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Arthritis, Arthritis: Click to Expand ⟱
Arthritis
Scientific Papers found: Click to Expand⟱
2433- 2DG,    Hexokinase inhibitor 2-deoxyglucose coordinates citrullination of vimentin and apoptosis of fibroblast-like synoviocytes by inhibiting HK2 /mTORC1-induced autophagy
- in-vitro, Arthritis, NA - in-vivo, NA, NA
Vim↓, HK2↓,
3676- Ash,    Effect of Withania somnifera (Ashwagandha) root extract on amelioration of oxidative stress and autoantibodies production in collagen-induced arthritic rats
- in-vivo, Arthritis, NA
*CRP↓, *ROS↓, *lipid-P↓, *GSTs↓, *GSH↑, *antiOx↑, *Inflam↓,
2605- Ba,  BA,    Potential therapeutic effects of baicalin and baicalein
- Review, Var, NA - Review, Stroke, NA - Review, IBD, NA - Review, Arthritis, NA - Review, AD, NA - Review, Park, NA
cardioP↑, Inflam↓, cognitive↑, *hepatoP↑, *ROS?, *SOD↑, *GSH↑, *MMP↑, *GutMicro↑, ChemoSen↑, *TNF-α↓, *IL10↑, *IL6↓, *eff↑, *ROS↓, *COX2↓, *NF-kB↓, *STAT3↓, *PGE2↓, *MPO↓, *IL1β↓, *MMP2↓, *MMP9↓, *β-Amyloid↓, *neuroP↑, *Dose↝, *BioAv↝, *BioAv↝, *BBB↑, *BDNF↑,
1377- BBR,    Berberine inhibits autophagy and promotes apoptosis of fibroblast-like synovial cells from rheumatoid arthritis patients through the ROS/mTOR signaling pathway
- in-vitro, Arthritis, NA
Apoptosis↑, MMP↓, Bax:Bcl2↑, LC3‑Ⅱ/LC3‑Ⅰ↓, p62↑, *ROS↓,
4620- Bor,  BTZ,    Boron Compounds in the Breast Cancer Cells Chemoprevention and Chemotherapy
- Review, Var, NA - Review, Arthritis, NA - Review, Pca, NA
Risk↓, *memory↑, *Dose↑, Risk↓, other↝, *testos↑, other↝, Risk↓, TumCP↓, Apoptosis↑, eff↑,
1417- Bos,    Potential complementary and/or synergistic effects of curcumin and boswellic acids for management of osteoarthritis
- Review, Arthritis, NA
5LO↓, COX2↓, PGE2↓,
1792- CUR,  LEC,    Chondroprotective effect of curcumin and lecithin complex in human chondrocytes stimulated by IL-1β via an anti-inflammatory mechanism
- in-vitro, Arthritis, RAW264.7 - NA, NA, HCC-38
*Inflam↓, *NF-kB↓, *iNOS↓, *COX2↓, *NO↓, *PGE2↓, *MMPs↑, *TIMP1↑, *BioEnh↑,
1418- CUR,    Potential complementary and/or synergistic effects of curcumin and boswellic acids for management of osteoarthritis
- Review, Arthritis, NA
*COX2↓, *Inflam↓, *5LO↓, *NO↓, *NF-kB↓, *TNF-α↓, *IL1↓, *IL2↑, *IL6↓, *IL8↓, *IL12↓, *MCP1↓, *PGE2↓, *MMP2↓, *MMP3↓, *MMP9↓, *NLRP3↓, *ROS↓,
3583- CUR,    Curcumin: an orally bioavailable blocker of TNF and other pro-inflammatory biomarkers
- Review, Arthritis, NA
*TNF-α↓, *IL1β↓, *NF-kB↓, *PGE2↓, *COX2↓, *MMPs↓, *eff↑,
2506- H2,    Molecular hydrogen suppresses activated Wnt/β-catenin signaling
- in-vivo, Arthritis, NA
*Wnt↓, *β-catenin/ZEB1↓, *Dose↝,
