParticles
1 Auranofin
1 Emodin
1 Genistein (soy isoflavone)
1 Psoralidin
1 Parthenolide
1 Ursolic acid
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:29  Cells:%  prod#:%  Target#:813  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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