PKCδ Cancer Research Results

PKCδ, Protein Kinase C delta: Click to Expand ⟱
Source:
Type:
PKCδ is one of the novel isoforms of the Protein Kinase C (PKC) family, involved in regulating various cellular processes.
It participates in diverse signaling pathways influencing cell proliferation, differentiation, survival, apoptosis, and migration.

In some cancers, PKCδ is upregulated and associated with higher tumor aggressiveness, particularly when it contributes to pathways that promote cell survival and invasion.
Conversely, in other contexts, PKCδ has been reported to act as a tumor suppressor where its activation can promote apoptosis or inhibit cell proliferation.
Colon, Colon Cancer: Click to Expand ⟱
Colon cancer can start anywhere in the colon, (5 feet long) and absorbs water from stool. Rectal cancer starts in the rectum, which is the last 12 centimeters.
Scientific Papers found: Click to Expand⟱
6568- Ger,    Perturbation by geraniol of cell membrane permeability and signal transduction pathways in human colon cancer cells
- in-vitro, Colon, Caco-2
HMG-CoA↓, MMP↓, PKCδ↓, ERK↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Mitochondria & Bioenergetics ⓘ

MMP↓, 1,  

Core Metabolism/Glycolysis ⓘ

HMG-CoA↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

ERK↓, 1,  

Migration ⓘ

PKCδ↓, 1,  
Total Targets: 4

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: PKCδ, Protein Kinase C delta
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:31  Cells:%  prod#:%  Target#:1021  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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