2908- LT,    Luteolin attenuates neutrophilic oxidative stress and inflammatory arthritis by inhibiting Raf1 activity
- in-vitro, Arthritis, NA
*ROS↓, *p‑ERK↓, *p‑MEK↓, *Raf↓,
192- MF,    The use of magnetic fields in treatment of patients with rheumatoid arthritis. Review of the literature
- Review, Arthritis, NA
*Dose↝,
4111- MF,    Coupling of pulsed electromagnetic fields (PEMF) therapy to molecular grounds of the cell
- Review, Arthritis, NA
*Inflam↓, *Cartilage↑, *Pain↓, *QoL↑, *Dose↝, *VEGF↑, *NO↑, *TGF-β↑, *MMP9↓, *PGE2↑, *GPx3↑, *SOD2↑, *Catalase↑, *GSR↑, *Ca+2↑,
3566- MF,    Positive and Negative Effects of Administering a Magnetic Field to Patients with Rheumatoid Arthritis (RA)
- Study, Arthritis, NA
*Inflam↓, *QoL↑, *Pain↓, *motorD↑, *toxicity↓, *Cartilage↑, *Inflam↓,
3568- MF,    The Efficacy of Pulsed Electromagnetic Fields on Pain, Stiffness, and Physical Function in Osteoarthritis: A Systematic Review and Meta-Analysis
- Review, Arthritis, NA
*eff↑, *Pain↓, *motorD↑,
3569- MF,    Current Evidence Using Pulsed Electromagnetic Fields in Osteoarthritis: A Systematic Review
- Review, Arthritis, NA
*Pain↓, *QoL↑, *motorD↑,
3536- MF,    Targeting Mesenchymal Stromal Cells/Pericytes (MSCs) With Pulsed Electromagnetic Field (PEMF) Has the Potential to Treat Rheumatoid Arthritis
- Review, Arthritis, NA - Review, Stroke, NA
*Inflam↓, *Diff↑, *toxicity∅, *other↑, *SOX9↑, *COL2A1↑, *NO↓, *PGE2↓, *NF-kB↓, *TNF-α↓, *IL1β↓, *IL6↓, *IL10↑, *angioG↑, *MSCs↑, *VEGF↑, *TGF-β↑, *angioG↝, *VEGF↓, Ca+2↝,
193- MFrot,  MF,    Rotating Magnetic Field Mitigates Ankylosing Spondylitis Targeting Osteocytes and Chondrocytes via Ameliorating Immune Dysfunctions
- in-vivo, Arthritis, NA
BMD↑, Cartilage↑, IL17↓, IL22↓, IL23↓, IL28↓, CD4+↓, CD8+↓, LAMB3↑, COL4↓, THBS2↓, ITGA11↓, PPARγ↑, ACAA1↓, PLIN1↓, FABP4↓, PCK1↓, UCP1↓, TNF-α↓,
3851- MSM,    Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial
- Trial, Arthritis, NA
*Pain↓, *QoL↑,
3847- MSM,    Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement
- Review, Arthritis, NA
*Inflam↓, *Pain↓, *ROS↓, *antiOx↑, *Dose↝, *Half-Life↝, *NF-kB↓, *IL1↓, *IL6↓, *TNF-α↓, *iNOS↓, *COX2↓, *NLRP3↓, *NRF2↑, *STAT↓, *Cartilage↑, *eff↑, *eff↑, *GSH↑, *uricA↓, tumCV↓, TumCCA↑, necrosis↑, Apoptosis↑, VEGF↓, HSP90↓, IGF-1?,
3589- PI,    Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1β-stimulated fibroblast-like synoviocytes and in rat arthritis models
- in-vivo, Arthritis, NA
*IL6↓, *MMP13↓, *PGE2↓, *AP-1↓, *Inflam↓, *5LO↓, *COX1↓, *COX2↓, *ERK↓, *BioEnh↑,
3928- PTS,    The effects of pterostilbene on neutrophil activity in experimental model of arthritis
- in-vivo, Arthritis, NA
*ROS↓, *Neut↓,
