Dose Cancer Research Results
Dose, Dosage: Click to Expand ⟱
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| Type: |
Drug dosage vs efficacy, and actual dosage number of research papers.
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Cerv, Cervical Cancer: Click to Expand ⟱
Scientific Papers found: Click to Expand⟱
ROS↑, lipid-P↑, MMP↓, GSH↓, TumCCA↑, Apoptosis↑, Necroptosis↑, TumCD↑, Dose↝,
TumCD↑, eff↑, TumAuto↑, ER Stress↑, Paraptosis↑, GRP78/BiP↓, Dose↝,
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in-vitro, |
Liver, |
HepG2 |
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in-vitro, |
Cerv, |
HeLa |
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Dose↝, TumCMig↓, Apoptosis↑, necrosis↑, ROS↑, eff↑,
ROS↑, Dose↝, Bcl-2↓, BAX↑, ER Stress↑,
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in-vitro, |
BC, |
MCF7 |
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in-vitro, |
Cerv, |
HeLa |
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in-vitro, |
Lung, |
A549 |
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TrxR↓, Dose↝, eff↑,
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in-vitro, |
Lung, |
H1299 |
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in-vitro, |
BC, |
MCF7 |
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- |
in-vitro, |
Cerv, |
HeLa |
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in-vitro, |
Pca, |
PC3 |
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in-vitro, |
Nor, |
HEK293 |
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Glycolysis↓, GlucoseCon↓, lactateProd↓, PKM2↓, mTOR↓, Hif1a↓, selectivity↑, Dose↝, tumCV↓,
other↝, Glycolysis↓, LDHA↓, Hypoxia↓, Apoptosis↑, lactateProd↓, ATP↓, mt-ROS↑, DNAdam↑, lipid-P↑, AMPK↑, p‑S6K↓, TumCP↓, Dose↝, selectivity↑, i-MDA↑, mtDam↑,
p‑Akt↓, Apoptosis↑, TumCG↓, Dose↝, PI3K↓, eff↑, ATP↓, OCR↓, TumCCA↑, IGF-1↓, angioG↓, TumCI↓,
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in-vitro, |
Ovarian, |
OVCAR-3 |
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in-vitro, |
Cerv, |
HeLa |
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NA, |
NA, |
OV1369 |
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Dose↝, TumCD↑, eff↓, Casp↑, H2O2↑, i-ROS↑,
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in-vitro, |
Cerv, |
HeLa |
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in-vitro, |
sarcoma, |
S180 |
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tumCV↓, ROS↑, *GutMicro↑, BioAv↑, other↝, Dose↝,
Showing Research Papers: 1 to 10 of 10
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 10
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress(tgid=1) ⓘ
GSH↓, 1, H2O2↑, 1, lipid-P↑, 2, i-MDA↑, 1, ROS↑, 4, i-ROS↑, 1, mt-ROS↑, 1, TrxR↓, 1,
Mitochondria & Bioenergetics(tgid=3) ⓘ
ATP↓, 2, MMP↓, 1, mtDam↑, 1, OCR↓, 1,
Core Metabolism/Glycolysis(tgid=4) ⓘ
AMPK↑, 1, GlucoseCon↓, 1, Glycolysis↓, 2, lactateProd↓, 2, LDHA↓, 1, PKM2↓, 1, p‑S6K↓, 1,
Cell Death(tgid=5) ⓘ
p‑Akt↓, 1, Apoptosis↑, 4, BAX↑, 1, Bcl-2↓, 1, Casp↑, 1, Necroptosis↑, 1, necrosis↑, 1, Paraptosis↑, 1, TumCD↑, 3,
Transcription & Epigenetics(tgid=7) ⓘ
other↝, 2, tumCV↓, 2,
Protein Folding & ER Stress(tgid=8) ⓘ
ER Stress↑, 2, GRP78/BiP↓, 1,
Autophagy & Lysosomes(tgid=9) ⓘ
TumAuto↑, 1,
DNA Damage & Repair(tgid=10) ⓘ
DNAdam↑, 1,
Cell Cycle & Senescence(tgid=11) ⓘ
TumCCA↑, 2,
Proliferation, Differentiation & Cell State(tgid=12) ⓘ
IGF-1↓, 1, mTOR↓, 1, PI3K↓, 1, TumCG↓, 1,
Migration(tgid=13) ⓘ
TumCI↓, 1, TumCMig↓, 1, TumCP↓, 1,
Angiogenesis & Vasculature(tgid=14) ⓘ
angioG↓, 1, Hif1a↓, 1, Hypoxia↓, 1,
Drug Metabolism & Resistance(tgid=21) ⓘ
BioAv↑, 1, Dose↝, 10, eff↓, 1, eff↑, 4, selectivity↑, 2,
Total Targets: 50
Pathway results for Effect on Normal Cells:
Clinical Biomarkers(tgid=22) ⓘ
GutMicro↑, 1,
Total Targets: 1
Scientific Paper Hit Count for: Dose, Dosage
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:29 Cells:% prod#:% Target#:1114 State#:% Dir#:4
wNotes=0 sortOrder:rid,rpid
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