Apoptosis Cancer Research Results

Apoptosis, Apoptosis: Click to Expand ⟱
Source:
Type: type of cell death
Situation in which a cell actively pursues a course toward death upon receiving certain stimuli.
Cancer is one of the scenarios where too little apoptosis occurs, resulting in malignant cells that will not die.


Arthritis, Arthritis: Click to Expand ⟱
Arthritis


Scientific Papers found: Click to Expand⟱
6300- Cro,    Interaction of saffron and its constituents with Nrf2 signaling pathway: A review
- Review, Nor, NA - Review, Arthritis, NA
*antiOx↑, *Inflam↓, *AntiTum↑, *hepatoP↑, *cardioP↑, *neuroP↑, *NRF2↑, *NF-kB↓, *iNOS↓, *COX2↓, *IL6↓, *IL10↓, *IL1β↓, *TNF-α↓, *HO-1↑, ROS↑, NQO1↑, NRF2↑, HO-1↑, NQO2↑, LDHA↓, ATP↓, *hepatoP↑, *SOD↑, *Catalase↑, *GPx↑, *NRF2↑, *ROS↓, *cardioP↑, *ER Stress↓, *GRP78/BiP↓, *CHOP↓, *Apoptosis↓, *miR-34a↓, *SIRT1↑, chemoP↑,
2415- SK,    Shikonin induces programmed death of fibroblast synovial cells in rheumatoid arthritis by inhibiting energy pathways
- in-vivo, Arthritis, NA
Apoptosis?, TumAuto↑, ROS↑, ATP↓, Glycolysis↓, PI3K↓, Akt↓, mTOR↓, *Apoptosis↓, *Inflam↓, *TNF-α↓, *IL6↓, *IL8↓, *IL10↓, *IL17↓, *hepatoP↑, *RenoP↑, PKM2↓, GLUT1↓, HK2↓,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

HO-1↑, 1,   NQO1↑, 1,   NRF2↑, 1,   ROS↑, 2,  

Mitochondria & Bioenergetics

ATP↓, 2,  

Core Metabolism/Glycolysis

Glycolysis↓, 1,   HK2↓, 1,   LDHA↓, 1,   PKM2↓, 1,  

Cell Death

Akt↓, 1,   Apoptosis?, 1,  

Protein Folding & ER Stress

NQO2↑, 1,  

Autophagy & Lysosomes

TumAuto↑, 1,  

Proliferation, Differentiation & Cell State

mTOR↓, 1,   PI3K↓, 1,  

Barriers & Transport

GLUT1↓, 1,  

Functional Outcomes

chemoP↑, 1,  
Total Targets: 17

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↑, 1,   Catalase↑, 1,   GPx↑, 1,   HO-1↑, 1,   NRF2↑, 2,   ROS↓, 1,   SOD↑, 1,  

Core Metabolism/Glycolysis

SIRT1↑, 1,  

Cell Death

Apoptosis↓, 2,   iNOS↓, 1,  

Protein Folding & ER Stress

CHOP↓, 1,   ER Stress↓, 1,   GRP78/BiP↓, 1,  

Proliferation, Differentiation & Cell State

miR-34a↓, 1,  

Immune & Inflammatory Signaling

COX2↓, 1,   IL10↓, 2,   IL17↓, 1,   IL1β↓, 1,   IL6↓, 2,   IL8↓, 1,   Inflam↓, 2,   NF-kB↓, 1,   TNF-α↓, 2,  

Clinical Biomarkers

IL6↓, 2,  

Functional Outcomes

AntiTum↑, 1,   cardioP↑, 2,   hepatoP↑, 3,   neuroP↑, 1,   RenoP↑, 1,  
Total Targets: 29

Scientific Paper Hit Count for: Apoptosis, Apoptosis
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:35  Cells:%  prod#:%  Target#:14  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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