3931- PTS,    Pterostilbene Protects against Osteoarthritis through NLRP3 Inflammasome Inactivation and Improves Gut Microbiota as Evidenced by In Vivo and In Vitro Studies
- in-vivo, Arthritis, NA
*Inflam↓, *NLRP3↓, *GutMicro↑, *lipid-P↓, *ROS↓, *Cartilage↑, *IL6↓, *MMP13↓, *Dose↝,
3929- PTS,    New Insights into Dietary Pterostilbene: Sources, Metabolism, and Health Promotion Effects
- Review, Var, NA - Review, Arthritis, NA
*NRF2↑, *BioAv↑, *ROS↓, *Inflam↓, *HO-1↑, *SOD↑, *Catalase↑, *GPx↑, *lipid-P↓, *hepatoP↑, *neuroP↑, *iNOS↓, *COX2↓, TumMeta↓, SOD2↓, ROS↑, TumCI↓, TumCG↓, HDAC1↓, PTEN↑, BP↓, *GutMicro↑,
3926- PTS,    Pterostilbene exert an anti-arthritic effect by attenuating inflammation, oxidative stress, and alteration of gut microbiota
- in-vivo, Arthritis, NA
*Inflam↓, *GutMicro↑, *ROS↓,
3606- QC,    The Effect of Quercetin on Inflammatory Factors and Clinical Symptoms in Women with Rheumatoid Arthritis: A Double-Blind, Randomized Controlled Trial
- Trial, Arthritis, NA
*motorD↑, *Pain↓, *TNF-α↓, *IL8↓, *IL6↓, *IL1β↓, *NF-kB↓, *p38↓,
3343- QC,    Quercetin, a Flavonoid with Great Pharmacological Capacity
- Review, Var, NA - Review, AD, NA - Review, Arthritis, NA
*antiOx↑, *ROS↓, *angioG↓, *Inflam↓, *BioAv↓, *Half-Life↑, *GSH↑, *SOD↑, *Catalase↑, *Nrf1↑, *BP↓, *cardioP↑, *IL10↓, *TNF-α↓, *Aβ↓, *GSK‐3β↓, *tau↓, *neuroP↑, *Pain↓, *COX2↓, *NRF2↑, *HO-1↑, *IL1β↓, *IL17↓, *MCP1↓, PKCδ↓, ERK↓, BAX↓, cMyc↓, KRAS↓, ROS↓, selectivity↑, tumCV↓, Apoptosis↑, TumCCA↑, eff↑, P-gp↓, eff↑, eff↑, eff↑, eff↑, CycB↓, CDK1↓, CDK4↓, CDK2↓, TOP2↓, Cyt‑c↑, cl‑PARP↑, MMP↓, HSP70/HSPA5↓, HSP90↓, MDM2↓, RAS↓, eff↑,
3933- RT,    The Pharmacological Potential of Rutin
- Review, AD, NA - Review, Stroke, NA - Review, Arthritis, NA
*antiOx↑, *neuroP↑, *cardioP↑, *Inflam↓, *TNF-α↓, *IL1β↓, *IL8↓, *COX2↓, *iNOS↓, *NF-kB↓, *cognitive↑, *Cartilage↑, *AntiAg↑, *ROS↓, *lipid-P↓, *hepatoP↑, *ALAT↓, *AST↓, *RenoP↑,
3294- SIL,    Silymarin: a review on paving the way towards promising pharmacological agent
- Review, Nor, NA - Review, Arthritis, NA
*hepatoP↑, *Inflam↓, *chemoP↑, *glucose↓, *antiOx↑, *ROS↓, *ACC↓, *FASN↓, *radioP↑, *NF-kB↓, *TGF-β↓, *AST↓, *α-SMA↝, *eff↑, *neuroP↑, eff↑, ROS↓,
2415- SK,    Shikonin induces programmed death of fibroblast synovial cells in rheumatoid arthritis by inhibiting energy pathways
- in-vivo, Arthritis, NA
Apoptosis?, TumAuto↑, ROS↑, ATP↓, Glycolysis↓, PI3K↓, Akt↓, mTOR↓, *Apoptosis↓, *Inflam↓, *TNF-α↓, *IL6↓, *IL8↓, *IL10↓, *IL17↓, *hepatoP↑, *RenoP↑, PKM2↓, GLUT1↓, HK2↓,
3410- TQ,    Anti-inflammatory effects of thymoquinone and its protective effects against several diseases
- Review, Arthritis, NA
