VEGFR1 Cancer Research Results

VEGFR1, vascular endothelial growth factor receptor 1: Click to Expand ⟱

Source:

Type:

VEGFR1 / FLT1 is a VEGF-family receptor involved in angiogenesis, tumor microenvironment signaling, myeloid/macrophage recruitment, tumor-cell migration/survival, metastasis, and pre-metastatic niche formation. In cancer, membrane VEGFR1 activation is generally pro-cancer, while VEGFR1 inhibition is generally anti-angiogenic and anti-metastatic.

Colon, Colon Cancer: Click to Expand ⟱

Colon cancer can start anywhere in the colon, (5 feet long) and absorbs water from stool. Rectal cancer starts in the rectum, which is the last 12 centimeters.

Scientific Papers found: Click to Expand⟱

6271-

DL,

D-limonene rich volatile oil from blood oranges inhibits angiogenesis, metastasis and cell death in human colon cancer cells

in-vitro,

Colon,

SW480

100μg/ml

in-vitro,

Colon,

HT-29

TumCP↓, Apoptosis↑, Bax:Bcl2↑, VEGF↓, angioG↓, TumMeta↓, VEGFR1↓, MMP9↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Cell Death ⓘ

Apoptosis↑, 1, Bax:Bcl2↑, 1,

Migration ⓘ

MMP9↓, 1, TumCP↓, 1, TumMeta↓, 1, VEGFR1↓, 1,

Angiogenesis & Vasculature ⓘ

angioG↓, 1, VEGF↓, 1,
Total Targets: 8

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: VEGFR1, vascular endothelial growth factor receptor 1

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells