BioAv Cancer Research Results

BioAv, bioavailability: Click to Expand ⟱
Source:
Type: measurement
Bioavailability (usually in %) absorbed by the body.
Colon, Colon Cancer: Click to Expand ⟱
Colon cancer can start anywhere in the colon, (5 feet long) and absorbs water from stool. Rectal cancer starts in the rectum, which is the last 12 centimeters.
Scientific Papers found: Click to Expand⟱
5439- AG,    Absorption enhancement study of astragaloside IV based on its transport mechanism in Caco-2 cells
- in-vitro, Colon, Caco-2
BioAv↑, BioAv↓,
5753- CA,  QC,  MEL,    Effects of Caffeic Acid and Quercetin on In Vitro Permeability, Metabolism and In Vivo Pharmacokinetics of Melatonin in Rats: Potential for Herb-Drug Interaction
- in-vivo, Colon, Caco-2
BioAv↑, CYP1A1↓,
6083- CHOC,    Preventive Effects of Cocoa and Cocoa Antioxidants in Colon Cancer
- Review, Colon, NA
ROS↓, Inflam↓, TumCP↓, Apoptosis↑, *Dose↝, *BioAv↓, *BioAv↑, GSH↑, GSTs↑, PGE2↓, COX1↑, IL8↓, COX2↓, iNOS↓, NF-kB↓, chemoP↑,
6159- CoQ10,    Increased Bioavailability of Ubiquinol Compared to That of Ubiquinone Is Due to More Efficient Micellarization during Digestion and Greater GSH-Dependent Uptake and Basolateral Secretion by Caco-2 Cells
- in-vitro, Colon, Caco-2
BioAv↑,
6383- Eug,    In Vitro Incorporation of Radioiodinated Eugenol on Adenocarcinoma Cell Lines (Caco2, MCF7, and PC3)
- in-vitro, Colon, Caco-2 - in-vitro, BC, MCF-7 - in-vitro, Pca, PC3
antiOx↑, Inflam↓, AntiCan↓, other↝, BioAv↑, other↝,
6389- Eug,    Molecular Insights into the Management of Eugenol's Anticancer Action Against Colon Cancer: A Detailed Review
- Review, Colon, NA
Apoptosis↓, TumCCA↓, Inflam↓, TumMeta↓, BioAv↑, eff↓, Half-Life↓, *ROS↓, *RNS↓, *SOD↓, *Catalase↑, *GSTs↑, *MAOA↓, *neuroP↑, *DNAdam↓, Apoptosis↑, ROS↑, selectivity↑, MMP↓, Cyt‑c↓, Casp3↑, Casp9↑, TumCD↑, BAX↑, BAD↑, APAF1↑, Bcl-2↓, Bcl-xL↓, P53↑, cl‑PARP↑, TumCCA↑, cycD1/CCND1↓, CycB/CCNB1↓, CDK2↓, CDK4↓, P21↑, p27↑, NF-kB↓, COX2↓, PGE2↓, MAPK↓, PI3K↓, Akt↓, mTOR↓, MMPs↓, EMT↓, Snail↓, Slug↓, Zeb1↓, E-cadherin↑, ChemoSen↑,
4501- SeNPs,    Mechanisms of the Cytotoxic Effect of Selenium Nanoparticles in Different Human Cancer Cell Lines
- in-vitro, GBM, A172 - in-vitro, Colon, Caco-2 - in-vitro, Pca, DU145 - in-vitro, BC, MCF-7 - in-vitro, Nor, L929
*BioAv↑, selectivity↑, AntiCan↑, Apoptosis↑, CHOP↑, GADD34↑, BIM↑, PUMA↑, Ca+2↝,
1507- SFN,    Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects
- in-vivo, Colon, NA - Human, Nor, NA
TumCG↓, HDAC↓, *BioAv↑, Dose∅, Half-Life∅,
6457- TUR,    The Role of Turmerones on Curcumin Transportation and P-Glycoprotein Activities in Intestinal Caco-2 Cells
- in-vitro, Colon, Caco-2
P-gp↑, BioAv↑,
3138- VitC,    The Hypoxia-inducible Factor Renders Cancer Cells More Sensitive to Vitamin C-induced Toxicity
- in-vitro, RCC, RCC4 - in-vitro, CRC, HCT116 - in-vitro, BC, MDA-MB-435 - in-vitro, Ovarian, SKOV3 - in-vitro, Colon, SW48 - in-vitro, GBM, U251
eff↑, Warburg↓, BioAv↑, ROS↑, DNAdam↑, ATP↓, eff↑, necrosis↑, PARP↑,