*Inflam↓, *antiOx↑, *COX2↓, *NRF2↑, *HO-1↑, *IL1β↓, *IL6↓, *TNF-α↓, *IFN-γ↓, *PGE2↓, *cardioP↑, *Catalase↑, *SOD↑, *Thiols↑, *neuroP↑, *IL12↓, *MCP1↓, *CXCc↓, *ROS↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 31

Results for Effect on Cancer/Diseased Cells:
5LO↓,1,   ACAA1↓,1,   Akt↓,1,   Apoptosis?,1,   Apoptosis↑,4,   ATP↓,1,   BAX↓,1,   Bax:Bcl2↑,1,   BMD↑,1,   BP↓,1,   Ca+2↝,1,   cardioP↑,1,   Cartilage↑,1,   CD4+↓,1,   CD8+↓,1,   CDK1↓,1,   CDK2↓,1,   CDK4↓,1,   ChemoSen↑,1,   cMyc↓,1,   cognitive↑,1,   COL4↓,1,   COX2↓,1,   CycB↓,1,   Cyt‑c↑,1,   eff↑,8,   ERK↓,1,   FABP4↓,1,   GLUT1↓,1,   Glycolysis↓,1,   HDAC1↓,1,   HK2↓,2,   HSP70/HSPA5↓,1,   HSP90↓,2,   IGF-1?,1,   IL17↓,1,   IL22↓,1,   IL23↓,1,   IL28↓,1,   Inflam↓,1,   ITGA11↓,1,   KRAS↓,1,   LAMB3↑,1,   LC3‑Ⅱ/LC3‑Ⅰ↓,1,   MDM2↓,1,   MMP↓,2,   mTOR↓,1,   necrosis↑,1,   other↝,2,   P-gp↓,1,   p62↑,1,   cl‑PARP↑,1,   PCK1↓,1,   PGE2↓,1,   PI3K↓,1,   PKCδ↓,1,   PKM2↓,1,   PLIN1↓,1,   PPARγ↑,1,   PTEN↑,1,   RAS↓,1,   Risk↓,3,   ROS↓,2,   ROS↑,2,   selectivity↑,1,   SOD2↓,1,   THBS2↓,1,   TNF-α↓,1,   TOP2↓,1,   TumAuto↑,1,   TumCCA↑,2,   TumCG↓,1,   TumCI↓,1,   TumCP↓,1,   tumCV↓,2,   TumMeta↓,1,   UCP1↓,1,   VEGF↓,1,   Vim↓,1,  
Total Targets: 79

Results for Effect on Normal Cells:
5LO↓,2,   ACC↓,1,   ALAT↓,1,   angioG↓,1,   angioG↑,1,   angioG↝,1,   AntiAg↑,1,   antiOx↑,6,   AP-1↓,1,   Apoptosis↓,1,   AST↓,2,   Aβ↓,1,   BBB↑,1,   BDNF↑,1,   BioAv↓,1,   BioAv↑,1,   BioAv↝,2,   BioEnh↑,2,   BP↓,1,   Ca+2↑,1,   cardioP↑,3,   Cartilage↑,5,   Catalase↑,4,   chemoP↑,1,   cognitive↑,1,   COL2A1↑,1,   COX1↓,1,   COX2↓,10,   CRP↓,1,   CXCc↓,1,   Diff↑,1,   Dose↑,1,   Dose↝,6,   eff↑,6,   ERK↓,1,   p‑ERK↓,1,   FASN↓,1,   glucose↓,1,   GPx↑,1,   GPx3↑,1,   GSH↑,4,   GSK‐3β↓,1,   GSR↑,1,   GSTs↓,1,   GutMicro↑,4,   Half-Life↑,1,   Half-Life↝,1,   hepatoP↑,5,   HO-1↑,3,   IFN-γ↓,1,   IL1↓,2,   IL10↓,2,   IL10↑,2,   IL12↓,2,   IL17↓,2,   IL1β↓,7,   IL2↑,1,   IL6↓,9,   IL8↓,4,   Inflam↓,17,   iNOS↓,4,   lipid-P↓,4,   MCP1↓,3,   p‑MEK↓,1,   memory↑,1,   MMP↑,1,   MMP13↓,2,   MMP2↓,2,   MMP3↓,1,   MMP9↓,3,   MMPs↓,1,   MMPs↑,1,   motorD↑,4,   MPO↓,1,   MSCs↑,1,   neuroP↑,6,   Neut↓,1,   NF-kB↓,9,   NLRP3↓,3,   NO↓,3,   NO↑,1,   Nrf1↑,1,   NRF2↑,4,   other↑,1,   p38↓,1,   Pain↓,8,   PGE2↓,7,   PGE2↑,1,   QoL↑,4,   radioP↑,1,   Raf↓,1,   RenoP↑,2,   ROS?,1,   ROS↓,14,   SOD↑,4,   SOD2↑,1,   SOX9↑,1,   STAT↓,1,   STAT3↓,1,   tau↓,1,   testos↑,1,   TGF-β↓,1,   TGF-β↑,2,   Thiols↑,1,   TIMP1↑,1,   TNF-α↓,10,   toxicity↓,1,   toxicity∅,1,   uricA↓,1,   VEGF↓,1,   VEGF↑,2,   Wnt↓,1,   α-SMA↝,1,   β-Amyloid↓,1,   β-catenin/ZEB1↓,1,  
Total Targets: 115

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:35  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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