TumMeta Cancer Research Results
TumMeta, Cancer Metastasis: Click to Expand ⟱
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Cancer metastasis is the process by which cancer cells spread from the original (primary) tumor to other parts of the body, forming new (secondary) tumors. This occurs when cancer cells invade surrounding tissues, enter the bloodstream or lymphatic system, and travel to distant organs or tissues.
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Bladder, Bladder Cancer: Click to Expand ⟱
Scientific Papers found: Click to Expand⟱
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vitro+vivo, |
Bladder, |
NA |
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tumCV↓, TumCP↓, TumCCA↑, P21↑, p27/CDKN1B↑, cycD1/CCND1↓, cycA1/CCNA1↓, CDK2↓, EMT↓, TumMeta↓, p65↓, p‑p65↓, IKKα↓, NF-kB↑, ROS↑, NRF2↓, HO-1↓, SOD2↓, GPx1↓, Bax:Bcl2↑, TumVol↓,
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in-vitro, |
CRC, |
T24/HTB-9 |
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in-vitro, |
Nor, |
SV-HUC-1 |
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in-vitro, |
Bladder, |
5637 |
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in-vivo, |
NA, |
NA |
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HDAC↓, AntiTum↑, TumCMig↓, AMPK↑, mTOR↑, TumAuto↑, ROS↑, miR-139-5p↑, BMI1↓, TumCI?, E-cadherin↑, N-cadherin↓, Vim↓, Snail↓, cl‑PARP↑, cl‑Casp3↑, BAX↑, Bcl-2↓, Bcl-xL↓, MMP↓, PINK1↑, PARK2↑, TumMeta↓, TumCG↓, LC3II↑, p62↓, eff↓,
Apoptosis↑, TumCG↓, TumCI↓, TumMeta↓, glucoNG↓, ChemoSen↑, TumCCA↑, Casp3↑, Casp7↑, cl‑PARP↑, survivin↓, EGFR↓, HER2/EBBR2↓, ATP↓, Glycolysis↓, mt-OXPHOS↓, AKT1↓, HK2↓, Hif1a↓, ROS↑, NRF2↑, EMT↓, COX2↓, MMP2↓, MMP9↓, Zeb1↓, Snail↓, HDAC↓, HATs↓, MMP↓, Cyt‑c↓, Shh↓, Smo↓, Gli1↓, BioAv↝, BioAv↝, Dose↝,
Showing Research Papers: 1 to 3 of 3
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress(tgid=1) ⓘ
GPx1↓, 1, HO-1↓, 1, NRF2↓, 1, NRF2↑, 1, mt-OXPHOS↓, 1, PARK2↑, 1, ROS↑, 3, SOD2↓, 1,
Mitochondria & Bioenergetics(tgid=3) ⓘ
ATP↓, 1, MMP↓, 2, PINK1↑, 1,
Core Metabolism/Glycolysis(tgid=4) ⓘ
AKT1↓, 1, AMPK↑, 1, glucoNG↓, 1, Glycolysis↓, 1, HK2↓, 1,
Cell Death(tgid=5) ⓘ
Apoptosis↑, 1, BAX↑, 1, Bax:Bcl2↑, 1, Bcl-2↓, 1, Bcl-xL↓, 1, Casp3↑, 1, cl‑Casp3↑, 1, Casp7↑, 1, Cyt‑c↓, 1, p27/CDKN1B↑, 1, survivin↓, 1,
Kinase & Signal Transduction(tgid=6) ⓘ
HER2/EBBR2↓, 1,
Transcription & Epigenetics(tgid=7) ⓘ
HATs↓, 1, tumCV↓, 1,
Autophagy & Lysosomes(tgid=9) ⓘ
LC3II↑, 1, p62↓, 1, TumAuto↑, 1,
DNA Damage & Repair(tgid=10) ⓘ
cl‑PARP↑, 2,
Cell Cycle & Senescence(tgid=11) ⓘ
CDK2↓, 1, cycA1/CCNA1↓, 1, cycD1/CCND1↓, 1, P21↑, 1, TumCCA↑, 2,
Proliferation, Differentiation & Cell State(tgid=12) ⓘ
BMI1↓, 1, EMT↓, 2, Gli1↓, 1, HDAC↓, 2, mTOR↑, 1, Shh↓, 1, Smo↓, 1, TumCG↓, 2,
Migration(tgid=13) ⓘ
E-cadherin↑, 1, miR-139-5p↑, 1, MMP2↓, 1, MMP9↓, 1, N-cadherin↓, 1, Snail↓, 2, TumCI?, 1, TumCI↓, 1, TumCMig↓, 1, TumCP↓, 1, TumMeta↓, 3, Vim↓, 1, Zeb1↓, 1,
Angiogenesis & Vasculature(tgid=14) ⓘ
EGFR↓, 1, Hif1a↓, 1,
Immune & Inflammatory Signaling(tgid=16) ⓘ
COX2↓, 1, IKKα↓, 1, NF-kB↑, 1, p65↓, 1, p‑p65↓, 1,
Drug Metabolism & Resistance(tgid=21) ⓘ
BioAv↝, 2, ChemoSen↑, 1, Dose↝, 1, eff↓, 1,
Clinical Biomarkers(tgid=22) ⓘ
EGFR↓, 1, HER2/EBBR2↓, 1,
Functional Outcomes(tgid=23) ⓘ
AntiTum↑, 1, TumVol↓, 1,
Total Targets: 75
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: TumMeta, Cancer Metastasis
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:32 Cells:% prod#:% Target#:604 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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