Showing Research Papers: 1 to 10 of 10

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 10

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,   CYP1A1↓, 1,   GSH↑, 1,   GSTs↑, 1,   ROS↓, 1,   ROS↑, 2,  

Mitochondria & Bioenergetics ⓘ

ATP↓, 1,   MMP↓, 1,  

Core Metabolism/Glycolysis ⓘ

Warburg↓, 1,  

Cell Death ⓘ

Akt↓, 1,   APAF1↑, 1,   Apoptosis↓, 1,   Apoptosis↑, 3,   BAD↑, 1,   BAX↑, 1,   Bcl-2↓, 1,   Bcl-xL↓, 1,   BIM↑, 1,   Casp3↑, 1,   Casp9↑, 1,   Cyt‑c↓, 1,   GADD34↑, 1,   iNOS↓, 1,   MAPK↓, 1,   necrosis↑, 1,   p27↑, 1,   PUMA↑, 1,   TumCD↑, 1,  

Transcription & Epigenetics ⓘ

other↝, 2,  

Protein Folding & ER Stress ⓘ

CHOP↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 1,   P53↑, 1,   PARP↑, 1,   cl‑PARP↑, 1,  

Cell Cycle & Senescence ⓘ

CDK2↓, 1,   CDK4↓, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 1,   P21↑, 1,   TumCCA↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

EMT↓, 1,   HDAC↓, 1,   mTOR↓, 1,   PI3K↓, 1,   TumCG↓, 1,  

Migration ⓘ

Ca+2↝, 1,   E-cadherin↑, 1,   MMPs↓, 1,   Slug↓, 1,   Snail↓, 1,   TumCP↓, 1,   TumMeta↓, 1,   Zeb1↓, 1,  

Barriers & Transport ⓘ

P-gp↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX1↑, 1,   COX2↓, 2,   IL8↓, 1,   Inflam↓, 3,   NF-kB↓, 2,   PGE2↓, 2,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 1,   BioAv↑, 7,   ChemoSen↑, 1,   Dose∅, 1,   eff↓, 1,   eff↑, 2,   Half-Life↓, 1,   Half-Life∅, 1,   selectivity↑, 2,  

Functional Outcomes ⓘ

AntiCan↓, 1,   AntiCan↑, 1,   chemoP↑, 1,  
Total Targets: 73

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

Catalase↑, 1,   GSTs↑, 1,   RNS↓, 1,   ROS↓, 1,   SOD↓, 1,  

DNA Damage & Repair ⓘ

DNAdam↓, 1,  

Synaptic & Neurotransmission ⓘ

MAOA↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 1,   BioAv↑, 3,   Dose↝, 1,  

Functional Outcomes ⓘ

neuroP↑, 1,  
Total Targets: 11

Scientific Paper Hit Count for: BioAv, bioavailability
2 Eugenol
1 Astragalus
1 Caffeic acid
1 Quercetin
1 Melatonin
1 Chocolate
1 Coenzyme Q10
1 Selenium NanoParticles
1 Sulforaphane (mainly Broccoli)
1 Turmerones
1 Vitamin C (Ascorbic Acid)
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:31  Cells:%  prod#:%  Target#:792  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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