antiOx Cancer Research Results

antiOx, anti-oxidant activities: Click to Expand ⟱
Source:
Type:
Various antioxidants such as Nrf2, SODs, catalase, GPxs, PRDXs, and GSTs are altered in different cancers and have been linked to prognosis. Their overexpression can correlate with aggressive tumor behavior and resistance to treatment in many contexts.


Colon, Colon Cancer: Click to Expand ⟱
Colon cancer can start anywhere in the colon, (5 feet long) and absorbs water from stool. Rectal cancer starts in the rectum, which is the last 12 centimeters.


Scientific Papers found: Click to Expand⟱
7414- CS,    Pro-Apoptotic Activity of Artichoke Leaf Extracts in Human HT-29 and RKO Colon Cancer Cells
- in-vitro, Colon, HT29 - in-vitro, CRC, RKO
*antiOx↑, *Inflam↓, tumCV↓, TumCCA↑, Apoptosis↑, eff↑,
6666- DFE,    The impact of date palm fruits and their component polyphenols, on gut microbial ecology, bacterial metabolites and colon cancer cell proliferation
- in-vitro, Colon, Caco-2
*Fibre↑, *Poly↑, *other↝, *QC↑, *Api↑, *Myr↑, *LT↑, TumCP↓, *GutMicro↑, *Inflam↓, *antiOx↑,
6383- Eug,    In Vitro Incorporation of Radioiodinated Eugenol on Adenocarcinoma Cell Lines (Caco2, MCF7, and PC3)
- in-vitro, Colon, Caco-2 - in-vitro, BC, MCF7 - in-vitro, Pca, PC3
antiOx↑, Inflam↓, AntiCan↓, other↝, BioAv↑, other↝,
6341- Eug,    A Metabolomic Investigation of Eugenol on Colorectal Cancer Cell Line HT-29 by Modifying the Expression of APC, p53, and KRAS Genes
- NA, Colon, HT29
*antiOx↑, ROS↑, tumCV↓, P53↑, APC↑, KRAS↓, FAO↓, Glycolysis↓,
6909- FIS,    Modulation of PI3K/ AKT/ mTOR and apoptosis pathway in colon cancer cells by the plant flavonoid fisetin
- in-vitro, Colon, Caco-2
AntiCan↑, tumCV↓, Bcl-2↓, PI3K↓, mTOR↓, NF-kB↓, BAX↑, *AntiDiabetic↑, *AntiCan↑, *Inflam↓, *antiOx↑, *neuroP↑,

Showing Research Papers: 1 to 5 of 5

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1)

antiOx↑, 1,   ROS↑, 1,  

Core Metabolism/Glycolysis(tgid=4)

FAO↓, 1,   Glycolysis↓, 1,  

Cell Death(tgid=5)

Apoptosis↑, 1,   BAX↑, 1,   Bcl-2↓, 1,  

Transcription & Epigenetics(tgid=7)

other↝, 2,   tumCV↓, 3,  

DNA Damage & Repair(tgid=10)

P53↑, 1,  

Cell Cycle & Senescence(tgid=11)

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

mTOR↓, 1,   PI3K↓, 1,  

Migration(tgid=13)

APC↑, 1,   KRAS↓, 1,   TumCP↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

Inflam↓, 1,   NF-kB↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↑, 1,   eff↑, 1,  

Clinical Biomarkers(tgid=22)

KRAS↓, 1,  

Functional Outcomes(tgid=23)

AntiCan↓, 1,   AntiCan↑, 1,  
Total Targets: 23

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1)

antiOx↑, 4,  

Transcription & Epigenetics(tgid=7)

other↝, 1,  

Immune & Inflammatory Signaling(tgid=16)

Inflam↓, 3,  

Clinical Biomarkers(tgid=22)

GutMicro↑, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 1,   AntiDiabetic↑, 1,   neuroP↑, 1,  

Ingredients & Constituents(tgid=25)

Api↑, 1,   Fibre↑, 1,   LT↑, 1,   Myr↑, 1,   Poly↑, 1,   QC↑, 1,  
Total Targets: 13

Scientific Paper Hit Count for: antiOx, anti-oxidant activities
2 Eugenol
1 Cynara scolymus/Globe Artichoke/Artichoke Extract
1 Date Fruit Extract
1 Fisetin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:31  Cells:%  prod#:%  Target#:1103  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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